Microscopy

Microscopy is an umbrella term to describe techniques used to analyse small samples that cannot be viewed with the naked eye. There is a wide range of microscopy techniques and scientific instruments available that can be used depending on their applications. A microscope magnifies tiny objects or samples and can provide a wealth of vital information about their cell structure, contamination, parasites and so much more.

This hub will contain all of the information you need to know about microscopy and will include the latest news and fascinating research articles. Whether you are looking to expand your knowledge of compound microscopes or fluorescence microscopy, you will find it all here under featured articles and the latest interviews.

What is Microscopy?

The word microscope is derived from the Greek “mikros”, meaning small and, “skopein” meaning to see.

Microscopy and Artificial Intelligence

Scanning Electron Microscopy (SEM): An Overview

Investigating the Intersection between Microscopy and Healthcare

Fluorescence Microscopy: An Overview

Using Scanning Electron Microscopy to Image SARS-CoV-2

Confocal Microscopy: An Overview

Electron Microscopy: An Overview

Using Electron Microscopy to Detect Viruses

Applications of Scanning Electron Microscopy

Uses of Microscopy in Forensics

What are Polarized Light Microscopes and How Do They Work?

See more featured articles »

Role of Microscopy in Ballistics

Applications of Polarized Light Microscopy

Phase-Contrast Microscopy: An Overview

Avoiding Cell Death in Fluorescence Microscopy

Photobleaching in Fluorescence Microscopy

TEM Imaging Modes

Visualizing the 3D Architecture of Tissues

What is Confocal Imaging?

The Determination of Post-Mortem Interval (PMI) Using Transmission Electron Microscopy

The Digital Evolution of Microscopy

What is FIB-SEM?

‘Staining’ of Biological Samples when Using Electron Microscopy: Why stain density matters

Why Size Matters in Microscopy

Light Microscopy Techniques in Virology: An Overview

Identifying Corpses Using Microscopy

What is Environmental Forensic Microscopy?

Imaging Techniques in Drug Discovery

Microscopy and Artificial Intelligence

Deep Learning in Fluorescence Microscopy

Optimizing Live Cell Imaging with FRET Microscopy

‘Staining’ of Biological Samples when Using Electron Microscopy: Why stain density matters

Applications of IVIS (In Vivo Imaging Systems)

Advances in Scanning Electron Microscopy

Microscopes in Forensic Epidemiology- An Overview

What is 3D X-Ray Microscopy?

TEM Imaging Modes

Imaging Nuclear Structures Using AFM

Advances in Fluorescence Microscopy

Cryo-Electron Microscopy: An Overview

Confocal Reflection Microscopy for Cell Migration Studies

Transmission Electron Microscopy: An Overview

How do Epifluorescence Microscopes Work?

What is High-Resolution TEM (HR-TEM)?

Applications of 3D X-ray Microscopy

Two-photon Microscopy Principles and Methodology

Advantages and Limitations of Fluorescence Microscopy

Optical Microscopy: An Overview

Light Microscopy Techniques in Virology: An Overview

Optimizing Live Cell Imaging with FRET Microscopy

Using Microscopy for Deep In Vivo Brain Imaging

Microscopy’s Involvement in Brain Imaging

Differentiating Tumors using Microscopy

Expansion Microscopy in Neurology

Scanning Helium Microscopy: An Overview

X-ray Microscopy: An Overview

Diagnosing Alzheimer's Using Microscopy

Intravital Kidney Microscopy: An Overview

Investigating the Applications of Meoscopy

What is Expansion Microscopy?

Live-Cell Imaging with Super-Resolution Microscopy

Understanding the Brain Through Electron Microscopy

How Do Spectrometer Accessories Elevate Instrument Capabilities?

Microscopy in Oncology Research: Visualizing Tumor Microenvironments

Latest Microscopy News and Research

Cell Painting Technology Reveals Potential Cancer-Fighting Flavonoids

A team led by researchers at Baylor College of Medicine has identified flavonoids, natural compounds found in plants, that are toxic to bladder cancer cells cultured in the lab.

21 May 2025

Molecular Mechanism Revealed by Stop-Motion Electron Microscopy

Using electron microscopy, researchers illustrate FusB's role in antibiotic resistance, providing a molecular-level understanding of fusidic acid interactions.

19 May 2025

Visualizing Intracellular Molecular Landscapes in Single Cells

The t-SPESI method enables real-time visualization of intracellular lipids, offering insights into disease mechanisms and improving diagnostic tool development.

15 May 2025

Microscopy Study Uncovers Dynamic Brain Remodeling During Hormonal Cycles

Hormone levels fluctuate like the tides, ebbing and flowing according to carefully orchestrated cycles.

14 May 2025

Haematococcus pluvialis Microalga-Derived Nanoparticles Offer Eco-Friendly Boost for Plant Growth and Seed Priming

Algae-derived nanoparticles from Haematococcus pluvialis enhance maize seed growth and microbial health, offering a green solution for sustainable agriculture.

13 May 2025

Cryo-EM Reveals Protein-Free RNA Structures in Bacterial Cells

Cryogenic electron microscopy showed for the first time that large RNA complexes can assemble without the help of proteins, expanding our understanding of RNA folding and function.

10 May 2025

Novel Molecule Inducing Ferroptosis for Metastatic Cancer Therapy

Scientists from Institut Curie, the CNRS, and Inserm have just created a novel class of molecules capable of destroying cancer cells that are resistant to current treatments and cause recurrence.

8 May 2025

Restoring Alpha-Synuclein to Support Synaptic Function and Neurotransmission

A new study reveals how restoring α-synuclein levels can help preserve synaptic vesicle composition and function, offering therapeutic insights for Parkinson’s and other neurodegenerative diseases.

7 May 2025

3D Printing Collagen Scaffolds with Perfusable Systems for Tissue Engineering

Scientists have developed high-resolution 3D-printed collagen scaffolds with internal perfusion systems, enabling complex, vascularized tissue models that support cell viability, growth, and insulin secretion

6 May 2025

New Neural Circuit Discovery Explains Precision Steering in Fruit Flies

When a fruit fly is navigating straight forward at high speed, why does it know that it's not straying off course? Because as long as the fly moves directly forward, the visual scene shifts from front to back in a near-perfect mirror image across both retinas – generating, in other words, a symmetrical visual motion pattern.

2 May 2025

Can Cells Hear? Study Finds Sound Alters Gene Activity and Blocks Fat Cell Development

Acoustic stimulation affects cell development and gene activity, revealing potential applications in biotechnology and obesity control through sound waves.

24 Apr 2025

Study Reveals Direct Impact of Sound on Cellular Activity

The intense feeling one gets from powerful sounds, like a jet engine at takeoff or booming concert speakers, is not just in the head and ears – the cells might be sensing it too.

17 Apr 2025

Revealing Noise-Filtering in Basic Circadian Networks

New research has revealed that a simple circadian clock network possesses advanced noise-filtering capabilities, which improves the understanding of how biological circuits maintain accuracy in dynamic environmental contexts.

16 Apr 2025

Novel Microscopy Reveals Two-Stage T-Cell Activation During Viral Infection

The research teams led by Wolfgang Kastenmüller and Georg Gasteiger utilized advanced microscopy techniques to investigate the activation and proliferation of specific immune cells, known as T-cells, during viral infections.

11 Apr 2025

Unraveling the Interaction Between Mitochondrial Proteins HAX1 and CLPB

A recent study published in Magnetic Resonance Letters has revealed for the first time the interaction mechanism between the mitochondrial proteins HAX1 and CLPB, filling the research gap between these two key proteins in the field of structural dynamics and functional association.

10 Apr 2025