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Developing Regenerative Therapies to Treat Neurological Conditions

The primary cells that make up our brain and spinal cord, called neurons, are among the slowest to heal after injury, and many neurons never fully recover. Although research into neural regeneration has advanced, it is still unclear why certain neurons recover while others do not.

17 Oct 2023

Breakthrough Research Discovers How the Body Controls Itch

It can be a relief to scratch the occasional itch, but when itch gets out of control, it can become a serious health problem. How does the body know when to stop?

16 Oct 2023

Fruit Fly Model Provides Insights into Pathogenesis of New Genetic Disorder

Research conducted in the laboratory of Dr Hugo J. Bellen, a Distinguished Service Professor at Baylor College of Medicine and a principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, has identified a novel disorder linked to gain-of-function variants in the DOT1L gene.

16 Oct 2023

New Atlases Reveal Unprecedented Detail of the Human Brain

In two concurrent projects, scientists at the Karolinska Institutet have played a significant role in producing the most extensive atlases of human brain cells to date.

13 Oct 2023

Increased Pain Sensitivity and Neanderthal Gene Variants

According to a recent study co-led by UCL researchers, those who contain three gene variations acquired from Neanderthals are more susceptible to specific types of pain.

11 Oct 2023

Study Links Autism Gene to Broad Spectrum of Molecular and Cellular Defects

Researchers have used CRISPR gene editing, stem cells and human neurons to study the impact of a gene that is commonly mutated in autism.

6 Oct 2023

Scientists Gain Insights into Biophysical Properties of Neurons with New Workflow

Biophysically detailed neuronal models provide a unique window into the workings of individual neurons.

5 Oct 2023

New Synthetic Biology Approach Offers Promise for Treating Neurodegenerative Diseases

Researchers at the University of Cologne's CECAD Cluster of Excellence for Aging Research and the CEPLAS Cluster of Excellence for Plant Sciences have found a promising synthetic plant biology approach for the development of a therapy to treat human neurodegenerative diseases, especially Huntington's disease.

3 Oct 2023

Fruit Flies Show How Brain Reward-Based Decisions Work

Fitzgerald’s brother-in-law, like many L.P. record collectors, has a go-to store where he routinely finds the greatest vinyl for his collection.

25 Sep 2023

Bioprinted Neural Networks Mimic Brain Circuitsdani

Researchers from Monash University’s Engineering Department have achieved a significant breakthrough by using “bioinks” that include living nerve cells (neurons) to 3D print nerve networks.

22 Sep 2023

How Scientists are Using iPSCs to Develop New Therapies

In 1998, scientists reported being able to derive cells from human embryos that could develop into almost any cell in the body. In 2007, the field took a huge leap when scientists discovered they could reprogram human adult skin cells to act like these embryonic stem cells.

20 Sep 2023

Brain's Choreography of Movement Unveiled in Zebrafish Study

The zebrafish brain, though simpler than its human counterpart, is a complex network of neurons that engage in a ceaseless dance of electrical activity.

11 Sep 2023

Largest Genetic Study Discovers Specific DNA Changes That Increase Risk of Epilepsy

The largest genetic study of its kind, coordinated by the International League Against Epilepsy, including scientists from FutureNeuro at RCSI University of Medicine and Health Sciences, has discovered specific changes in our DNA that increase the risk of developing epilepsy.

5 Sep 2023

The Evolution of Epilepsy and Potential Cure: A New Study

Specific alterations in human DNA have been shown to raise the likelihood of getting epilepsy, according to the biggest genetic study of its type, which was managed by the International League Against Epilepsy and involved researchers from FutureNeuro at RCSI University of Medicine and Health Sciences.

1 Sep 2023

The Pathogenic Mechanism Underpinning MEPAN Syndrome

New research published in Nature Metabolism discovered the pathogenic mechanism driving mitochondrial enoyl reductase protein-associated neurodegeneration (MEPAN) syndrome, a rare pediatric neurodegenerative disease.

1 Sep 2023

Bats' Navigation Brain Cells Also Encode Social Information

The same neurons that help bats navigate through space may also help them navigate collective social environments, finds a new study published today in the journal Nature.

31 Aug 2023

Genetic Risk of Depression Linked to Increased Risk of Other Psychiatric Disorders

Recent research reveals that people who are hospitalized for depression are at an increased risk of developing conditions like substance abuse, bipolar disorder, schizophrenia, and anxiety, depending on their genetic predisposition to the individual disorder.

30 Aug 2023

The Art of Neuroscience: Synaptic Transmission and Plasticity in Isolated Neurons

Studying the complex interactions between synaptic nerve endings as well as their development has now become much easier.

30 Aug 2023

T Cells Infiltrate Brain and Worsen Alzheimer's Pathology, Study Finds

Cognitive decline associated with Alzheimer's disease (AD) develops when neurons begin to die, which can be caused by inappropriate immune responses and excessive inflammation in the brain triggered by amyloid beta deposits and tau tangles, two hallmarks of the disease.

28 Aug 2023