Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

What is Western Blotting?

Challenges in Environmental Metabolomics

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

Understanding Native Protein Characterization

Racial Differences in Protein Biomarkers

Protein Production: Initiation, Elongation and Termination

Heritability Differences in Metabolic Classes

Role of Proteomic Analysis in Skin Regeneration

What is Phosphoproteomics?

Ethics in Clinical Proteomics

What is Protein Ubiquitylation?

See more featured articles »

What is the Metabolome?

Applications of Peptidomics

Using Omics to Harness the Power of Personalized Nutrition

What are Prions?

How Can Proteins Help Organisms to Tell the Time?

Insight into the Human Proteoform Project

Studying the Metabolic Pathways Between Tissues

How to Analyze Macromolecular Protein Complexes

Metabolomics in Toxicology

What is Clinical Proteomics?

Importance of Solubility and Lipophilicity in Drug Development

Environmental Metabolomics

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Discovering Misfolded Proteins using Fluorescent Probes

An Overview of Protein Localization

An Overview of Quantitative Proteomics

How do we Radiolabel Proteins?

Role of Applied Omics in Precision Medicine

The Role of Metabolomics in Precision Medicine

Compound Identification for Nontargeted Metabolomics

What are G-Protein-Coupled Receptors?

Omics Approaches to Biomarker Analysis

What is 'Bottom-Up' Proteomics?

A Guide to Optimizing Protein Design

What is Pharmacometabolomics?

Eliminating American Foulbrood using Endolysins

Understanding Neurobiology through Proteins

Analyzing Proteomes Using LC-MS/MS

Applications of Bone Proteomics

Cytometric Bead Arrays: A Breakdown of the Technique

Protein Degradability

What is Single-Cell Proteomics?

Pharmacokinetics of Cannabis and its Secondary Metabolites

Challenges in Metabolomic Fingerprinting

Combating Counterfeit Green Tea with Metabolomic Profiling

Effects of Filtered Coffee on Plasma Metabolites

What is Forensic Proteomics?

How have Fluorescent Proteins Transformed Science?

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Combating Infectious Diseases Through Computational Protein Design

Investigating the Evolution of Microbiome Science

What is 4D Proteomics?

Interpreting Proteomics Data

A Beginners Guide to Plasma Proteomics

What Role do Proteins Play in Disease?

Compound Identification for Nontargeted Metabolomics

Protein Biosynthesis

The ‘omics’ Revolution

How are the Metabolome and Proteome Related?

Determining Proteins in Milk Using Dumas Analysis

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Challenges with Standardization in Lipidomics

The Steps of Protein Synthesis

How is Omics Revolutionizing Cancer Research?

How does the Proteome Differ Between Individuals?

What is Phenomics?

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Global Market Overview: Metabolomics

The Human Metabolome Project

What is Metabolomics?

What is Proteomics?

Importance of Lipidomics in Stem Cell Research

Combining Proteomics and Genomics to Eliminate Disease

Liver Disease Biomarkers

Lipidomics in Food Science

What is Shotgun Lipidomics?

Exploring Biosynthetic Diversity

What is Immunoliposome Therapy?

Role of Proteomics in COVID-19

Latest Proteomics, Metabolomics and Lipidomics News and Research

New Research Challenges the Static View of Chromosome Shape

An international team of researchers from the Francis Crick Institute, Imperial College London, Waseda University, and the Cancer Institute of the Japanese Foundation for Cancer Research has reshaped the concept of chromosome shape, discovering that they are not always stable X-shaped structures but are constantly in flux as cell division occurs.

24 Sep 2025

Targeting Two Key Proteins to Weaken Pancreatic Cancer's Defenses

Indiana University School of Medicine scientists have identified a new way to weaken pancreatic cancer's defenses by targeting two key proteins that help the deadly disease resist treatment.

22 Sep 2025

Metabolic Signals Shape the Rhythm of Embryonic Segmentation

Pregnant women rely on a balanced diet and supplements to deliver proper nutrients to their babies, to ensure they grow healthfully.

22 Sep 2025

Editing SlVI Gene Enhances Sugar Content and Disease Resistance in Tomato Fruit

Tomato fruit development relies on complex sugar metabolism, including the conversion of stored starch into sucrose, glucose, and fructose.

22 Sep 2025

Integrative Genomic Approaches Reveal Mechanisms of Garlic Storability

Garlic (Allium sativum L.) is one of the world's most widely consumed spices and health supplements, with China producing 80% of the international supply.

22 Sep 2025

Study Uncovers the Molecular Basis of Synapse Development

A team of scientists from the University of Cologne’s Institute of Biochemistry has discovered a significant finding about the molecular basis of synapse development in the central nervous system.

22 Sep 2025

Modified Cas9 Proteins Dramatically Lower Error Rates in Prime Editing

A genome-editing technique known as prime editing holds potential for treating many diseases by transforming faulty genes into functional ones.

18 Sep 2025

Carbon Starvation Drives Metabolic and Epigenetic Reprogramming in Grapevine Cells

Plants rely on sugars not only as energy sources but also as regulators of cellular activities. Carbon starvation disrupts central metabolism, impairs growth, and forces cells to recycle stored resources.

18 Sep 2025

The First Parent-Of-Origin Gene Atlas of The Mammary Gland

This study maps dynamic gene expression in mouse mammary glands, revealing insights into lactation, maternal health, and breast cancer risk through imprinting.

18 Sep 2025

Tracing Evolutionary Roots of the Genetic Code

Genes are the building blocks of life, and the genetic code provides the instructions for the complex processes that make organisms function.

17 Sep 2025

Unique Cytochrome Protein Holds Key to Plant Survival and Metabolism

Despite their fundamental differences, plants, animals, and fungi share certain metabolic processes.

17 Sep 2025

Reconstructing Human Mitochondrial Transcription in Unprecedented Detail

Aging, neurological diseases and our bodies' stress response are all linked to the tiny power plants inside each cell known as mitochondria.

17 Sep 2025

CRISPR Breakthrough Makes Cacao Plants More Resistant To Deadly Disease

This study shows CRISPR-Cas9 modifications to the TcNPR3 gene in cacao reduce Phytophthora susceptibility, supporting eco-friendly agricultural practices.

17 Sep 2025

Microarray Profiling Identifies LINC00974 as a Sensitive Marker for Breast Cancer Risk

In the post-genomic era, long non-coding RNAs (lncRNAs) have emerged as critical regulators in various cancers and hold potential as minimally invasive diagnostic biomarkers.

16 Sep 2025

Soil DNA Reveals Hundreds of Unknown Bacterial Genomes

Most bacteria cannot be cultured in the lab-and that's been bad news for medicine. Many of our frontline antibiotics originated from microbes, yet as antibiotic resistance spreads and drug pipelines run dry, the soil beneath our feet has a vast hidden reservoir of untapped lifesaving compounds.

16 Sep 2025

Study Reveals Stabilizing Effect of Small Molecules on Proteins

For decades, amino acids have been added to medical formulations like insulin as stabilizers: these small molecules keep proteins (i.e. larger particles) from interacting in undesirable ways.

16 Sep 2025

Microbial Molecule Controls Cancer Progression and Boosts Chemotherapy

An international team of scientists led by researchers from the MRC Laboratory of Medical Sciences (LMS), Imperial College London, and the University of Cologne discovered that microbes associated with tumors produce a molecule that can control cancer progression and improve chemotherapy efficacy.

15 Sep 2025

A Molecular Magnifying Glass for Tracking Protein Misfolding in Living Cells

A novel strategy developed at Rice University allows scientists to zoom in on tiny segments of proteins inside living cells, revealing localized environmental changes that could indicate the earliest stages of diseases such as Alzheimer's, Parkinson's and cancer.

15 Sep 2025

Researchers Decipher the Rules Behind Cellular Quality Control In Humans

A research team at the University of Cologne and the Max Delbrück Center in Berlin has deciphered in detail the rules behind an important mechanism of cellular quality control in humans.

13 Sep 2025

Electrical Jolt Speeds Fermentation of Food Waste into Valuable Chemicals

Adding an electrical jolt to fermentation of industrial food waste speeds up the process and increases the yield of platform chemicals that are valuable components in a wide range of products, new research shows.

13 Sep 2025