Electron Microscopy News and Research

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Cryo-EM reveals the structure of fermentation enzyme phosphoketolase

Pharmaceuticals, plastics, and other industries use enzymes to help synthesize molecular feedstocks.

19 Apr 2022

Max Planck researchers reveal the structure of kinetochore corona

During cell division in a mother cell, the 23 chromosomes that carry the human genome must be first copied and later delivered to two newly forming daughter cells.

From The Max Planck Institute 11 Apr 2022

Scientists gain fascinating insights into the dynamic ultrastructure of the heart

What happens below the cellular level when the heart contracts and relaxes has long been unexplored. Thanks to new ultra-high-resolution electron microscopy techniques, scientists can now watch the heart beating – almost at a molecular level.

11 Apr 2022

Cryo-EM imaging of STING protein reveals a new binding source for immune attacks

In new research, UT Southwestern scientists report that imaging a key immunity protein known as STING at near-atomic resolution reveals a previously undiscovered binding location that appears to be crucial for launching immunological attacks.

11 Apr 2022

Rockefeller scientists reveal how a narrow-spectrum antibiotic selectively targets C. diff

Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome.

7 Apr 2022

Researchers discover a unique technique to fight hospital-borne disease

A study team developed an early-stage therapy that sabotages the pump and restores antibiotic efficiency by disclosing the structure of a protein needed by bacteria to pump out antibiotics.

From New York University (NYU) 4 Apr 2022

Research reveals how a building block protein assembles to form poxvirus scaffold

Researchers at the Okinawa Institute of Science and Technology Graduate University have revealed how poxviruses build their scaffold - a temporary protein coat that forms and disappears as the virus matures.

1 Apr 2022

Plant biologists determine molecular ‘blueprint’, showing how plants observe light

For survival, plants depend on their ability to detect light. Plants, unlike animals, do not have photoreceptors in their eyes to receive and transmit messages from visual inputs.

1 Apr 2022

Scientists reveal how 9-1-1 clamp attaches to DNA damage site for initiating effective repair

DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.

22 Mar 2022

Researchers use GP2 and UMOD to prevent urinary tract infection

A team led by Karolinska Institute used AI and structural biology to learn more about two similar proteins that protect against bacterial infection in the urinary tract.

16 Mar 2022

Cryo-EM reveals how a bacterial protein senses and rescues stalled ribosomes

As a molecular machine found in the cells of all organisms, the ribosome is responsible for making new proteins.

11 Mar 2022

Scientists observe first high-resolution 3D image of muscle protein nebulin

Skeletal and heart muscle owe their function as stable biological machines to the outstanding accuracy with which their sarcomeres are assembled.

22 Feb 2022

Study develops AI-based method to help analyze protein complexes

A new technique for analyzing proteins has been developed by researchers at Martin Luther University Halle-Wittenberg (MLU) and the European Molecular Biology Laboratory in Hamburg.

21 Feb 2022

3D structure of protein channel helps shed light on sensitive touch response of Venus fly traps

Scientists at Scripps Research have revealed the three-dimensional structure of Flycatcher1, an aptly named protein channel that may enable Venus fly trap plants to snap shut in response to prey.

18 Feb 2022

Cryo-electron microscopy reveals structures of a muscle-type nicotinic acetylcholine receptor

New research co-led by a University of Ottawa Faculty of Medicine professor is shedding light on some of the mysterious dynamics that define the interplay between nerves and muscle.

17 Feb 2022

Novel function of anti-HIV-1 antibodies discovered using robust microscopy techniques

Using cutting-edge imaging methods on in vitro virus cells, researchers from the Institut Pasteur, CNRS, VRI, and Université de Paris found a role of anti-HIV-1 antibodies.

From Institut Pasteur 14 Feb 2022

First 3D structure of regulator protein elucidated in almost atomic resolution

Proteins are indispensable components in living organisms. They are not only "building material" for the body – they also make molecular communication between cells possible, they are needed for nerve impulses to occur, and they control chemical reactions.

3 Feb 2022

Electron Microscopy News and Research

Cryo-EM reveals the structure of fermentation enzyme phosphoketolase

Max Planck researchers reveal the structure of kinetochore corona

Scientists gain fascinating insights into the dynamic ultrastructure of the heart

Cryo-EM imaging of STING protein reveals a new binding source for immune attacks

Rockefeller scientists reveal how a narrow-spectrum antibiotic selectively targets C. diff

Researchers discover a unique technique to fight hospital-borne disease

Research reveals how a building block protein assembles to form poxvirus scaffold

Plant biologists determine molecular ‘blueprint’, showing how plants observe light

Scientists reveal how 9-1-1 clamp attaches to DNA damage site for initiating effective repair

Researchers use GP2 and UMOD to prevent urinary tract infection

Cryo-EM reveals how a bacterial protein senses and rescues stalled ribosomes

Scientists observe first high-resolution 3D image of muscle protein nebulin

Study develops AI-based method to help analyze protein complexes

3D structure of protein channel helps shed light on sensitive touch response of Venus fly traps

Cryo-electron microscopy reveals structures of a muscle-type nicotinic acetylcholine receptor

Novel function of anti-HIV-1 antibodies discovered using robust microscopy techniques

First 3D structure of regulator protein elucidated in almost atomic resolution

Scientists visualize protein machinery of respiration with unparalleled precision

Experts unravel a new form of communication between brain cells

Structural proteomics approaches show promise for treating neurodegenerative diseases

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