To ensure that medical genetic research better represents and benefits people from all backgrounds, researchers at the University of Florida are filling a crucial gap in the field.

11 Mar 2025

Cryo-EM Reveals 3D Structure of Nipah Virus RNA Polymerase

The replication of the Nipah virus's genetic material in infected cells has been demonstrated for the first time by researchers from the Max Planck Institute (MPI) for Multidisciplinary Sciences and the University Medical Center Göttingen (UMG). In humans, the virus can cause fatal encephalitis.

11 Mar 2025

‘Rescue’ Mutations Protect Liver From Damage in Patients With Genetic Disorder

Acquired DNA mutations found in the SERPINA1 gene can protect liver cells from damage in patients with alpha-1 antitrypsin deficiency, new research shows.

11 Mar 2025

Sulfate-Reducing Bacteria Play Key Role in Global Carbon Breakdown

Sulfate-reducing bacteria break down a large proportion of the organic carbon in oxygen-free zones of the Earth, and in the seabed in particular.

10 Mar 2025

Rare ITSN1 Gene Variants Found to Significantly Elevate Parkinson's Risk

A new study published in Cell Reports reveals a breakthrough discovery linking genetic variants in the gene ITSN1 to a significantly elevated risk of Parkinson's disease, a neurodegenerative condition that affects nearly 2% of adults older than 65 years.

10 Mar 2025

Circular RNA's Transformative Role in Tumor Biology and Treatment

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

10 Mar 2025

Investigating Ubiquitination's Role in Cancer Stem Cell Regulation

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, recurrence, and drug resistance.

10 Mar 2025

$30 Million Grant Supports AI-Powered Antibody Therapy Development

An ambitious project led by Vanderbilt University Medical Center investigators aims to use artificial intelligence technologies to generate antibody therapies against any antigen target of interest.

10 Mar 2025

Mice Exhibit Altruistic Actions Towards Injured Companions

Humans are not the only species that may assist their injured companions; mice might exhibit similar behaviors, as demonstrated by a recent study conducted by researchers at the Keck School of Medicine of USC and published in Science.

10 Mar 2025

Low-Cost, Flexible Protein Detection Platform for Global Health

Chemical and biomolecular engineers at Georgia Tech have created a plug-and-play platform for the detection of disease protein biomarkers that is straightforward, adaptable, and user-friendly, eliminating the need for expensive laboratory equipment.

10 Mar 2025

Novel Expansion Microscopy Technique for Detailed Plant Biomolecule Mapping

The approach to studying plant cells is evolving quite literally due to new research led by Kevin Cox, an Assistant Professor of Biology in Arts & Sciences at Washington University in St. Louis and an Assistant Member of the Donald Danforth Plant Science Center.

10 Mar 2025

Cellular Changes as Lung Damage Worsens During COVID-19 Revealed

Changes in the cellular response during lung damage caused by SARS-CoV-2 – the virus behind COVID-19 – have been uncovered.

10 Mar 2025

Protective ‘Slime’ In The Brain May Help Prevent Aging And Neurodegeneration

The study shows that boosting mucin-type O-glycosylation in aged mice reinforces the blood-brain barrier and improves memory, paving the way for new treatments.

10 Mar 2025

Lack of Genetic Diversity in Reference Groups Leads to Misdiagnoses

A new study has uncovered that a gene variant common in Oceanian communities was misclassified as a potential cause of heart disease, highlighting the risk of the current diversity gap in genomics research which can pose a greater risk for misdiagnosis of people from non-European ancestries.

8 Mar 2025

Genomics can Transform Care for Children with Rare Diseases

A simple genomics blood test could improve treatment and care for childhood epilepsy, but more investment is needed to make access fair and securely join up the data, finds a new study involving researchers at University College London (UCL) and Great Ormond Street Hospital for Children (GOSH).

8 Mar 2025

Study Reveals How the Brain Reorganizes Sensory Maps After Loss of Touch

A team of researchers from the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and Miguel Hernández University (UMH) in Elche, has discovered that the developing brain can reorganize its sensory maps when the sense of touch is affected.

8 Mar 2025

Study Shows How Transposons Exploit Telomeres in Bacteria

Transposons, or "jumping genes" – DNA segments that can move from one part of the genome to another – are key to bacterial evolution and the development of antibiotic resistance.

8 Mar 2025

Structural Insights into uMtCK Offer New Pathways for Targeting Cancer Energy Mechanisms

Cancer cells have an insatiable appetite for energy as they multiply more rapidly than normal cells. Greedy cancer cells hijack various cellular functions to find and exploit energy and other resources, including a group of enzymes that help normal cells maintain a balance of energy.

8 Mar 2025

DENND1B Gene Linked to Obesity in Dogs and Humans

Dogs are a compelling model of human obesity, in part because they develop obesity due to similar environmental influences as people.

8 Mar 2025

New Brain-Mapping Technique Pinpoints Cell Types Linked to Alzheimer's Progression

Researchers from The University of Texas at Arlington and the University of California–San Francisco have employed a novel brain-mapping technique to pinpoint memory-related brain cells that are susceptible to protein accumulation, a significant contributor to the onset of Alzheimer’s disease, an irreversible and progressive neurological disorder that gradually impairs memory and cognitive abilities.

7 Mar 2025