Pharmacology News and Research

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Pharmacology is the study of how chemical substances interact with living systems. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, interactions, toxicology, therapy, and medical applications and antipathogenic capabilities.

Human stem cell models reveal neurodegeneration in glaucoma

Glaucoma, a serious eye condition responsible for causing vision loss, affects over three million Americans.

12 Jun 2020

'Fat burning' molecule holds promise for future treatment and prevention of obesity

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population.

9 Jun 2020

New technology to rapidly create antibody-drug conjugates

A USC School of Pharmacy-led team has engineered a new, faster way to make drugs that precisely target malignant cells - while leaving healthy tissue undamaged - that could lead the way to better treatments for numerous types of cancer.

5 Jun 2020

Making opioids safer and more effective

Dr. John Streicher speaks to AZoLifeSciences about his research on improving opioid drugs to make them safer and more effective.

From University of Arizona 28 May 2020

Genetic discoveries raise the promise of developing new treatments for schizophrenia

In recent years, genome-wide association studies have identified many different genetic variants associated with schizophrenia.

22 May 2020

Chemicals Often Found In Consumer Products Could Lead To Obesity And Fatty Liver Diseases

Chemical compounds found in many consumer products could be major contributors to the onset of lipid-related diseases, such as obesity according to a study.

22 May 2020

Researchers develop new AI model to bridge biology and chemistry

Insilico Medicine announces the publication of a new research paper titled "Molecular Generation for Desired Transcriptome Changes With Adversarial Autoencoders" in Frontiers in Pharmacology.

20 May 2020

A New Imaging Approach To See Multiple Proteins Simultaneously

Degenerative diseases such as Alzheimer's often involve complex interactions between multiple proteins and other biomolecules.

19 May 2020

A New Tool To Map The Flow Of Info Within Living Cells

How do cells move? Why do they move? Why do some cancer cells move slowly while others move quickly, causing cancerous tumors to become more difficult to treat?

19 May 2020

The microbiome regulates our immune system's fitness

Working alongside colleagues in Mainz, Bern, Hannover and Bonn, researchers from Charité - Universitätsmedizin Berlin, the Berlin Institute of Health and the German Rheumatism Research Center Berlin were able to show how the microbiome helps to render the immune system capable of responding to pathogens.

13 May 2020

Scientists elucidate precise shape of a key player in human metabolism

A USC-led international team of scientists has found the precise shape of a key player in human metabolism, which could lead the way to better treatments for obesity and other metabolic disease.

24 Apr 2020

Orujo Olive Oil Reduces Obesity

Researchers have confirmed that Orujo olive oil produces a significant reduction in obesity and inflammatory complications in obese mice.

24 Apr 2020

Discovery marks a critical step toward developing new anti-cancer drugs

A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer.

21 Apr 2020

Researchers use genome-wide CRISPR technology to identify leukemia's weakness

A team of researchers at University of California San Diego School of Medicine and Moores Cancer Center used CRISPR technology to identify key regulators of aggressive chronic myeloid leukemia, a type of cancer that remains difficult to treat and is marked by frequent relapse.

From UC San Diego 21 Apr 2020

Chemical tools can regulate lipid concentration in living cells

Lipids have several crucial functions in the human body: They serve as messengers, which mediate the growth of cells and regulate the release of hormones.

20 Apr 2020

How human cells recognize undesirable guests

Until now, the immune sensor TLR8 has remained in the shadows of science. A research team led by the University of Bonn has now discovered how this sensor plays an important role in defending human cells against intruders.

15 Apr 2020

Role of VRAC ion channel in fight against virus infections

VRAC/LRRC8 chloride channels play a crucial role in the transport of neurotransmitters, amino acids, and cytostatics.

14 Apr 2020

Breakthrough In Unlocking Genetic Potential Of Ocean Microbes

Researchers have made a major breakthrough in developing gene-editing tools to improve our understanding of ocean microbes.

10 Apr 2020

Gene-editing tools developed to study ocean microbes

Researchers have achieved significant progress in the development of gene-editing tools that could help gain better insights into one of the most crucial ocean microbes on the planet.

8 Apr 2020

Researchers develop 3D cultured cells that mimic liver fibrosis

Headed by researchers from Japan-based Tokyo University of Agriculture and Technology (TUAT), a group of scientists has effectively established three-dimensional (3D) cultured tissue that imitates liver fibrosis, which is a major trait of non-alcoholic steatohepatitis (NASH).

2 Apr 2020