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Epigenomic Analysis Reveals Potential Treatment Avenues for ALS

For most patients, it's unknown exactly what causes amyotrophic lateral sclerosis (ALS), a disease characterized by degeneration of motor neurons that impairs muscle control and eventually leads to death.

3 May 2024

Researchers Make Fundamental Discovery to Combat Fusarium Head Blight in Wheat

Fungal disease Fusarium head blight (FHB) is on the rise due to increasingly humid conditions induced by climate change during the wheat growing season, but a fundamental discovery by University of Adelaide researchers could help reduce its economic harm.

26 Apr 2024

Genomic Research Unravels Arabica Coffee's Ancient Origins

The key to growing coffee plants that can better resist climate change in the decades to come may lie in the ancient past.

16 Apr 2024

Understanding Prostate Cancer Disparities Through Proteogenomics

Certain proteogenomic signatures in the prostate cancers of men of African and European ancestries were associated with higher risk of metastasis and/or recurrence of the disease, according to a study presented at the American Association for Cancer Research (AACR) Annual Meeting 2024, held April 5-10.

10 Apr 2024

Microsatellites' Stability Through Deep Time: Insights from Adélie Penguin Genomes

Microsatellites are valuable tools for studying inheritance, genetic diversity, and population dynamics across a wide range of organisms including bacteria, plants, animals, and fungi. These

2 Apr 2024

Study Reveals Crucial Protein’s Role in Brain Cell Development

Scientists from the University of Wisconsin–Madison have pinpointed a crucial protein associated with the formation of a specific type of brain cell implicated in conditions such as Alzheimer’s and Parkinson’s diseases.

20 Nov 2023

Study Identifies Risk Genes and Regulatory Variants for Colorectal Cancer by Integrating Multi-Omics Data

This study was led by Prof. Xiao-Ping Miao' team from the School of Public Health, Wuhan University, in collaboration with Prof. Shaokai Zhang from the Henan Cancer Hospital.

2 Nov 2023

Genetically Modified iPS Cell Applications for Fabry Disease

iPS cells have had a significant impact on biology and medicine, and they are expected to increase regenerative medicine. Clinical trials with various cell types derived from iPS cells have been performed since 2014 when a sheet of retinal pigment epithelial cells obtained from iPS cells was transplanted into patients with age-related macular degeneration.

4 Jul 2023

New Breakthrough of Genetic Marker Improves Treatment for Multiple Sclerosis

A study of more than 22,000 people with multiple sclerosis has discovered the first genetic variant associated with faster disease progression, which can rob patients of their mobility and independence over time.

29 Jun 2023

How Do Humans Maintain a Healthy Blood Sugar Level After Meals?

A study of more than 55,000 people’s DNA from around the world has given insight into how humans maintain appropriate blood sugar levels after eating, with implications for the current understanding of how the process goes awry in type 2 diabetes.

9 Jun 2023

Strawberry Inflorescence Research Provides Tools for Genomics-Based Plant Breeding

Researchers from the University of Helsinki, in collaboration with their Canadian colleagues, have demonstrated how strawberry inflorescence development is dictated by the small growing points, called meristems.

7 Apr 2023

SoyOmics: An Innovative Framework of Multi-omics Database for Soybean

A major source of plant oil and protein for humans is the soybean (Glycine max (L.) Merr.), a crop cultivated all over the globe. The main objective for geneticists and breeders is to increase soybean production and quality.

5 Apr 2023

Key gene involved in crop alkaline tolerance discovered

Chinese scientists have identified a key gene involved in crop alkaline tolerance that may greatly improve crop yield in sodic environments through the use of genetic engineering.

24 Mar 2023

Immunity adaptation found in genomes of Stone Age farmers

New research suggests that diversity in genes implicated in immunity might have facilitated the shift from hunter-gatherer lifestyles to agriculture that occurred in prehistoric Europe over the course of around 1,500 years.

23 Mar 2023

Study reveals the cellular composition and circuit organization of the locus coeruleus

A small nucleus in the brainstem called locus coeruleus (literally the "blue spot,") is the primary source of a major neuromodulator, norepinephrine (NE), an important mediator of the 'fight or flight' response in animals. However, very little is known about the local connections of this small albeit critically important group of neurons.

16 Mar 2023

Unique genes create new species of monkeyflower

Monkeyflowers glow in a rich assortment of colors, from yellow to pink to deep red-orange. But about 5 million years ago, some of them lost their yellow.

10 Feb 2023

New database of genotype-phenotype associations for monogenic cardiovascular diseases

Monogenic cardiovascular disease is a genetic disease in which cardiovascular damage is the only or main phenotype. The total current number of patients worldwide exceeds 10 million.

9 Feb 2023

Novel insight into how stress changes in dynamic social systems

Stress is ubiquitous in today's world and affects people's lives significantly. Past research has focused on how stress is transmitted between pairs of individuals and in small groups. In a new longitudinal study, researchers adopted a network perspective to examine how the distribution of stress in an individuals' social environment influences their appraisal of stress.

8 Feb 2023

Breeding experiment to uncover genes that encourage plants to cooperate

According to a recent study published in PLOS Biology on November 29th, 2022 by Samuel Wuest of the University of Zurich and Agroscope, Switzerland, and colleagues, a clear and simple breeding experiment combined with genetic analysis can quickly uncover genes that promote cooperation and higher yields of plant populations.

1 Dec 2022

The genetic mechanisms that induce protein decline in modern maize

The wild ancestor of maize, teosinte, contains three times as much seed protein as the majority of cultivars of maize today. The mechanisms causing the declining seed protein content in maize hybrids and inbred lines were identified by researchers at the Chinese Academy of Sciences Headquarters.

17 Nov 2022