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Revolutionary CRISPR-based genome editing system treatment destroys cancer cells

Researchers at Tel Aviv University have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers.

11 Dec 2020

Scientists aim to treat and prevent disease by understanding exercise benefits

A top exercise researcher and colleagues at the University of Virginia School of Medicine have launched an ambitious effort to understand the whole-body benefits of exercise so that doctors can use that information to prevent and treat disease.

11 Dec 2020

New model helps assess the effect of epigenetic changes on gene expression

Researchers have developed a mathematical model to quantitatively assess the impacts of particular epigenetic changes on the transcription rates.

11 Dec 2020

Newly identified Cas9 nucleases can improve genome editing

Scientists have explained two new compact Cas9 nucleases that will possibly extend the Cas9 toolbox for genome editing.

11 Dec 2020

A genetic shortcut to help visualize proteins at work

A group at Gladstone Institutes and UC San Francisco (UCSF) has demonstrated that a large-scale and systematic genetic approach can indeed yield reliable and detailed information on the structure of protein complexes.

11 Dec 2020

Study shed light on how genes affect the risk for coronary artery disease

Researchers at the University of Virginia have shed light on how our genes affect our risk for coronary artery disease, the most common form of heart disease.

11 Dec 2020

Researchers identify new therapeutic target to treat type 1 diabetes

Scientists from the University of Utah School of Medicine have discovered a novel therapeutic target to treat type 1 diabetic patients.

10 Dec 2020

Tight arrangement between root endodermis and microbiome maintains mineral balance in plants

In a similar way to animal guts and the intestinal epithelium, plant roots are in charge of absorbing nutrients and water and of its subsequent transport to the vascular systems.

10 Dec 2020

Study sheds light on molecular underpinnings of long-term memory

On a late summer day in 1953, a young man who would soon be known as patient H.M. underwent experimental surgery.

From Harvard Medical School 10 Dec 2020

Neuropeptides produced by cockroaches could someday be targeted by new pesticides

Cockroaches are notorious for their abilities to survive and reproduce, much to humanity's chagrin. In addition to scurrying around at night, feeding on human and pet food, and generating an offensive odor, the pests can transmit pathogens and cause allergic reactions.

10 Dec 2020

Appendiceal cancer among young patients harbors a distinct biology, shows study

The first study to compare molecular landscapes of early-onset and late-onset appendiceal cancer has revealed distinct non-silent mutations in the tumors of younger patients, setting the stage for the development of potential therapeutic advances for this rare disease.

From Vanderbilt University 10 Dec 2020

Researchers develop new, simpler way to treat sewage

Researchers from the National University of Singapore (NUS) have developed a new way to treat sewage that is much simpler, cheaper and greener than existing methods.

From National University of Singapore (NUS) 10 Dec 2020

Repair proteins can help healthy cells to avoid damage during cancer therapy

A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.

10 Dec 2020

Researchers identify key molecular processes used by coronaviruses to survive

When a coronavirus--including SARS-CoV-2, which causes COVID-19--infects someone, it hijacks the person's cells, co-opting their molecular machinery for its own survival and spread.

9 Dec 2020

Research clarifies regulatory impacts of ubiquitin-proteasome system on DNA damage repair

An international research team has clarified the regulatory mechanism of the ubiquitin-proteasome system (*1) in recognizing and repairing DNA that has been damaged by ultraviolet (UV) light.

9 Dec 2020

Researchers discover genetic factors underlying diabetic retinopathy

In a quest to find the genetic factors that are fundamental to diabetic retinopathy, scientists from the University of Illinois Chicago (UIC) have also discovered a new method that can be employed as a template to investigate other types of diseases.

8 Dec 2020

Specific cellular pathways in the fetal gut may reactivate Crohn’s Disease

Researchers have successfully monitored the initial stages of gut development in a human fetus, in explicit detail.

8 Dec 2020

Sensitive testing system allows rapid and reliable detection of resistance in bacteria

Researchers from the University of Basel have developed a sensitive testing system that allows the rapid and reliable detection of resistance in bacteria.

8 Dec 2020