Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Imaging technique could replace invasive tissue biopsies to determine cancer drug resistance

Imaging techniques could replace the need for invasive tissue biopsies in helping rapidly determine whether cancer treatments are working effectively, according to researchers at the University of Cambridge.

7 Oct 2020

Biomarker for diagnosis of neurodegenerative diseases identified in the eye

A new study led by Boston Medical Center researchers indicates a well-known biomarker that serves as a marker for earlier diagnosis of neurodegenerative diseases is now detectable in the eye.

24 Sep 2020

In-depth study of kidney tumors reveals novel markers of response to immunotherapy

Treatments for kidney cancer have improved considerably over the past few decades. In 1988, when Memorial Sloan Kettering oncologist Robert Motzer started researching the disease, the average survival was less than one year.

9 Sep 2020

Elevated levels of heart failure marker increase risk for diabetes-related complications

Healthy people - especially women - with elevated levels of the heart failure marker NT-proBNP have a lower risk of developing type 2 diabetes.

19 Aug 2020

LJI scientists tracked down rare stem cells that generate neutrophils in humans

Neutrophils are the warriors of the immune system. They are always ready to spring to action to help heal injuries or fight off disease. Unless, that is, something goes wrong in their developmental process.

19 Aug 2020

Long-term opioid use in back-pain patients leads to production of anti-opioid antibodies

University of Wisconsin-Madison scientists have discovered that a majority of back-pain patients they tested who were taking opioid painkillers produced anti-opioid antibodies.

19 Aug 2020

Detection of cancer using different kind of liquid biopsy

Because cancer is easier to successfully treat when it's caught early, a major goal in cancer research is to develop new ways to find tumors at early stages, before they start to spread. One approach that's being studied are liquid biopsies.

14 Aug 2020

A genetic link discovered to predict treatment response for patients with rare, aggressive cancer

A Singapore team led by clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) discovered a genetic link to better predict treatment response for relapsed/refractory patients with natural- killer T-cell lymphoma (NKTCL), a highly aggressive form of blood cancer.

13 Aug 2020

Exercise induces changes in sweat biomolecule levels, shows study

A new study shows that in addition to blood, endurance exercise induces changes in sweat biomolecule levels. These findings lay the groundwork for the development of future noninvasive exercise monitoring systems that utilize sweat as a biomarker source.

13 Aug 2020

Enzyme in the gut could provide a useful biomarker for intestinal diseases

Enzymes used by bacteria to break down mucus in the gut could provide a useful biomarker for intestinal diseases, according to new research published in Nature Communications.

12 Aug 2020

New technology captures common biomarker of heart-disease

Researchers at the University of Wisconsin-Madison have developed a method combining sticky nanoparticles with high-precision protein measurement to capture and analyze a common marker of heart disease to reveal details that were previously inaccessible.

7 Aug 2020

Newly discovered biomarkers predict response to immunotherapy in Type 1 diabetes

Scientists at UCL have discovered new biomarkers, which may identify those people with Type 1 diabetes who would benefit from the immunotherapy drug Abatacept, a finding which could eventually help thousands manage the disease more effectively.

From University College London 4 Aug 2020

Novel measurement technology may open up new potentials in personalized medicine

Similar to blood sugar, various biomarkers could in future be identified using just a few drops of blood. Researchers at Ruhr-Universität Bochum are developing a multi-analyte test strip for this purpose that will open up new potentials in personalized medicine by facilitating the continuous measurement of various parameters.

29 Jul 2020

Researchers identify phosphoprotein biomarkers to guide cancer therapy

Precision medicine in cancer treatment uses genetic changes in the cancer cells to select the best therapies for individual patients.

29 Jul 2020

Epigenomic data can help characterize genes that play key role in cancer progression

As cancer cells evolve, many of their genes become overactive while others are turned down. These genetic changes can help tumors grow out of control and become more aggressive, adapt to changing conditions, and eventually lead the tumor to metastasize and spread elsewhere in the body.

From Massachusetts Institute of Technology (MIT) 24 Jul 2020

Researchers identify a potential biomarker of aging

The skin is the only organ that shows age more profoundly. While researchers have hypothesized about the ravages of time on skin and also the epidermal stem cells that undergo differentiation to restore the external layer of the skin, no suitable method is available to assess their aging at the molecular level.

22 Jul 2020

Gene biomarker can distinguish between atopic dermatitis and psoriasis with 100% accuracy

Mount Sinai researchers have pinpointed a single gene biomarker, nitride oxide synthase 2 (NOS2) that can distinguish atopic dermatitis (AD) and psoriasis with 100 percent accuracy using adhesive tape strips, a non-invasive alternative to skin biopsy.

22 Jul 2020

Simple blood test could advance life-saving treatment for heart failure

Biomedical experts believe that half of heart failure patients likely have low levels of the thyroid hormone T3 in their cardiac tissue.

20 Jul 2020

Researchers develop novel technology to detect cancer biomarkers

A new way of identifying cancer biomarkers has been developed by researchers at Lund University in Sweden. The new technology allows very sensitive, quick and cost-effective identification of cancer biomarkers. The research is published in Nature Communication Biology.

16 Jul 2020

Combination of western-style high-fat diet with antibiotic can increase the risk of pre-IBD

Researchers have found that combining a Western-style high-fat diet with antibiotic use significantly increases the risk of developing pre- inflammatory bowel disease.

16 Jul 2020

Biomarker News and Research

Imaging technique could replace invasive tissue biopsies to determine cancer drug resistance

Biomarker for diagnosis of neurodegenerative diseases identified in the eye

In-depth study of kidney tumors reveals novel markers of response to immunotherapy

Elevated levels of heart failure marker increase risk for diabetes-related complications

LJI scientists tracked down rare stem cells that generate neutrophils in humans

Long-term opioid use in back-pain patients leads to production of anti-opioid antibodies

Detection of cancer using different kind of liquid biopsy

A genetic link discovered to predict treatment response for patients with rare, aggressive cancer

Exercise induces changes in sweat biomolecule levels, shows study

Enzyme in the gut could provide a useful biomarker for intestinal diseases

New technology captures common biomarker of heart-disease

Newly discovered biomarkers predict response to immunotherapy in Type 1 diabetes

Novel measurement technology may open up new potentials in personalized medicine

Researchers identify phosphoprotein biomarkers to guide cancer therapy

Epigenomic data can help characterize genes that play key role in cancer progression

Researchers identify a potential biomarker of aging

Gene biomarker can distinguish between atopic dermatitis and psoriasis with 100% accuracy

Simple blood test could advance life-saving treatment for heart failure

Researchers develop novel technology to detect cancer biomarkers

Combination of western-style high-fat diet with antibiotic can increase the risk of pre-IBD

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