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Anti-hypertension drug prolongs lifespan in C. elegans, research shows

A stress response of mitochondria, the part of our cells that produce energy to power bodily functions, is important to a longer life.

21 Dec 2020

Study demonstrates drug repurposing can be used to treat genetic diseases

A new study by researchers at the University of Illinois Chicago describes a potential technique of using drug repurposing for the treatment of genetic diseases.

18 Dec 2020

New method boosts the extraction of vegetable oil from plants

Vegetable oils provide significant health benefits, like reducing the risk of cardiovascular disease and lowering cholesterol levels.

18 Dec 2020

New study targets small proteins in Salmonella to combat the pathogen

Salmonella is a type of bacteria that causes food poisoning upon infection, with acute diarrhea.

17 Dec 2020

TGen identifies genetic target that could help explain the variation in COVID-19 effects

The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become.

17 Dec 2020

Study may lead to new treatments for certain types of disease

Researchers at the Francis Crick Institute have found a new way to prevent some tumours from repairing their own DNA, a function that is essential for cancer cell survival. This discovery could lead to much needed new treatments for certain types of the disease.

17 Dec 2020

Study: DOT1L enzyme is essential for humoral immune responses

Communication, serendipity and an enzyme called DOT1L have all combined to produce some exciting findings into the immune system's B cells and T cells by two groups of Monash Biomedicine Discovery Institute (BDI) scientists.

17 Dec 2020

Researchers discover genetic variants of host proteins involved in SARS-CoV-2 infection

Like all viruses, the novel coronavirus is dependent on help from the human host cell. Proteins are the functional units of the cell and enable the virus to enter the host cell or help the virus to replicate.

17 Dec 2020

Mouse stem cells converted into oocyte-like cells by just eight genes

Researchers have demonstrated that activating eight genes is enough to induce the stem cells of mice to transform into oocyte-like cells that can be fertilized.

17 Dec 2020

Gene expression database sheds light on pneumococcal infection

Researchers at the University of Maryland School of Medicine published one of the most comprehensive analyses of how genes get expressed during infection (known as a transcriptome).

16 Dec 2020

Scientists invent new RNA drug-discovery tool for undruggable diseases

Imagine trying to throw a bullseye when the dartboard lies buried within a crumpled box. That's the challenge faced by scientists working to make new medicines for some "undruggable" diseases, including a type of metastatic breast cancer.

16 Dec 2020

Researchers develop genetic markers to monitor herring populations and avoid overfishing

An international team of Swedish, Norwegian, Danish and Irish scientists has used whole-genome sequencing to characterize 53 herring populations from the Atlantic Ocean and the Baltic Sea.

16 Dec 2020

New genomic tool can accurately assess the risk of breast cancer

Breast cancer is the most commonly diagnosed disease in women and is the main cause of cancer-related mortalities in this group of population.

15 Dec 2020

Study sheds new light on a genetic developmental disorder

The rare hereditary developmental disorder, called Meier-Gorlin syndrome, or MGS for short, causes dwarfism, missing patella, a small brain, small ears, and other skeletal abnormalities. This condition leads to stillbirths and miscarriages in severe cases.

15 Dec 2020

New study dispels concerns that human stem cells contain cancer-causing mutations

Pioneering new research has made a pivotal breakthrough that dispel concerns that human stem cells could contain cancer-causing mutations.

From University of Exeter 15 Dec 2020

Molecular markers in the blood can predict severe COVID-19 outcomes

Molecular markers in the blood shown to be predictive of severe COVID-19 outcomes resulting from SARS-CoV-2 coronavirus infection have been identified in a study by a Chinese research team.

15 Dec 2020

Researchers provide a list of genes implicated in congenital heart disease

Over two million babies, children, and adults in the United States are living with congenital heart disease--a range of birth defects affecting the heart's structure or function.

15 Dec 2020

New combination therapy could be effective in treating aggressive cancers with common mutations

Scientists have long known that therapies that target the cancer-driving MAPK pathway are only effective in a handful of cancers with specific mutations in a cancer gene called BRAF, and these cancers that initially respond to the therapy often end up developing resistance to the treatment, resulting in relapse for many patients.

15 Dec 2020

Scientists identify biosynthetic genes involved in the production of usnic acid in lichens

Scientists from the Faculty of Pharmacy at the Complutense University of Madrid have headed an international study that has successfully detected a sequence of biosynthetic genes that play a key role in the synthesis of usnic acid in lichen—a kind of compound that exhibits antioxidant, antiviral, antibacterial, anticancer, and neuroprotective activity.

14 Dec 2020

Study elucidates genes responsible for Glioblastoma invasiveness

One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into the normal brain tissue.

14 Dec 2020