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New highly sensitive RNA detection method advances in situ transcriptomics

Human cells typically transcribe half of their roughly 20,000 genes into RNA molecules at any given time. Just like with proteins, the function of those RNA species not only relies on their abundance but also their precise localization within the 3D space of each cell.

18 Mar 2021

Scientists find a better way to identify cells and understand disease mechanisms

In researching the causes and potential treatments for degenerative conditions such as Alzheimer's or Parkinson's disease, neuroscientists frequently struggle to accurately identify cells needed to understand brain activity that gives rise to behavior changes such as declining memory or impaired balance and tremors.

18 Mar 2021

Researchers identify address codes in odorant receptor proteins for the first time

A team of scientists led by Dietmar Krautwurst from the Leibniz Institute for Food Systems Biology at the Technical University of Munich has now identified address codes in odorant receptor proteins for the first time.

18 Mar 2021

Scientists provide a complete phenotypic landscape of SCN2A-related disorders

Researchers from Children's Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have compiled a complete genetic and clinical analysis of more than 400 individuals with SCN2A-related disorder, which has been linked to a variety of neurodevelopmental disorders, including epilepsy and autism.

18 Mar 2021

$1 million NSF grant effort to explore a natural process that saps plants' productivity

Plants were evolving for hundreds of millions of years before humans started cultivating them for food. So when the first farmers showed up some 12,000 years ago, plants had already picked up some inefficiencies -- that is, adaptations that helped the plants survive but also limited their productivity as crops.

17 Mar 2021