Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

Global Market Overview: Metabolomics

What is Proteomics?

What is Single-Cell Proteomics?

Racial Differences in Protein Biomarkers

Combining Proteomics and Genomics to Eliminate Disease

Using Omics to Harness the Power of Personalized Nutrition

How is Omics Revolutionizing Cancer Research?

Insight into the Human Proteoform Project

Omics Approaches to Biomarker Analysis

The Role of Metabolomics in Precision Medicine

The Human Metabolome Project

See more featured articles »

Role of Applied Omics in Precision Medicine

What is Metabolomics?

Challenges with Standardization in Lipidomics

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Ethics in Clinical Proteomics

Applications of Peptidomics

How do we Radiolabel Proteins?

What is Clinical Proteomics?

Understanding Native Protein Characterization

What is 'Bottom-Up' Proteomics?

What is Shotgun Lipidomics?

A Beginners Guide to Plasma Proteomics

Lipidomics in Food Science

Protein Biosynthesis

What are Prions?

Challenges in Environmental Metabolomics

Discovering Misfolded Proteins using Fluorescent Probes

Compound Identification for Nontargeted Metabolomics

Combating Infectious Diseases Through Computational Protein Design

What is Forensic Proteomics?

Eliminating American Foulbrood using Endolysins

Environmental Metabolomics

How are the Metabolome and Proteome Related?

Importance of Lipidomics in Stem Cell Research

Interpreting Proteomics Data

What Role do Proteins Play in Disease?

Metabolomics in Toxicology

What is 4D Proteomics?

What is Phosphoproteomics?

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

What is Protein Ubiquitylation?

What is the Metabolome?

Applications of Bone Proteomics

What are G-Protein-Coupled Receptors?

A Guide to Optimizing Protein Design

Determining Proteins in Milk Using Dumas Analysis

Role of Proteomic Analysis in Skin Regeneration

An Overview of Protein Localization

Liver Disease Biomarkers

What is Pharmacometabolomics?

Protein Degradability

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Analyzing Proteomes Using LC-MS/MS

Challenges in Metabolomic Fingerprinting

The Steps of Protein Synthesis

Effects of Filtered Coffee on Plasma Metabolites

How have Fluorescent Proteins Transformed Science?

Compound Identification for Nontargeted Metabolomics

Combating Counterfeit Green Tea with Metabolomic Profiling

Protein Production: Initiation, Elongation and Termination

What is Phenomics?

Importance of Solubility and Lipophilicity in Drug Development

How does the Proteome Differ Between Individuals?

What is Immunoliposome Therapy?

Heritability Differences in Metabolic Classes

Exploring Biosynthetic Diversity

Pharmacokinetics of Cannabis and its Secondary Metabolites

Understanding Neurobiology through Proteins

The ‘omics’ Revolution

How Can Proteins Help Organisms to Tell the Time?

Role of Proteomics in COVID-19

An Overview of Quantitative Proteomics

What is Western Blotting?

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Studying the Metabolic Pathways Between Tissues

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Investigating the Evolution of Microbiome Science

How to Analyze Macromolecular Protein Complexes

Cytometric Bead Arrays: A Breakdown of the Technique

Latest Proteomics, Metabolomics and Lipidomics News and Research

Waters Acquires Halo Labs, Expanding Biological Analysis Portfolio

Waters Corporation today announced that it has acquired Halo Labs™, an innovator of specialized imaging technologies to detect, identify, and count interfering materials (particles) in therapeutic products, such as cell, protein, and gene therapies.

23 May 2025

Scientists Develop Method to Overcome Key Limitations of Cryo-EM

Sample loss has been a persistent problem in cryo-EM, a high-tech method for creating 3D models of molecules that reveals their inner structures.

22 May 2025

New Bacterial Consortium can Inhibit Bacterial Pathogens in Aquaculture

A new study by Danish researchers has demonstrated that it is possible to develop a consortium of bacteria that can inhibit bacterial pathogens in aquaculture.

22 May 2025

Unraveling the Co-Evolution of Human Height and Basal Metabolic Rate

Taller stature and a higher basal metabolic rate are two characteristics that distinguish modern humans from non-human primates. A genetic variant that helped these traits co-evolve was discovered by researchers and published in Cell Genomics.

22 May 2025

Cell Painting Technology Reveals Potential Cancer-Fighting Flavonoids

A team led by researchers at Baylor College of Medicine has identified flavonoids, natural compounds found in plants, that are toxic to bladder cancer cells cultured in the lab.

21 May 2025

Study Unveils Molecular Mechanism Behind Synapse Maturation

Researchers from the lab led by Prof. Joris De Wit (VIB-KU Leuven) have discovered an important clue to how connections between brain cells, known as synapses, mature.

21 May 2025

Compression Drives Aggressive Behavior in Liver Cancer Cells

Yale researchers are providing new insights into how physical forces, such as cells being compressed in physically restrictive environments, play key roles in cancer progression.

21 May 2025

TEAD Proteins Switch Partners to Drive Neural Cell Maturation

The basic mechanisms that control neural development are intricate, and as research from St. Jude Children's Research Hospital shows, the underlying motivations may even seem contradictory.

21 May 2025

Tracing the Evolution of Cyanobacterial Circadian Clocks Through Earth's History

Investigating ancient cyanobacterial timekeeping systems sheds light on the evolution of circadian rhythms and their significance in Earth's ecosystems.

21 May 2025

Zebrafish Study Warns of Ecological Risk from Tire-Related Water Contaminants

Emerging contaminants from rubber tires N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its oxidation product 6PPD-quinone (6PPDQ)-are raising new red flags for aquatic ecosystems.

20 May 2025

Autophagy: A Double-Edged Sword in Cancer and Protein Conformational Disorders

A new FEBS Letters review explores the dual role of autophagy in cancer and protein misfolding diseases—highlighting its potential as a therapeutic target and the challenges of tipping the balance between protection and harm.

20 May 2025

Trace the Evolution of Malaria Parasite Proteins

Researchers at the Francis Crick Institute and the Gulbenkian Institute for Molecular Medicine (GIMM) have discovered that the evolution of a family of exported proteins in the malaria-causing parasite Plasmodium falciparum allowed it to infect people.

20 May 2025