Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Predicting Disease-Causing Protein Interactions with PIONEER

Predicting Disease-Causing Protein Interactions with PIONEER

Personalized Mini-Brains Provide Insight into Autism Spectrum Disorder

Personalized Mini-Brains Provide Insight into Autism Spectrum Disorder

Melanin May Act as a "Drug Sponge," Influencing Medication Effectiveness

Melanin May Act as a "Drug Sponge," Influencing Medication Effectiveness

Researchers Develop Highly Selective SARS-CoV-2 Mpro Inhibitors

Researchers Develop Highly Selective SARS-CoV-2 Mpro Inhibitors

Fighting Drug-Resistant TB with a Novel Antibiotic

Fighting Drug-Resistant TB with a Novel Antibiotic

Discovering New Drug Targets Through Paralog Hopping

Discovering New Drug Targets Through Paralog Hopping

New AI Model ProteinGenerator Revolutionizes Protein Design with Sequence and Structure Integration

New AI Model ProteinGenerator Revolutionizes Protein Design with Sequence and Structure Integration

One-Third of Antibody Drugs Show Unintended Target Binding

One-Third of Antibody Drugs Show Unintended Target Binding

A Novel Method for Incorporating Non-Canonical Amino Acids into Proteins

A Novel Method for Incorporating Non-Canonical Amino Acids into Proteins

Crystal Structure of i-Motif DNA Opens Doors for Targeted Drug Design

Crystal Structure of i-Motif DNA Opens Doors for Targeted Drug Design

ERS Genomics and Medicines Discovery Catapult Forge CRISPR Licensing Partnership

ERS Genomics and Medicines Discovery Catapult Forge CRISPR Licensing Partnership

New Map Reveals Hidden Interactions Between Receptors and Proteins

New Map Reveals Hidden Interactions Between Receptors and Proteins

RNA Interference Drugs Offer Faster, More Effective Alternative to Traditional Drug Discovery

RNA Interference Drugs Offer Faster, More Effective Alternative to Traditional Drug Discovery

New Human Intestinal Immuno-Organoids Reveal Insights into Immune Cell Dynamics and Cancer Immunotherapy

New Human Intestinal Immuno-Organoids Reveal Insights into Immune Cell Dynamics and Cancer Immunotherapy

Clinical Trials Supported by Genetics Show Higher Success Rates

Clinical Trials Supported by Genetics Show Higher Success Rates

Enhanced Drug Discovery with Novel Sulfur Fluoride Exchange Reagent

Enhanced Drug Discovery with Novel Sulfur Fluoride Exchange Reagent

Advancing Cardiovascular Drug Discovery: Translational Framework Leverages Genetic and Proteomic Insights

Advancing Cardiovascular Drug Discovery: Translational Framework Leverages Genetic and Proteomic Insights

Emerging Treatments and Drug Repositioning for NAFLD and NASH

Emerging Treatments and Drug Repositioning for NAFLD and NASH

Breakthrough Compound ZTA-261 Shows Promise for Safer Lipid Disorder Treatment

Breakthrough Compound ZTA-261 Shows Promise for Safer Lipid Disorder Treatment

Exploring Drug Repurposing For Arboviral Infections Through Cavitomix

Exploring Drug Repurposing For Arboviral Infections Through Cavitomix

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