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Study Demonstrates How the Warburg Effect is Crucially Linked to Cancer Progression

Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming.

3 May 2024

Circadian Coordination: Key to Tissue Function and Aging Prevention

Discovered in the 1970s, circadian clocks are essential for the regulation of biological time in most cells in the human body.

3 May 2024

St. Jude Scientists Reveal Role of Non-Coding DNA Variants in Childhood Leukemia

St. Jude Children's Research Hospital scientists have identified specific DNA variants in the non-coding regions of the genome contributing to chemotherapy resistance in acute lymphoblastic leukemia (ALL).

2 May 2024

Novel Lantibiotic Unveiled Against Skin Microbiome Rivals

Many bacteria produce substances to gain an advantage over competitors in their highly competitive natural environment.

30 Apr 2024

Unlocking Brown Fat's Potential: Study Reveals Key Protein in Obesity Regulation

Brown fat, also known as brown adipose tissue (BAT), is a type of fat in our bodies that's different from the white fat around our belly and thighs that we are more familiar with.

30 Apr 2024

Mapping Small Molecule-Protein Interactions for Drug Development

For most human proteins, there are no small molecules known to bind them chemically (so called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel medicines.

30 Apr 2024

Harmless Particles Enhance Immune Response, Study Finds

Our lungs are bombarded by all manner of different particles every single day. Whilst some are perfectly safe for us, others-;known as pathogens-;have the potential to make us ill.

29 Apr 2024

The Evolution of CRISPR Technology in Combatting Antimicrobial Resistance

Assistant Professor Ibrahim Bitar of the Department of Microbiology, Faculty of Medicine, University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic, will provide an overview of the molecular biology of CRISPR technology and highlight its potential applications in combating antimicrobial resistance in the second new research review.

29 Apr 2024

Study Unravels How Tumors Evade Immune Response by Targeting T Cells

Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer.

25 Apr 2024

Immune System's Standby Mode: Healthy Tissue Keeps Defenses Ready

When pathogens invade the body, the immune system must react immediately to prevent or contain an infection.

25 Apr 2024

Small RNA-Binding Protein Promotes Prime Editing Efficiency

Through years of engineering gene-editing systems, researchers have developed a suite of tools that enable the modification of genomes in living cells, akin to 'genome surgery'.

23 Apr 2024

Unveiling Cannabinoid’s Potential for Treating Age-Related Brain Degeneration

Scientists at the Salk Institute observed the neuroprotective effects of cannabinol in fruit flies and discovered cannabinoid analogs that may prove to be promising future treatments for Parkinson's, Alzheimer's, and traumatic brain injury.

18 Apr 2024

U of T Scientists Make Breakthrough Discovery in DNA Repair Mechanism

Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.

18 Apr 2024

Mysterious Plasmid in Human Gut Holds Potential for Health Hazard Detection

A component of the human intestinal flora that has been little studied to date is the focus of a new study.

17 Apr 2024

Nasal Cells in Children Shield Against Severe COVID-19

Children usually have milder COVID-19 symptoms; this could be due to differences in how elderly and young people's nasal cells react to the SARS-CoV-2 virus.

16 Apr 2024

Genetic Link to Persistent HPV Infections Identified

Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide.

15 Apr 2024

Genomic Deletions Drive Development of Melanoma Drug Resistance

Melanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to alleviate the health burden of the disease. Important advances in recent years include doctors using genetic tests to look for specific mutations they can target for more personalised, effective treatment.

15 Apr 2024