Organelle News and Research

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Innovative Approach Supercharges T Cells by Transferring Healthy Mitochondria

Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell exhaustion.

16 Sep 2024

Mitochondrial DNA 'Jumps' to Chromosomes, Potentially Impacting Lifespan

As direct descendants of ancient bacteria, mitochondria have always been a little alien.

23 Aug 2024

New Insights into How Cell Nuclei Shape Tissue Architecture During Development

In work conducted both at UC Santa Barbara and the Physics of Life Excellence Cluster of TU Dresden, biophysicist Otger Campàs and his research group have found that cell nuclei control the architecture and mechanics of eye and brain tissues during embryonic development.

13 Aug 2024

Unraveling the Rhizobia-Diatom Relationship in the Ocean

Nitrogen is an essential component of all living organisms. It is also the key element controlling the growth of crops on land, as well as the microscopic oceanic plants that produce half the oxygen on our planet.

10 May 2024

Study Reveals How Cells Recycle Proteins in Response to Nutrient Starvation

A new study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions.

15 Apr 2024

OrthoID Method Revolutionizes Protein Identification in Organelle Communication

A collaboration between POSTECH, Daegu Catholic University School of Medicine, and Seoul National University unveils a novel strategy for identifying key proteins in organelle communication.

15 Apr 2024

New Solvatochromic Dye Could Revolutionize Real-Time Lipid Order Imaging

A new solvatochromic probe could help shed light on the relationship between lipid membrane fluidity and various cellular functions, report scientists at Tokyo Institute of Technology and Kyushu University.

14 Mar 2024

Constructing a Structured Illumination Microscopy Add-On

EPFL scientists have recently released a comprehensive manual detailing the construction of an add-on that can transform a regular optical microscope into a cutting-edge tool capable of generating high-resolution, three-dimensional images of cells, organoids, and embryos.

5 Mar 2024

Scientists Unleash the Power of Calcium to Target and Destroy Tumor Cells

Calcium ions are essential for cells, but can be toxic in higher concentrations. A team of researchers has now designed and prepared a combination drug that kills tumor cells by modulating the calcium influx into the cell.

30 Jan 2024

Golgi Organelle's Crucial Role in Stress Responses

For more than a century, scientists have been aware of a certain organelle found in plant cells. That organelle's crucial function in aging, however, has only recently been uncovered by UC Riverside scientists.

18 Jan 2024

Cracking the Code of the Cytoplasm: How Cells Organize Protein Production

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

22 Dec 2023

Zika's Enzyme Cascade Holds the Key to Viral Replication

Viruses operate with limited genetic material and a sparse protein repertoire, requiring efficient utilization of their components. The Zika virus serves as an illustrative case, producing only 10 proteins.

11 Dec 2023

Plants Exploit Randomness to Avoid Mitochondrial Damage

Humans wouldn't last long without plant mitochondria and chloroplasts. These essential compartments of plant cells famously capture sunlight and power plant life – and so, ultimately, provide all the food we eat.

7 Nov 2023

Rab32 and Rab38 Crucial for Bone Resorption and Pigmentation of Skin, Hair

Bone is maintained via delicate balance between formation and resorption, and its imbalance leads to bone related diseases like osteoporosis rheumatism and periodontitis.

26 Oct 2023

The Exclusome, A New Mammalian "Container"

We speak to Dr. Ruth Kroschewski about new research that details the existence of an 'exclusome', a cytoplasmic container that appears to explain where extra-chromosomal DNA goes once it is in a cell.

24 Oct 2023

MIT Chemists Discover Structure of SARS-CoV-2 Ion Channel in Open State

The genome of the SARS-CoV-2 virus encodes 29 proteins, one of which is an ion channel called E. This channel, which transports protons and calcium ions, induces infected cells to launch an inflammatory response that damages tissues and contributes to the symptoms of Covid-19.

16 Oct 2023

New Synthetic Biology Approach Offers Promise for Treating Neurodegenerative Diseases

Researchers at the University of Cologne's CECAD Cluster of Excellence for Aging Research and the CEPLAS Cluster of Excellence for Plant Sciences have found a promising synthetic plant biology approach for the development of a therapy to treat human neurodegenerative diseases, especially Huntington's disease.

3 Oct 2023

Kanazawa University Research: Researchers Define a Protocol for Narrow Cantilever Fabrication and High-Resolution Imaging of Living Cells Using AFM

Researchers at Kanazawa University report in STAR Protocols procedural details and tips for nanoendoscopy-AFM, for capturing images of nanoscale structures inside living cells.

12 Sep 2023

NSL Complex Regulates Intraciliary Transport Genes in Multiple Cell Types

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown in both fruit flies and mammals to regulate the expression of thousands of genes. Abrogation of the NSL genes causes the organism to die, which gives rise to the complex’s unusual name.

28 Aug 2023

Gene Therapy Shows Promise for Muscular Dystrophy Patients

Researchers at Cincinnati Children’s Hospital reveal how damage to the cell’s energy factory causes muscle wasting. Closing a pore in the mitochondrial membrane in gene-edited mice prevents disease progression.

28 Aug 2023