Electron Microscopy News and Research

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Study unravels new aspects of prions causing untreatable neurodegenerative conditions

A new study achieved the highest-ever resolution imaging of an infectious prion, offering atomic-level data of how these abnormal proteins assemble.

25 Aug 2021

New system solves 3D structures of RNA-only molecules with unprecedented speed and accuracy

The single-stranded genetic material RNA is best known for guiding the assembly of proteins in our cells and carrying the genetic code for viruses like SARS-CoV-2 and HIV.

16 Aug 2021

Scientists develop new tool to identify neuronal proteins in animal models

Scientists, for the first time, developed a successful method for pinpointing proteins within different kinds of neurons in the brain of a living animal.

16 Aug 2021

Study on protein complex could help support cancer prevention efforts, drug development

Researchers have used sophisticated imaging technology to offer unmatched insights into the BRCA1-BARD1 protein complex.

29 Jul 2021

Researchers employ 3D holographic microscopy to visualize bioplastic in living cells

Scientists from KAIST inspected the accumulation of bioplastic granules in living bacterial cells with the help of 3D holographic microscopy.

29 Jul 2021

Study identifies the role of lysosomes in the spread of Parkinson’s disease

In the past few decades, neurodegenerative diseases have turned into one of the top 10 worldwide causes of death.

26 Jul 2021

Cell couriers offer clue to how cancers metastasize into secondary tumors

A protein involved in making cells move offers a clue to how certain types of cancer metastasize and develop into secondary tumors, according to new research from the University of Warwick.

From The University of Warwick 22 Jul 2021

Research substantiates nanoparticles as promising platforms for cell nano-sensors

Researchers published an article that represents the transmission electron microscopy (TEM) and flow cytometry study of A-549 (human lung carcinoma) cellular uptake of Pr3+:LaF3 nanoparticles.

21 Jul 2021

Nanobody mapping using NMR proves a promising alternative for therapeutic use

Researchers used NMR techniques to determine the structure of a nanobody, facilitating a better understanding of how the protein fights against diseases.

6 Jul 2021

Mutations on SARS-CoV-2 spike proteins create antibody-resistant variants

Researchers have identified how mutations on the SARS-CoV-2 spike protein separately create variants that are potentially resistant to antibodies.

1 Jul 2021

Novel technique greatly increases the resolution of atomic force microscopy

Scientists at Weill Cornell Medicine have developed a computational technique that greatly increases the resolution of atomic force microscopy, a specialized type of microscope that "feels" the atoms at a surface.

17 Jun 2021

Study decodes the activation mechanism of immune cells

Chemokines are small proteins that adhere to these chemokine receptors and regulate the behavior and movement of white blood cells.

17 Jun 2021

Researchers identify new therapeutic targets for flaviviruses

In a recent study, Australian scientists used an original approach to resolve the 3D structure of flaviviruses with an unprecedented level of detail, identifying small molecules known as 'pocket factors' as new therapeutic targets.

2 Jun 2021

24 Hours of Life Science Online Conference

On June 2, 2021, JEOL will focus on advances in life science research using electron microscopy in its “24 Hours of Life Science” conference.

From JEOL USA, Inc. 21 May 2021

Natural molecule can effectively block the binding of human antibodies to SARS-CoV-2

Researchers have found that a natural molecule can effectively block the binding of a subset of human antibodies to SARS-CoV-2. The discovery may help explain why some COVID-19 patients can become severely ill despite having high levels of antibodies against the virus.

23 Apr 2021

Study reveals how some antibodies can effectively disable ebolaviruses

Some survivors of ebolavirus outbreaks make antibodies that can broadly neutralize these viruses--and now, scientists at Scripps Research have illuminated how these antibodies can disable the viruses so effectively. The insights may be helpful for developing effective therapies.

16 Apr 2021

Novel method to activate and visualize protein channels that keep bacteria alive

Almost all bacteria rely on the same emergency valves--protein channels that pop open under pressure, releasing a deluge of cell contents.

15 Apr 2021

Study discovers how some proteins ensure repair of errors introduced during DNA replication

Researchers have discovered how specific proteins ensure the rectification of errors introduced into the DNA when it replicates.

7 Apr 2021

Supercomputer simulations help uncover the mechanism for HIV replication

Viruses lurk in the grey area between the living and the nonliving, according to scientists. Like living things, they replicate but they don't do it on their own. The HIV-1 virus, like all viruses, needs to hijack a host cell through infection in order to make copies of itself.

1 Apr 2021

Study reveals how lipids and water molecules control 5-hydroxytryptamine receptors

Serotonin, or 5-hydroxytryptamine (5-HT), is a kind of neurotransmitter. 5-HT can regulate multifaceted physiological functions such as mood, cognition, learning, memory, and emotions through 5-HT receptors.

26 Mar 2021