Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

New Insights Into the Role of p53 in Intestinal Inflammation

A group of scientists from Charité – Universitätsmedizin and the Berlin Institute for Medical Systems Biology of the Max Delbrück Center have provided fresh insight into the pathophysiology of ulcerative colitis an inflammatory bowel disease that affects an estimated five million people globally and is associated with a higher risk of colon cancer.

28 Oct 2024

Personalized Mini-Brains Provide Insight into Autism Spectrum Disorder

Using stem cells generated from patients with a rare and severe form of autism spectrum disorder and intellectual disability, Scripps Research scientists have grown personalized "mini-brains" (or organoids) to study the disorder in new detail.

24 Oct 2024

Research Advances Understanding of Gene Expression Mechanisms

During embryonic development, cells start out as pluripotent, or have the potential to become many different cell types through differentiation.

17 Oct 2024

Transposable Elements Drive a Critical Transition in Early Embryogenesis

Researchers at Sinai Health have discovered that DNA elements known as transposons, which may travel throughout the genome, control a crucial stage in early human development instead of human genes.

16 Oct 2024

Transposable Elements Are Key to Normal Progression of Embryonic Cells

A critical transition in early human development is regulated not by our own genes, but by DNA elements called transposons that can move around the genome, Sinai Health researchers have found.

16 Oct 2024

Researchers Develop Innovative Human Macrophage Model for Disease Study

A human cell culture model of the lung's most important immune cells, alveolar macrophages, helped make a key finding that is prompting researchers to rethink the role of another immune protein in infectious disease.

15 Oct 2024

New Insights into How Plants Regulate Growth and Development

Plants form new leaves, flowers and roots at the tips of shoots and roots, in specific growth regions known as meristems. These meristems contain stem cells that divide as needed and form new cells that develop into specialized tissue.

15 Oct 2024

Human Skin Map Gives ‘Recipe’ to Build Skin and Could Help Prevent Scarring

For the first time, researchers have created a single cell atlas of prenatal human skin to understand how skin forms, and what goes wrong in disease.

From Wellcome Sanger Institute 14 Oct 2024

New Research Examines the Role of Skeletal Stem Cells in Bone Growth and Regeneration

Researchers at UTHealth Houston have been awarded an $8.1 million grant by the National Institutes of Health (NIH) to examine skeletal stem cells as potential drivers of craniofacial bone diseases and deformities. The study is led by Noriaki Ono, DDS, PhD, associate professor of orthodontics, and diagnostic and biomedical sciences at UTHealth Houston School of Dentistry.

14 Oct 2024

New Insights Into Early Brain Development and Mental Health

An unparalleled glimpse at how gene regulation changes during human brain development has been provided by a study led by UCLA, which demonstrates the crucial role played by the 3D structure of chromatin, which is made up of proteins and DNA.

10 Oct 2024

New Approach Aims to Enhance CRISPR Safety and Precision

CRISPR is a revolutionary tool that allows scientists to precisely modify the genome and gene expression of cells in any organism.

8 Oct 2024

Human Stem Cell-Derived Retinal Organoid Sheets Close Macular Holes

Researchers reported in the journal Stem Cell Reports that retinal holes in a monkey model were successfully healed by transplanting human stem cells. Following transplantation, retinal tissue was continuously added to the macular holes to seal them.

4 Oct 2024

A New Understanding of Chromatin Regulation and its Implications

Human survival is dependent upon an extraordinarily intricate dance that takes place inside every cell and every nucleus. DNA is continually being wrapped and unwrapped by proteins, and even small mistakes might result in cancer.

3 Oct 2024

Tuft Cells: A New Hope for Gut Healing

Immunological cues cause intestinal tuft cells to proliferate and create new cells. Furthermore, tuft cells can withstand severe damage, such as radiation damage, and aid in the regeneration of the epithelium, in contrast to progenitor- and stem cells.

3 Oct 2024

Human Cells Exhibit Dormant State Similar to Embryonic Diapause

In some mammals, the timing of the normally continuous embryonic development can be altered to improve the chances of survival for both the embryo and the mother.

27 Sep 2024

Stem Cell Study Reveals Developmental Dance Behind Individual Variation

Researchers at the Johns Hopkins University School of Medicine have conducted a comprehensive analysis of the variations present in human stem cells. This study sheds light on how the unique “developmental dance” at the molecular level within an individual's cells can shape the formation of the brain and the body.

26 Sep 2024