Ribosome News and Research

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Study Reveals the Surprising Role of Spliceosomes in Introns' Journey

Although you may not appreciate them, or have even heard of them, throughout your body, countless microscopic machines called spliceosomes are hard at work.

13 May 2024

Protein Complex Movement May Regulate Cell Division, Impacting Disease Research

Scientists at Umeå University in Sweden have found that the movement of a unique protein complex known as the Mediator along DNA genes may affect the process of cell division.

6 May 2024

The Assemblage of Nuclear Sub-Structures

Researchers from the lab of Rohit Pappu and associates at the Center for Biomolecular Condensates have figured out how nucleolar sub-structures are assembled, a first for the condensate field.

19 Mar 2024

The Role of RNA Modifications in Stress Granule Dynamics

An intriguing finding regarding how human cells protect themselves under stressful conditions has been revealed in a recent study conducted by an international research team. According to the research, a little genetic alteration known as ac4C serves as an essential defender by assisting cells in producing stress granules, which are units of defense.

28 Feb 2024

Decoding the Secrets of Ribosome Recycling at the Endoplasmic Reticulum

Researchers from Stanford University and LMU have uncovered how cells renew their endoplasmic reticulum’s protein factories.

26 Feb 2024

Retrotransposon-Based PRINT Technique Holds Potential for Precise Gene Insertion

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.

22 Feb 2024

Researchers Redesign the Future of mRNA Therapeutics

Scientists have unearthed that errors in the interpretation of therapeutic mRNA by the cell’s decoding apparatus can incite an inadvertent immune reaction within the body.

7 Dec 2023

Researchers Redesign Future mRNA Therapeutics to Prevent Potentially Harmful Immune Responses

Researchers have discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body.

5 Dec 2023

Ribo-seq Optimization to Gain Insights into Protein Production

Ribosome profiling, a gene sequencing approach, has increased the understanding of the human genome by uncovering previously undiscovered protein-coding regions.

22 Sep 2023

Innovative Method Accelerates Discovery of New Drugs by Harnessing the Power of Ribosomes

A research team led by University of California, Irvine scientists has developed an innovative method for quickly and efficiently creating vast collections of chemical compounds used in drug discovery by harnessing the power of ribosomes, the molecules found in all cells that synthesize proteins and peptides.

24 Aug 2023

Scaffolding Protein Helps in the Creation of Biomolecular Condensate

Biomolecular condensates are loosely organized assemblies that carry out a variety of vital tasks inside all live cells. However, the mechanism by which proteins and other biomolecules combine to create these assemblies within cells is not fully known.

16 Aug 2023

Access of METAPs to Protein Factories is Controlled by NAC

On the basis of genetic blueprints, individual amino acids have been assembled into long amino acid chains, the proteins, in the protein factories of human cells, called the ribosomes.

23 Jun 2023

New Automated Machine Learning Tool to Design and Interpret Biological Sequences

The amount of data generated by scientists today is massive, thanks to the falling costs of sequencing technology and the increasing amount of available computing power.

22 Jun 2023

Reengineering the Cellular Synthetic Machinery to Produce Never-Before-Seen Polymers

Synthetic biologists have become increasingly creative in engineering yeast or bacteria to churn out useful chemicals -; from fuels to fabrics and drugs -; beyond the normal repertoire of microbes.

14 Jun 2023

Natural Peptide From Fruit Flies may Pave Way for New Antibiotics

Scientists at the University of Illinois Chicago have found that a peptide from fruit flies could lead to new antibiotics.

7 Jun 2023

New Delivery Mechanism Brings Messenger RNA to the Point of Need in Neurons

Brain cells manufacture proteins in every corner, including their long branches. Neurons missing this ability cause severe neurological disorders like disability and epilepsy.

5 Jun 2023

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

23 May 2023

Long-Ignored Antibiotic may Provide Much-Needed Protection Against Multi-Drug Resistant Bacteria

An old antibiotic may provide much-needed protection against multi-drug resistant bacterial infections, according to a new study publishing May 16th in the open access journal PLOS Biology by James Kirby of Harvard Medical School, US, and colleagues.

17 May 2023

Revealing an Unanticipated Mechanism for Chaperone-Mediated Ribosome Repair

Researchers have discovered that if oxidative stress destroys protein factories known as ribosomes, repair crews may go in to assist in repairing the damage so that production may restart rapidly.

26 Apr 2023

Two Molecular Mechanisms Combine to Make the Bacterium Extra Resistant

When the intestinal flora is killed by antibiotics, a species of ordinary gut bacteria that humans carry flourishes. Because the bacteria are naturally immune to many drugs, it poses complications, especially in healthcare settings.

18 Apr 2023