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Mosquitoes use Salivary Protein to Aid Malaria Parasite Transmission

The study identifies AgApyrase as a key protein in mosquito saliva, enhancing Plasmodium transmission by regulating blood clot breakdown and immune response.

30 Sep 2024

Melbourne Researchers Achieve Breakthrough in Creating Human-Like Blood Stem Cells

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body.

3 Sep 2024

RYBREVANT Receives EC Nod for Advanced Lung Cancer Treatment

Janssen-Cilag International NV, a Johnson & Johnson company, today announced that the European Commission (EC) has approved a Type II extension of indication for RYBREVANT®▼ (amivantamab) in combination with chemotherapy (carboplatin and pemetrexed), for the treatment of adults with advanced non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) Exon 19 deletions (ex19del) or Exon 21 L858R substitution (L858R) mutations, after failure of prior therapy including an EGFR tyrosine kinase inhibitor (TKI).

30 Aug 2024

Study Identifies Three Distinct Subtypes of Clear Cell Renal Cell Carcinoma Using Radiomics and Transcriptomics

Using transcriptomics and radiomics data clustering and its association with molecular characteristics, clinical pathologies, and prognosis to define intrinsic subtypes of ccRCC.

24 Jun 2024

Synthetic Anti-Clotting Agent Derived from Bloodsucking Organisms Saliva

Ticks, mosquitoes, and leeches are endowed by nature with a rapid method of preventing blood clotting while they feed on their host.

14 May 2024

Bacterial "Vampirism" Fuels Deadly Infections

The world's deadliest bacteria actively seek out human blood to feed on, a phenomenon that scientists are referring to as “bacterial vampirism”.

17 Apr 2024

New Research Highlights Gut's Role in Preventing Infections

According to a study published in the journal Nature, gut bacteria and a diet high in the amino acid tryptophan can protect against pathogenic E. coli, which can cause severe upset stomach, cramps, fever, intestinal bleeding, and renal failure.

14 Mar 2024

UMass Amherst Study Shows Promise in Retraining Immune Cells for Targeting Aplastic Anemia

Researchers at the University of Massachusetts Amherst recently released a first-of-its-kind study that focuses on the rare autoimmune disorder aplastic anemia to understand how a subset of cells might be trained to correct the overzealous immune response that can lead to fatal autoimmune disorders.

28 Feb 2024

Understanding How Inherited DNA Variations Influence Blood Cancer Development

Large-scale genetic analysis has helped researchers uncover the interplay between cancer-driving genetic mutations and inherited genetic variants in a rare type of blood cancer.

18 Jan 2024

Novel DNA Tension Probe Technology Offers Precise Measurement of Platelet Function

A novel technique to test platelet function within a person's blood sample is faster, easier and more precise than methods currently in use, an experimental study shows.

12 Dec 2023

Dengue Viruses Subvert Mosquito Biology to Tamp Down Human Immune Responses

The saliva of mosquitoes infected with dengue viruses contains a substance that thwarts the human immune system and makes it easier for people to become infected with these potentially deadly viruses, new research reveals.

5 Apr 2023

Tardigrade proteins for significant advancement in human health

Researchers at the University of Wyoming have made a significant discovery that could one day allow people living in areas without refrigeration to access life-saving treatments.

21 Mar 2023

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

New puzzle challenge taps into the intelligence of Eterna’s users to advance RNA therapeutics

Researchers at UC Santa Cruz working to develop novel RNA-based medicines are teaming up with a new group of collaborators-;players of the online game Eterna.

22 Feb 2023

CHOP scientists build a custom tool that drastically reduces engraftment reporting error rates

Researchers at Children's Hospital of Philadelphiahave developed a custom-built application to automate determination of engraftment, a key outcome after hematopoietic stem cell transplant (HSCT).

31 Jan 2023

Role of VWF in triggering inflammation

The blood clotting protein von Willebrand Factor (VWF) has a new function that has been identified by researchers at RCSI University of Medicine and Health Sciences.

4 Nov 2022

Releasing Wolbachia-infected mosquitoes to protect the global community from dengue

Dengue is the most widespread mosquito-borne disease in the world, and to date, there are no medical treatments for people suffering from this disease.

21 Apr 2022

Researchers identify a set of sporadic genetic mutations behind rare brain malformations

A rare type of brain blood vessel malformation known as a cavernous angioma affects more than one million Americans and carries a lifetime risk of stroke and seizures.

31 Mar 2022

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

A University of South Florida Health (USF Health) preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

1 Feb 2022

Researchers catalog the complete cells that form the blood vessels of the human brain

Researchers at UC San Francisco have cataloged all of the cells that make up the blood vessels in the human brain, as well as their positions and the genes produced.

31 Jan 2022