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Runt Transcription Factor Links Regeneration and Photosynthesis in Marine Worm-Algae Symbiosis

Many organisms are far more complex than just a single species. Humans, for example, are full of a variety of microbes.

16 May 2024

Machine Learning Program Offers Insights Into Promoter Sequences and Transcription

A team led by researchers at UT Southwestern Medical Center developed deep learning models to identify a simple set of rules that govern the activity of promoters – regions of DNA that initiate the process by which genes produce proteins.

15 May 2024

Transcriptomic Analysis Reveals Age-Dependent Gene Expression Patterns in Mouse Sweat Glands

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "Characterization of age-associated gene expression changes in mouse sweat glands."

15 May 2024

Single-Molecule Study Reveals Unexpected Role of Protein Stiffness in Nuclear Transport

The degree of softness or rigidity in specific regions of proteins can affect how quickly or slowly those proteins enter the nucleus, according to research from the Francis Crick Institute and King's College London.

14 May 2024

Decoding Chromatin Modifications: A Breakthrough in Epigenome Editing

An epigenome editing platform and a method to program nine major chromatin modifications.

14 May 2024

Study Reveals the Surprising Role of Spliceosomes in Introns' Journey

Although you may not appreciate them, or have even heard of them, throughout your body, countless microscopic machines called spliceosomes are hard at work.

13 May 2024

Understanding Genome Scrambling in Oikopleura Dioica

When two animals look the same, eat the same, behave the same way, and live in similar environments, one might expect that they belong to the same species.

10 May 2024

New Tool Precisely Edits Epigenetic Modifications

Powerful epigenetic editing technology was developed as a result of research by the Hackett group at EMBL Rome. This technology allows for the precise programming of chromatin modifications.

10 May 2024

mRNA Dynamics Guide Cell Identity Formation

New research from Hebrew University sheds light on the regulation of mRNA during the development of the embryo. The research separates newly-transcribed from pre-existing mRNA in zebrafish embryos using a combination of single-cell RNA-Seq and metabolic labeling.

8 May 2024

Herpesvirus Infection Reshapes Mitochondrial Architecture and Disrupts Metabolic Processes

Herpesvirus infection alters the host cell's mitochondria's normal structure and function, according to researchers from the University of Jyväskylä.

8 May 2024

Protein Complex Movement May Regulate Cell Division, Impacting Disease Research

Scientists at Umeå University in Sweden have found that the movement of a unique protein complex known as the Mediator along DNA genes may affect the process of cell division.

6 May 2024

St. Jude Scientists Reveal Role of Non-Coding DNA Variants in Childhood Leukemia

St. Jude Children's Research Hospital scientists have identified specific DNA variants in the non-coding regions of the genome contributing to chemotherapy resistance in acute lymphoblastic leukemia (ALL).

2 May 2024

Investigating Enhancer Function in Pluripotent Stem Cells

As embryos, all complex organisms are partially made up of pluripotent stem cells, a term for cells that have the capacity to differentiate into any kind of cell: nerve cells, muscle cells, blood cells, skin cells, and the like.

30 Apr 2024

Study Uncovers Cells' Surprising Strategy to Control Signaling Pathways

Healthy cells respond appropriately to changes in their environment. They do this by sensing what's happening outside and relaying a command to the precise biomolecule in the precise domain that can carry out the necessary response.

23 Apr 2024

Cellular Atlas of the Human Ovary Offers Hope for Restoring Hormone Production and Fertility

A new "atlas" of the human ovary provides insights that could lead to treatments restoring ovarian hormone production and the ability to have biologically related children, according to University of Michigan engineers.

9 Apr 2024

New Tool Predicts How Proteins Interact with RNA Structures

Scientists at the Italian Institute of Technology and Aarhus University have figured out how specific proteins can bind to G-quadruplexes, which are unique RNA structures.

4 Apr 2024

The Influence of sRNA on Gut Pathogen Drug Susceptibility

A significant breakthrough in understanding how gut bacteria adapt to their environment.

26 Mar 2024

Researchers Unveil Simple Trick to Improve Accuracy Of Plant Genetics Research

Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables – such as temperature – affect gene activity in plants.

14 Mar 2024

The Evolution of Plant Cell Analysis with RevGel-seq Technique

Plant cell analysis has been completely transformed by recent advances in single-cell RNA sequencing (scRNA), such as the recently created “RevGel-seq” technique.

13 Mar 2024

Study Identifies Protein Key to Preserving Neuronal Identity

Epigenetic processes allow different cell types to emerge from a single genome. Throughout development, cells differentiate and acquire distinct characteristics by expressing the same genome in different ways.