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Circular Extrachromosomal DNA Linked to Medulloblastoma Relapse and Death

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA-;loops of DNA found outside of regular chromosomes-;are twice as likely to relapse and three times as likely to die within five years of diagnosis.

15 Nov 2023

Cancer Stem Cells Induce Macrophage Senescence, Creating Conditions for Tumor Formation

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.

15 Nov 2023

Study Sheds Light on Factors Contributing to Low-Level Viremia in HIV Patients

Human immunodeficiency virus (HIV) works by entering specific immune cells and replicating inside them.

15 Nov 2023

Rare Genetic Variant Found to Protect Against Alzheimer's Disease

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

14 Nov 2023

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.

14 Nov 2023

Stanford Researchers Discover New Mechanism for Breast Cancer Invasion

The majority of breast cancers start in the lining of a breast milk duct and, if they remain there, are very treatable.

14 Nov 2023

Scientists Identify 4,749 Gene Clusters Linked to Cancer Prognosis

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

14 Nov 2023

Exploring How Climate Change Could Impact Our Brain Function in the Future

A new element of the catastrophic impacts of climate change is emerging – how global warming is impacting the human brain.

14 Nov 2023

New Computational Method Predicts the Stability of Pharmaceutical Crystalline Forms

Physical properties (stability, solubility, etc.), critical to the performance of pharmaceutical and functional materials, are known to strongly depend on the solid-state form and environmental factors, such as temperature and relative humidity.

13 Nov 2023

LJI Scientists Uncover New Superpower of MAIT Cells

Scientists at La Jolla Institute for Immunology (LJI) are investigating a talented type of T cell.

13 Nov 2023

Quantum Biology and AI Improve CRISPR Cas9 Efficiency in Microbes

Scientists at Oak Ridge National Laboratory used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

10 Nov 2023

New Synthetic Enzymes can Control Signaling Protein Vital to Embryonic Development

A University of Texas at Dallas bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone and blood in vertebrate embryos.

10 Nov 2023

Bacteria and Viruses Evolve New Strategies in Accelerated Arms Race

As conceived by Charles Darwin in the 1800s, evolution is a slow, gradual process during which species adaptations are inherited incrementally over generations.

10 Nov 2023

Large Study Finds 187 New Genetic Variants Linked to Prostate Cancer

A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk -; 451 in all -; through a whole-genome analysis that ranks as the largest and most diverse investigation into prostate cancer genetics yet.

10 Nov 2023

Dissecting the Mechanisms Behind Selective Genomic Editing

A new study is in progress to unravel a fascinating biological mystery of how certain animals can naturally eliminate more than half of their genetic information during embryonic development.

10 Nov 2023

Examining the Link Between Sleep Alteration and Aging in Jewel Wasps

Parents of newborns might sense a rapid aging effect during the early months of sleepless nights. Currently, researchers at the University of Leicester are exploring the intriguing possibility that the key to a long and healthy life lies in a restful night's sleep and human DNA.

10 Nov 2023

New Insights Into Tumor-Immune Interactions Could Lead to More Effective Therapies for Multiple Myeloma

A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.

10 Nov 2023

Novel Bacterial Protein can Prolong Cell Longevity by Acting Directly on Mitochondria

Researchers at the University of São Paulo (USP) in Brazil, partnering with colleagues in Australia, have identified a novel bacterial protein that can keep human cells healthy even when the cells have a heavy bacterial burden.

10 Nov 2023

Seventh Annual NSF-Funded Solicitation for Tissue Engineering Research Utilizing the ISS National Lab Now Open

For the seventh consecutive year, the U.S. National Science Foundation (NSF) is funding a solicitation seeking projects that utilize the International Space Station (ISS) National Laboratory to advance tissue engineering and mechanobiology research. Through this solicitation, NSF will provide up to $1.6 million in funding for multiple projects intending to leverage the orbiting laboratory.

10 Nov 2023

A Glimpse Into the World of Bacterial Metabolism Within Hosts

Researchers from Kiel University (CAU) and the Max Planck Institute for Marine Microbiology in Bremen are shedding light on the enigmatic world of bacteria that coexist or parasitize animal hosts.

9 Nov 2023

Research News and Research

Circular Extrachromosomal DNA Linked to Medulloblastoma Relapse and Death

Cancer Stem Cells Induce Macrophage Senescence, Creating Conditions for Tumor Formation

Study Sheds Light on Factors Contributing to Low-Level Viremia in HIV Patients

Rare Genetic Variant Found to Protect Against Alzheimer's Disease

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Stanford Researchers Discover New Mechanism for Breast Cancer Invasion

Scientists Identify 4,749 Gene Clusters Linked to Cancer Prognosis

Exploring How Climate Change Could Impact Our Brain Function in the Future

New Computational Method Predicts the Stability of Pharmaceutical Crystalline Forms

LJI Scientists Uncover New Superpower of MAIT Cells

Quantum Biology and AI Improve CRISPR Cas9 Efficiency in Microbes

New Synthetic Enzymes can Control Signaling Protein Vital to Embryonic Development

Bacteria and Viruses Evolve New Strategies in Accelerated Arms Race

Large Study Finds 187 New Genetic Variants Linked to Prostate Cancer

Dissecting the Mechanisms Behind Selective Genomic Editing

Examining the Link Between Sleep Alteration and Aging in Jewel Wasps

New Insights Into Tumor-Immune Interactions Could Lead to More Effective Therapies for Multiple Myeloma

Novel Bacterial Protein can Prolong Cell Longevity by Acting Directly on Mitochondria

Seventh Annual NSF-Funded Solicitation for Tissue Engineering Research Utilizing the ISS National Lab Now Open

A Glimpse Into the World of Bacterial Metabolism Within Hosts

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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