Inflammation News and Research

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Study Offers New Insights Into Neuroendocrine Transdifferentiation in Breast and Prostate Cancer Biology

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "The senescence-associated secretory phenotype induces neuroendocrine transdifferentiation."

15 May 2023

Understanding How Cell-to-Cell Communication Networks Drive Pancreatic Cancer Development

Discussions of cancer often stress the genetic mutations that drive disease by altering the normal function of cellular proteins.

12 May 2023

Scientists Engineer the First CRISPR-Based Drug Candidate to Directly Target E. Coli

Many people have experienced infections from E. coli, which are primarily seen as inconvenient and unpleasant.

10 May 2023

Understanding How Interleukin-6 Contributes to Suppress Allergic Asthma and Atopy

The immune system has a biological telecommunications system -; small proteins known as interleukins that send signals among the leukocyte white blood cells to control their defense against infections or nascent cancer.

8 May 2023

Discovering Novel Senolytic Compounds with the Power of Artificial Intelligence

A new publication in the May issue of Nature Aging by researchers from Integrated Biosciences, a biotechnology company combining synthetic biology and machine learning to target aging, demonstrates the power of artificial intelligence (AI) to discover novel senolytic compounds, a class of small molecules under intense study for their ability to suppress age-related processes such as fibrosis, inflammation and cancer.

8 May 2023

New Insights on Cases of Post-Vaccine Heart Inflammation

Public health experts discovered an increase in cases of myocarditis, an inflammation of heart muscle, after the introduction of the new COVID-19 vaccinations two years ago, particularly in young males who had received mRNA vaccines.

8 May 2023

Inhibiting a Tiny RNA Could Help Improve Immune, Bone, and Muscle Health With Age

Inhibiting a tiny RNA whose levels significantly increase with age, along with problems like weaker bones and sagging muscles, may be a way to keep our bodies more youthful and healthy, scientists say.

3 May 2023

New Bio-Inspired Molecules can Enhance Bone Regeneration in Mice

People's ability to regenerate bones declines with age and is further decreased by diseases such as osteoporosis.

2 May 2023

The Pivotal Role of Combinatorial CRISPR Gene Editing in the Elimination of HIV-1 Infection

Recent research from Temple University’s Lewis Katz School of Medicine and the University of Nebraska Medical Center demonstrates that gene-editing therapy aimed at two targets - HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that aids the virus getting into cells—can effectively eliminate HIV infection.

2 May 2023

Genetic Variants of TNFAIP3 May Protect the Kidneys from Damage

A breakthrough in gene variants of an inflammation “brake” brings researchers one step closer to developing personalized treatments for those at risk of kidney disease and kidney failure.

26 Apr 2023

Genetic Variant Linked to Increased Risk of Developing Perianal Crohn's Disease

Cedars-Sinai investigators have identified a genetic variant that increases people's risk of developing perianal Crohn's disease, the most debilitating manifestation of Crohn's disease.

24 Apr 2023

The Function of ANKLE1 in the Prevention of DNA Damage and Autoimmunity

The University of Hong Kong (HKU) School of Biological Sciences research team led by Dr. Gary Ying Wai Chan has uncovered the function of a unique enzyme called ANKLE1.

19 Apr 2023

New Type of Drug Could Offer a Solution to Tackle Multidrug-Resistant Bacteria

A new type of drug could provide a way to treat multidrug-resistant bacteria, according to a study published in Nature Communications.

19 Apr 2023

Small Vesicles Originating From Intestinal Bacteria Have an Adverse Effect on the Liver

Researchers from Niigata University and Kyoto Prefectural University have revealed that small vesicles, around 100 nm in size, released by intestinal bacteria induce immune activation and progression of liver cirrhosis, as well as reduction of serum albumin level, subsequently leading to edema and ascites.

19 Apr 2023

Study Provides Increased Understanding of How Tick-Borne Encephalitis Virus Behaves in the Brain

The dreaded tick-borne encephalitis (TBE) virus infects different types of brain cells in different parts of the brain, depending on whether the affected person's immune system is activated or not.

18 Apr 2023

Inhibition of p21 may be a Promising Strategy for Limiting Age-Related Inflammatory Disorders

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 7, entitled, "p21 facilitates chronic lung inflammation via epithelial and endothelial cells."

18 Apr 2023

Study Provides Insight into the Formation of Protective Memory T Cells Against Salmonella

Salmonella infections cause about a million deaths a year worldwide, and there is an urgent need for better vaccines for both typhoid fever and non-typhoidal Salmonella disease.

18 Apr 2023

New Peptide Blocks a Hyperactive Brain Enzyme Involved in Neurodegeneration

MIT neuroscientists have found a way to reverse neurodegeneration and other symptoms of Alzheimer's disease by interfering with an enzyme that is typically overactive in the brains of Alzheimer's patients.

17 Apr 2023

Deletion of Specific Protein Creates a Hostile Environment for Aggressive Breast Tumors

Scientists at VCU Massey Cancer Center discovered that the deletion of a specific protein creates a hostile environment for tumor cells and significantly subdues breast cancer growth and spread.

13 Apr 2023

Glycine-Based Tripeptide Treats Severe Form of Fatty Liver Disease in Non-Human Primates

A recently developed amino acid compound successfully treats nonalcoholic fatty liver disease in non-human primates -; bringing scientists one step closer to the first human treatment for the condition that is rapidly increasing around the world, a study suggests.

11 Apr 2023

Inflammation News and Research

Study Offers New Insights Into Neuroendocrine Transdifferentiation in Breast and Prostate Cancer Biology

Understanding How Cell-to-Cell Communication Networks Drive Pancreatic Cancer Development

Scientists Engineer the First CRISPR-Based Drug Candidate to Directly Target E. Coli

Understanding How Interleukin-6 Contributes to Suppress Allergic Asthma and Atopy

Discovering Novel Senolytic Compounds with the Power of Artificial Intelligence

New Insights on Cases of Post-Vaccine Heart Inflammation

Inhibiting a Tiny RNA Could Help Improve Immune, Bone, and Muscle Health With Age

New Bio-Inspired Molecules can Enhance Bone Regeneration in Mice

The Pivotal Role of Combinatorial CRISPR Gene Editing in the Elimination of HIV-1 Infection

Genetic Variants of TNFAIP3 May Protect the Kidneys from Damage

Genetic Variant Linked to Increased Risk of Developing Perianal Crohn's Disease

The Function of ANKLE1 in the Prevention of DNA Damage and Autoimmunity

New Type of Drug Could Offer a Solution to Tackle Multidrug-Resistant Bacteria

Small Vesicles Originating From Intestinal Bacteria Have an Adverse Effect on the Liver

Study Provides Increased Understanding of How Tick-Borne Encephalitis Virus Behaves in the Brain

Inhibition of p21 may be a Promising Strategy for Limiting Age-Related Inflammatory Disorders

Study Provides Insight into the Formation of Protective Memory T Cells Against Salmonella

New Peptide Blocks a Hyperactive Brain Enzyme Involved in Neurodegeneration

Deletion of Specific Protein Creates a Hostile Environment for Aggressive Breast Tumors

Glycine-Based Tripeptide Treats Severe Form of Fatty Liver Disease in Non-Human Primates

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