Drug Discovery and Manufacturing News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Further Reading

Non-steroidal anti-inflammatory drugs reduce antibody and inflammatory responses to COVID-19

Non-steroidal anti-inflammatory drugs reduce antibody and inflammatory responses to COVID-19

Novel compounds may lead to potential treatment for rare terminal childhood illness

Novel compounds may lead to potential treatment for rare terminal childhood illness

Study demonstrates drug repurposing can be used to treat genetic diseases

Study demonstrates drug repurposing can be used to treat genetic diseases

Scientists identify new target to deliver anti-cancer drugs to tumor cells

Scientists identify new target to deliver anti-cancer drugs to tumor cells

Study shows metabolic state of disease-causing parasite influences its resistance to drugs

Study shows metabolic state of disease-causing parasite influences its resistance to drugs

Researchers identify potential new treatments for blindness

Researchers identify potential new treatments for blindness

Study shows how drug-like small molecules regulate the activity of ion channels

Study shows how drug-like small molecules regulate the activity of ion channels

Interpretable machine learning models create new options for drug discovery

Interpretable machine learning models create new options for drug discovery

New protein imaging technique may lead to advanced tissue analysis

New protein imaging technique may lead to advanced tissue analysis

Several hepatitis C drugs can inhibit the SARS-CoV-2 main protease

Several hepatitis C drugs can inhibit the SARS-CoV-2 main protease

New way to predict who will respond to cancer therapies that block Wnt production

New way to predict who will respond to cancer therapies that block Wnt production

Study suggests that melatonin may be a viable treatment option for COVID-19

Study suggests that melatonin may be a viable treatment option for COVID-19

Study may help develop new antiviral drugs against COVID-19

Study may help develop new antiviral drugs against COVID-19

Genetic predispositions affect the efficacy of COVID-19 drugs

Genetic predispositions affect the efficacy of COVID-19 drugs

Study sheds new light on penicillin allergy

Study sheds new light on penicillin allergy

Experimental AI platform predicts best approach to cancer treatment

Experimental AI platform predicts best approach to cancer treatment

Statins can reduce risk of heart attacks and other cardiovascular diseases

Statins can reduce risk of heart attacks and other cardiovascular diseases

Researchers identify specific neurons that may contribute to epileptic seizures

Researchers identify specific neurons that may contribute to epileptic seizures

Researchers demonstrate mysterious molecular concept for targeted drug delivery

Researchers demonstrate mysterious molecular concept for targeted drug delivery

Study offers new treatment strategies for HIV

Study offers new treatment strategies for HIV

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