Biomarker News and Research

RSS

A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Golgi membrane protein drives growth and invasion of breast cancer

The cover for issue 28 of Oncotarget features Figure 5, "TMEM165 expression levels alters N-linked glycosylation," by Murali, et al., and reported that the TMEM165 protein was not detected in non-malignant matched breast tissues and was detected in invasive ductal breast carcinoma tissues by mass spectrometry.

15 Jul 2020

New radiotracer provides a quantitative measure of disease progression after stroke

A new radiotracer, 18F-SynVesT-2, can directly assess synaptic density changes in the brain, providing an objective and quantitative measure of disease progression after stroke.

14 Jul 2020

Study shows cathepsin B can be used as biomarker for traumatic brain injury

Scientists at the Walter Reed Army Institute for Research (WRAIR) have recently demonstrated that cathepsin B, a well-studied protein important to brain development and function, can be used as biomarker, or indicator of severity, for traumatic brain injury.

14 Jul 2020

Discovery of novel mechanism associated with cancer could lead to new therapies

Cancer cases have been rising over the years and according to the statistics, the number of people living with cancer will continue to increase.

2 Jul 2020

Rapid genomic profiling of colon cancers can improve therapy

Genomic mutation testing is critical to the therapeutic selection and management of patients with colorectal cancer.

29 Jun 2020

MRI Scan Used For Heart Disease Could Also Pick Out Aggressive Cancers

An MRI scan used for heart disease could help assess whether children's cancers are especially aggressive and spot early signs that treatments are working.

29 Jun 2020

NJIT researchers develop new efficient method to quantify therapeutic proteins

Researchers at New Jersey Institute of Technology in collaboration with Ohio University and Merck & Co. Inc. recently developed a new efficient method for targeted protein analysis -- one they say could speed up processes for disease testing, drug discovery and vaccine development.

18 Jun 2020

Loss of lipid-regulating protein drives prostate cancer metastasis

Johns Hopkins Kimmel Cancer Center researchers from the Department of Radiation Oncology and Molecular Radiation Sciences identified a lipid-regulating protein that conveys what the researchers describe as "superpowers" onto prostate cancer cells, causing them to aggressively spread.

17 Jun 2020

Researchers identify a promising biomarker to screen stem cell quality

Published recently in the Stem Cells journal, a new study addresses a major issue that has been challenging the human mesenchymal stem cells (hMSCs) therapy.

9 Jun 2020

Study discovers race-specific lupus nephritis biomarkers for early diagnosis and treatment

Chandra Mohan, a Hugh Roy and Lillie Cranz Cullen Endowed Professor of biomedical engineering at the University of Houston, and his colleagues have identified a race-specific variance in the urinary biomarker proteins of lupus nephritis (LN) in patients.

6 May 2020

A groundbreaking tool for efficient lipid analysis

Scientists are increasingly aiming to leverage the various functions of lipids in human bodies, for example, in blood coagulation or as blood fats, to better interpret and predict a host of diseases.

29 Apr 2020

Scientists find gene signature linked to worst prognosis in rare uterine cancer

Women who don't survive a rare and aggressive uterine cancer called uterine serous carcinoma, have high expression of a group of 73 genes, a score scientists say can help identify these women and improve their outcome.

22 Apr 2020

UMSOM researchers uncover mechanism to explain role of genetic mutations in kidney disease

Researchers from the Center for Precision Disease Modeling at the University of Maryland School of Medicine have uncovered a mechanism that appears to explain how certain genetic mutations give rise to a rare genetic kidney disorder called nephrotic syndrome.

6 Apr 2020