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Understanding Lactate's Role in Energy Metabolism

As a student competing in track and field at his Parlier high school, Robert Leija was obsessed with how to improve his performance and, in particular, prevent the buildup of lactic acid in his muscles during training.

16 May 2024

Glycosylation and its Role in Human Health and Disease

The current understanding of glycosylation genetics in mammals and the consequences of mutations that impact glycosylation.

16 May 2024

Unlocking the Genetics of Coral-Destroying Crown-of-Thorns Starfish

Scientists are one step closer to combatting coral-destroying crown-of-thorns starfish, following a University of Queensland study into the pest's genetics.

15 May 2024

Researchers Uncover More Genes Linked to Clonal Hematopoiesis

Researchers have identified 17 more genes that cause the aberrant proliferation of blood cells with mutations as humans age. The results were published in the journal Nature Genetics.

15 May 2024

New Technique Reveals Microscopic Heart Vessels with Unprecedented Clarity

A new imaging technique tested in patients could improve the evaluation of cardiac conditions and undiagnosed chest pain.

7 May 2024

New Study Sheds Light on Genetic Adaptations of Papua New Guinean Populations

Papua New Guinea (PNG) has a wide range of environments, each presenting unique challenges to human survival. Highlanders and lowlanders of PNG are striking examples of populations facing distinct environmental stress.

2 May 2024

New Organoid Model Offers Opportunities to Study Thymus Function

Researchers from the Organoid group have developed a new organoid model that can be used to study the thymus.

30 Apr 2024

Sphingolipid Mystery Solved: S1P May Protect Against Coronary Artery Disease

Weill Cornell Medicine investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related molecule known as a sphingolipid, suggesting a promising new strategy for the treatment of coronary artery disease.

25 Apr 2024

KIT Researchers Uncover New Cell Type Responsible for Vascular Growth

Cardiovascular diseases, including stroke and myocardial infarction, are the world's leading causes of mortality, accounting for over 18 million deaths a year.

18 Apr 2024

Exercise Intervention Reduces Fat Accumulation Associated with Aging

Scientists have discovered that a type of fat accumulates as tissue ages and that this accumulation can be reversed through exercise.

16 Apr 2024

How Glucocorticoids Quell Inflammation

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions.

13 Apr 2024

New Virus Offers Hope for Amphibians Ravaged by Fungus

A fungus devastating frogs and toads on nearly every continent may have an Achilles heel. Scientists have discovered a virus that infects the fungus, and that could be engineered to save the amphibians.

4 Apr 2024

New Model Captures Multiple Factors Driving Alpha-Synuclein Aggregation

Using computational models, researchers have delved into the factors behind the buildup of alpha-synuclein protein, a significant player in the progression of Parkinson’s disease.

3 Apr 2024

Rare YKT6 Gene Variants Linked to New Neurological Disorder

A recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characterized by developmental delays along with severe progressive liver disease and a potential risk for liver cancer.

2 Apr 2024

Cells Harvested From Urine May Have Diagnostic Potential for Kidney Disease

Genes expressed in human cells harvested from urine are remarkably similar to those of the kidney itself, suggesting they could be an important non-invasive source of information on the kidney.

20 Mar 2024

Adhesion GPCR Mayo Plays Key Role in Midgut Development of Fruit Flies

Adhesion GPCRs belong to the large family of G protein-coupled receptors (GPCRs). There are about 700 variants in humans, which are responsible for sensory impressions, hormonal cycles, controlling the cardiovascular system and more.

18 Mar 2024

Biological Glue Provides Clues About Cardiovascular Diseases

University of Virginia School of Medicine scientists have found important answers about strokes, heart attacks and cardiovascular diseases by probing the biological glue our bodies create to protect us from those deadly dangers.

12 Mar 2024

AI Research Gives Unprecedented Insight Into Heart Genetics and Structure

A ground-breaking research study has used AI to understand the genetic underpinning of the heart’s left ventricle, using three-dimensional images of the organ.

12 Mar 2024

New Therapeutic Devices for Diseases with ‘Internet of Life’

Although an electronic gadget and E. coli bacteria might not seem to have much in common, University of Maryland researchers recently connected them to create the first closed-loop system capable of communication across the technological and biological divide.

6 Mar 2024