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Olfactory receptor gene may drive breast cancer metastasis to the brain

An olfactory receptor gene that aids in the sense of smell may also play a role in the metastasis of breast cancer to the brain, bones and lung, researchers from Massachusetts General Hospital have found.

4 Jan 2022

DNA analyses reveals insights into ancestry, social organization of ancient people in the Nile Valley

The first genome-wide ancient human DNA data from Sudan reveals new insights into the ancestry and social organization of people who lived more than 1,000 years ago in the Nile Valley, an important genetic and cultural crossroads.

20 Dec 2021

Researchers use CRISPR-Cas9 to successfully target brown fat

Fat is an essential component of life, however too much fat leads to numerous health issues. Investigating the role played by fat or adipose tissue is significant to get a better understanding of obesity and other problems.

17 Dec 2021

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Mount Sinai researchers have solved a major mystery in cancer research: How cancer cells remain dormant for years after they leave a tumor and travel to other parts of the body, before awakening to create metastatic cancer.

14 Dec 2021

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

New classification method divides breast cancers into 12 distinct biological groups

Researchers at UNC Lineberger Comprehensive Cancer Center have taken a major step forward in melding two key methods for studying breast cancer: one by genetic analysis and the second by looking at the architecture of cells, or their pathology.

9 Dec 2021

Immune cells utilize the body’s fat stores to combat infection, says study

A recent study carried out by the University of East Anglia and Quadram Institute shows how immune cells utilize the body’s fat stores to combat infection.

9 Dec 2021

People previously infected by Chikungunya virus may develop partial immunity to Mayaro virus

A study conducted at the University of São Paulo (USP) in Brazil suggests people previously infected by Chikungunya virus may develop partial immunity to Mayaro virus.

6 Dec 2021

Immune cells in the brain mediate the link between gut microbiome and amyloid beta deposits

New research from the University of Chicago points to microglia, key immune cells in the brain, as a key mediator in the relationship between the gut microbiome and b-amyloid deposits in male mice in a model of Alzheimer's disease.

3 Dec 2021

Anti-idiotype antibodies may explain the long-term effects of COVID-19

With around 256 million cases and more than 5 million deaths worldwide, the COVID-19 pandemic has challenged scientists and those in the medical field. Researchers are working to find effective vaccines and therapies, as well as understand the long-term effects of the infection.

From The University of California, Davis 26 Nov 2021

New details about Shigella's translocon may help develop effective strategy to block infection

Shigella, a bacterial pathogen that causes dysentery and is the leading cause of childhood diarrheal diseases, inserts a pore called a translocon into an infected person's intestinal cells and then injects bacterial proteins into the cells.

24 Nov 2021

Research demonstrates how diet affects immunity through the gut microbiome

The cliché "you are what you eat" has been used for hundreds of years to illustrate the link between diet and health. Now, an international team of researchers has found the molecular proof of this concept, demonstrating how diet ultimately affects immunity through the gut microbiome.

From Harvard Medical School 17 Nov 2021

Macrophages found in cardiac tissue protect the failing heart, says study

The Centers for Disease Control and Prevention states that heart failure impacts over six million Americans and is the major reason for death.

17 Nov 2021

Study discusses outcomes of disclosing actionable genetic results to research participants

Over 120,000 patients have enrolled in the Mass General Brigham Biobank, offering access to crucial information related to their health history.

10 Nov 2021

Study finds several common genetic loci associated with dilated cardiomyopathy in U.S. veterans

A genome-wide association study has identified several common genetic loci (genetic locations) associated with dilated cardiomyopathy in U.S. veterans of European and African ancestry, according to preliminary research to be presented at the American Heart Association's Scientific Sessions 2021.

9 Nov 2021

Medical School News and Research

Olfactory receptor gene may drive breast cancer metastasis to the brain

DNA analyses reveals insights into ancestry, social organization of ancient people in the Nile Valley

Researchers use CRISPR-Cas9 to successfully target brown fat

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

New classification method divides breast cancers into 12 distinct biological groups

Immune cells utilize the body’s fat stores to combat infection, says study

People previously infected by Chikungunya virus may develop partial immunity to Mayaro virus

Immune cells in the brain mediate the link between gut microbiome and amyloid beta deposits

Anti-idiotype antibodies may explain the long-term effects of COVID-19

New details about Shigella's translocon may help develop effective strategy to block infection

Research demonstrates how diet affects immunity through the gut microbiome

Macrophages found in cardiac tissue protect the failing heart, says study

Study discusses outcomes of disclosing actionable genetic results to research participants

Study finds several common genetic loci associated with dilated cardiomyopathy in U.S. veterans

Experts identify novel mechanisms involved in macrophage polarization

Torquetenovirus in people infected by SARS-CoV-2 can be used as a marker of disease severity

Simultaneously Measuring 7,000 Proteins: Groundbreaking Proteomics from SomaLogic

Research reveals pathways controlling osteocyte development

Study reveals a link between prenatal PFAS exposure and late-onset preeclampsia

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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