Microscopy News and Research

Latest Microscopy News and Research

Novel Anti-CRISPR Protein Targets Cas13b RNA Nuclease

There are numerous potential uses for the CRISPR-Cas gene scissors, ranging from antiviral treatments and diagnostics to the treatment of genetic disorders.

18 Feb 2025

Researchers Discover New Role of Mitofusin 2 in Cellular Health

Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, protein quality control and cellular health, whose failure could be the leading cause in the currently incurable neurological disease Charcot-Marie-Tooth (CMT).

17 Feb 2025

Scientists Uncover Mechanism Linking OPN3 to Food Intake Regulation

Scientists discovered years ago that the hypothalamus - which helps to manage body temperature, hunger, sex drive, sleep and more - includes neurons that express the protein opsin 3 (OPN3).

17 Feb 2025

Computational Modeling Streamlines Antiviral Discovery

Viruses, such as those responsible for COVID-19 and HIV, present significant challenges once they enter the human body. Antiviral therapies aim to obstruct a virus or prevent its replication.

17 Feb 2025

Study Reveals Mechanisms Behind Bacterial Flagellar Motor Movement

When speaking of motors, most people think of those powering vehicles and human machinery. However, biological motors have existed for millions of years in microorganisms.

14 Feb 2025

How Bacteriophages Build a Protein-Based Nucleus to Outsmart Bacteria

Jumbo phages utilize a complex protein import system, with Imp1 as a key gatekeeper, to transport proteins into their protective nucleus-like compartment.

14 Feb 2025

New Research Sheds Light on How Cells Manage Fat Recycling

Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have made a breakthrough in understanding how our cells manage to stay healthy by recycling important fat molecules.

13 Feb 2025

Understanding the Complex Architecture of the Minor Spliceosome

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome continuously separates the coding and non-coding regions of our genes – and it's doing this even as you read these lines.

13 Feb 2025

New Study Reveals Energy-Saving Strategies in Neuronal Protein Synthesis

Nerve cells use incredible energy-saving techniques while still carrying out their primary functions.

10 Feb 2025

High-Resolution Images Reveal How Cells Discard Faulty Spliceosomes

A sophisticated molecular machine, the spliceosome, ensures the accurate assembly of genetic information from the genome into mature mRNA after it has been transcribed into mRNA precursors.

10 Feb 2025

Cryo-EM Uncovers Hidden Complexity in Collagen Structure

The most prevalent protein in the body, collagen, has long been thought to be a predictable structural element of tissues.

10 Feb 2025

Research Reveals Key Mitochondrial Role in Social Recognition Memory

Virginia Tech neuroscientists have uncovered a mitochondrial process that supports the brain cells critical for learning, memory, and social recognition.

10 Feb 2025

New Technology for Visualizing Gene Activity in Single Cells

How do bacteria whether harmless ones residing in human bodies or those causing diseases coordinate their activities?

6 Feb 2025

Nutrient Starvation Impedes Antibiotic Efficacy in Salmonella Infections

A new study from the University of Basel, published in Nature, challenges the conventional understanding of antibiotic treatment failure. Rather than attributing such failures to a small population of highly resistant bacteria, the research suggests a different explanation.

6 Feb 2025

Scientists Decode ApoB100 Structure for Targeted Heart Disease Treatments

Low-density lipoproteins (LDL) - commonly known as bad cholesterol - have long been on scientists' radar as a major contributor to heart disease.

4 Feb 2025

New Microscopy Technique Reveals Cancer's Metabolic Secrets

Understanding how tumors alter their metabolism to evade treatments is an increasingly important area of cancer research.

4 Feb 2025

Microscopy Technique Tracks Ribosome Activity

A novel microscopy method has been created by researchers from the Tanenbaum group at the Hubrecht Institute to view the activity of ribosomes in cells.

3 Feb 2025

New Protein Structures Could Lead to Better Treatments for Transthyretin Amyloidosis

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion.

29 Jan 2025

Fast and Precise Protein Labeling in Intact Tissues with MIT Technology

A new technology developed at MIT enables scientists to label proteins across millions of individual cells in fully intact 3D tissues with unprecedented speed, uniformity, and versatility.

27 Jan 2025

Unveiling the Architecture of Native NMDA Receptors in the Mammalian Brain

A research team led by Shujia Zhu from the Chinese Academy of Sciences’ (CAS) Center for Excellence in Brain Science and Intelligence Technology and Yang Li from the Shanghai Institute of Materia Medica of CAS examined the architecture and assembly of endogenous N-methyl-ᴅ-aspartate receptors (eNMDARs) in the cerebral cortex and hippocampus of adult mammals in a study published in Cell on January 23rd, 2025.

27 Jan 2025