Ligand News and Research

RSS

Antibiotics deplete intestinal flora and weaken the immune response

According to a recent study conducted by scientists at Emory University in Atlanta, the administration of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive type of skin cancer, expedited their metastatic bone growth.

12 Sep 2022

Study shows how nanotechnology may help for structural research of RNA molecules

Humans live in a world created and managed by RNA—the genetic molecule DNA’s equally important sibling.

3 May 2022

Researchers develop an antibody as a tool for opening the blood-brain barrier

The brain is composed of billions of neurons-; vulnerable cells that require a protective environment to function properly.

17 Mar 2022

Protein appears key to the function and survival of brain cells most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

2 Mar 2022

New device to assess water quality uses powerful and programmable genetic networks

Northwestern University synthetic biologists have developed a low-cost, easy-to-use, hand-held device that can let users know -; within mere minutes -; if their water is safe to drink.

18 Feb 2022

Study shows how natural products inhibit SARS-CoV-2 main protease Mpro

The fight against the COVID-19 pandemic is a worldwide scientific issue including the development of measures to combat the virus and its harmful effects.

From University of Barcelona 14 Feb 2022

Hemoglobin plays role as a chemosensory signal for mother mice to protect offspring

Biochemists in Japan were surprised to discover that the molecule hemoglobin in the blood works not only as an oxygen carrier, but when the blood is spilled as a result of aggression, accident or predator attack, the molecule also acts as a chemosensory signal -; a chemical stimulus picked up by the senses, namely smell in this case -; for lactating mother mice, prompting digging or rearing behavior in them to check the surrounding environment and keep their offspring safe.

11 Feb 2022

Novel study to identify how immune receptors recognize unique chemical signals on fungal cells

A new study tries to pinpoint the crucial first step in how human immune systems recognize fungal invaders.

From University of Exeter 27 Jan 2022

Treatment with common allergy medication linked to improved immunotherapy response

New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors.

29 Nov 2021

Research could help understand DCIR's role in the pathogenesis of autoimmune diseases

While dendritic cell immunoreceptor (DCIR) is known to mediate inflammation and bone metabolism, ligands that bind DCIR and the mechanisms underlying DCIR activity remain poorly understood.

From Tokyo University of Science 25 Nov 2021

Study identifies new gene that promotes progression to type 1 diabetes

When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.

17 Nov 2021

Gold nanoclusters could be the new weapon in the fight against bacterial antibiotic resistance

Tiny particles of gold could be the new weapon in the fight against bacterial antibiotic resistance, according to research just published.

10 Nov 2021

Researchers predict protein binding based on shape using fastest supercomputer

Proteins attach to one another through a complex mixture of chemical interactions, but what if the process is simpler—like binding due to their shapes?

8 Nov 2021

Study uses artificial evolution to search DNA molecules for light producing deoxyribozymes

Once thought to function primarily as a storage molecule for genetic information, it is now known that DNA can also catalyze chemical reactions. Although such DNA enzymes (deoxyribozymes) have not been identified in nature, they can be isolated in the lab using powerful methods of artificial evolution.

22 Oct 2021

Viral diseases likely to contribute to neurodegeneration, says study

Scientists from DZNE revealed that certain viral diseases can contribute to neurodegeneration.

21 Oct 2021

Structural parameters of phosphatidylglycerol-DNA complex revealed

An interaction of DNA with lipids is of great interest because of their functions. As fatty acids and lipids can specifically bind to nucleic acids forming a code sequence of the genomic DNA, it is important to study the interaction of the oligonucleotide DNA (dA)20-(dT)20 with phosphatidylglycerol by the molecular dynamics method.

24 Sep 2021

Ligand News and Research

Antibiotics deplete intestinal flora and weaken the immune response

Study shows how nanotechnology may help for structural research of RNA molecules

Researchers develop an antibody as a tool for opening the blood-brain barrier

Protein appears key to the function and survival of brain cells most impacted by glaucoma

New device to assess water quality uses powerful and programmable genetic networks

Study shows how natural products inhibit SARS-CoV-2 main protease Mpro

Hemoglobin plays role as a chemosensory signal for mother mice to protect offspring

Novel study to identify how immune receptors recognize unique chemical signals on fungal cells

Treatment with common allergy medication linked to improved immunotherapy response

Research could help understand DCIR's role in the pathogenesis of autoimmune diseases

Study identifies new gene that promotes progression to type 1 diabetes

Gold nanoclusters could be the new weapon in the fight against bacterial antibiotic resistance

Researchers predict protein binding based on shape using fastest supercomputer

Study uses artificial evolution to search DNA molecules for light producing deoxyribozymes

Viral diseases likely to contribute to neurodegeneration, says study

Structural parameters of phosphatidylglycerol-DNA complex revealed

New gene activity sensors, activators could help treat diabetes, cancer, and other disorders

Insect olfaction could be used to help develop drug screening techniques

Natural killer cells target breast cancer using the body’s immune system

NIH grant awarded to model and analyze protein-ligand interactions in cancer research

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics