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Identification of genetic variant provides a big step for precision medicine in dialysis

Every day, the human kidneys clean about 1,500 liters of blood by producing approximately 1–2 liters of urine. Thereby, the body gets rid of excess water and toxic waste products of the metabolism or also drugs and maintains the balance of water and minerals in the tissues.

21 Oct 2021

New biomarker can help characterize specific types of asthma and COPD

Rutgers researchers have discovered that people with asthma and chronic obstructive pulmonary disease have a protein in their lungs that leaks a small molecule into their bloodstream that restricts their breathing instead of relaxing their airways.

From Rutgers University 21 Oct 2021

Novel technique shows molecule conformations in live cells

Comprehending how proteins twist, bend, and shape-shift, as they work in cells, is vital to gain insights into diseases and normal biology.

21 Oct 2021

'Switching on' Sight using Gene Therapy

AZoLifeSciences speaks to Dr. Raymond Wong about his latest research into eye health and we could potentially 'switch on' sight using gene therapy.

20 Oct 2021

MIT researchers discover new way to awaken the immune system to attack tumors

Immunotherapy is a promising strategy to treat cancer by stimulating the body's own immune system to destroy tumor cells, but it only works for a handful of cancers. MIT researchers have now discovered a new way to jump-start the immune system to attack tumors, which they hope could allow immunotherapy to be used against more types of cancer.

From Massachusetts Institute of Technology (MIT) 20 Oct 2021

Study uncovers new gene variants that may cause inherited retinal dystrophies

An international team of researchers, led by scientists at University of California San Diego and Shiley Eye Institute at UC San Diego Health, has broadened and deepened understanding of how inherited retinal dystrophies (IRDs) affect different populations of people and, in the process, have identified new gene variants that may cause the diseases.

20 Oct 2021

Combining food science and computer programming to help the food industry stop Listeria outbreaks

Researchers from Cornell University are blending food science expertise and computer programming savvy to help the food industry stop Listeria outbreaks.

19 Oct 2021

Junk DNA' plays a crucial role in early embryonic development in all mammals, study shows

Nearly half of our DNA has been written off as junk, the discards of evolution: sidelined or broken genes, viruses that got stuck in our genome and were dismembered or silenced, none of it relevant to the human organism or human evolution.

19 Oct 2021

Neuroinflammation protein associated with sex-specific survival differences in glioblastoma patients

Scientists have discovered a new link that could bring the scientific and medical community closer to understanding why glioblastoma, the most common malignant brain tumor, is deadlier in males than females.

19 Oct 2021

Scientists reveal the importance of circadian rhythm on the immune system

Circadian clocks, which regulate most of the physiological processes of living beings over a rhythm of about 24 hours, are one of the most fundamental biological mechanisms.

19 Oct 2021

High tumor-infiltrating lymphocytes could indicate a better chance of survival in esophageal cancer

Cancerous tumors are made up of many more components than just malignant cells from the tissue of origin. Immune cells can be recruited to the tumor site and form what is known as the tumor microenvironment.

From Osaka University 19 Oct 2021

Study finds novel genes linked to fibromuscular dysplasia using genetic meta-analysis

Recent research identified that three novel genetic variants that control gene expression in the arteries are linked to fibromuscular dysplasia (FMD)—an arterial disease that induces threatening impacts for the heart and vessels.

19 Oct 2021

Study explains why shift workers are vulnerable to heart problems

Recent research demonstrates how circadian rhythms in heart cells help to change heart function.

19 Oct 2021

Study identifies highly potent monoclonal antibody against all SARS-CoV-2 variants

Researchers identified a greatly potent monoclonal antibody that aims at the spike protein of SARS-CoV-2.

19 Oct 2021

Novel research reveals a vital but previously unknown role for microglia

University of Virginia School of Medicine researchers have revealed a vital but previously unknown role for immune cells that protect the brain from disease and injury: The cells, known as microglia, also help regulate blood flow and maintain the brain's critical blood vessels.

18 Oct 2021

Researchers map proteo-genomic connections between different human diseases

Hundreds of connections between different human diseases have been uncovered through their shared origin in our genome by an international research team led by scientists from the Medical Research Council (MRC) Epidemiology Unit at the University of Cambridge, challenging the categorisation of diseases by organ, symptoms, or clinical speciality.

18 Oct 2021

Novel method enables quick identification of small active substance molecules

Secondary natural substances that occur in numerous plants, bacteria and fungi can be anti-inflammatory, can ward off pathogens or even prevent the growth of cancer cells. However, making use of the riches provided by nature's medicine cabinet and identifying new natural substances is time-consuming, costly and labour-intensive. A team of bioinformaticians at Friedrich Schiller University Jena has now developed a method that enables much faster and easier identification of small active substance molecules.

18 Oct 2021

AI-powered tool rapidly identifies genetic causes of rare disorders with high accuracy

An artificial intelligence (AI)-based technology rapidly diagnoses rare disorders in critically ill children with high accuracy, according to a report by scientists from University of Utah Health and Fabric Genomics, collaborators on a study led by Rady Children's Hospital in San Diego. The benchmark finding, published in Genomic Medicine, foreshadows the next phase of medicine, where technology helps clinicians quickly determine the root cause of disease so they can give patients the right treatment sooner.

From The University of Utah 18 Oct 2021

Researchers develop chimeric exosomes that co-activate immune response and tumor microenvironment

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have developed macrophage–tumor chimeric exosomes that co-activate the immune response and tumor microenvironment to support cancer immunotherapy.

18 Oct 2021

Brain immune cells take up large amounts of sugar at the beginning of neurodegenerative disease

At the beginning of neurodegenerative disease, the immune cells of the brain – the "microglia" – take up glucose, a sugar molecule, to a much greater extent than hitherto assumed.

18 Oct 2021

Medicine News and Research

Identification of genetic variant provides a big step for precision medicine in dialysis

New biomarker can help characterize specific types of asthma and COPD

Novel technique shows molecule conformations in live cells

'Switching on' Sight using Gene Therapy

MIT researchers discover new way to awaken the immune system to attack tumors

Study uncovers new gene variants that may cause inherited retinal dystrophies

Combining food science and computer programming to help the food industry stop Listeria outbreaks

Junk DNA' plays a crucial role in early embryonic development in all mammals, study shows

Neuroinflammation protein associated with sex-specific survival differences in glioblastoma patients

Scientists reveal the importance of circadian rhythm on the immune system

High tumor-infiltrating lymphocytes could indicate a better chance of survival in esophageal cancer

Study finds novel genes linked to fibromuscular dysplasia using genetic meta-analysis

Study explains why shift workers are vulnerable to heart problems

Study identifies highly potent monoclonal antibody against all SARS-CoV-2 variants

Novel research reveals a vital but previously unknown role for microglia

Researchers map proteo-genomic connections between different human diseases

Novel method enables quick identification of small active substance molecules

AI-powered tool rapidly identifies genetic causes of rare disorders with high accuracy

Researchers develop chimeric exosomes that co-activate immune response and tumor microenvironment

Brain immune cells take up large amounts of sugar at the beginning of neurodegenerative disease

Driving Support for Pharmaceutical Testing Through Continuous Innovation

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