Alzheimer's Disease News and Research

RSS

Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Researchers track how key brain receptor works

For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural signals.

1 Jul 2020

Study can help develop targeted drugs for cancer and other diseases

In the field of molecular biology, chaperones are a group of proteins that help regulate protein folding. Folding is a significant step in protein synthesis.

1 Jul 2020

Study may help design effective treatments for Alzheimer’s disease

Neurons in the brains of such people are being depleted gradually and inevitably, resulting in the characteristic loss of cognitive function and memory.

29 Jun 2020

Subtypes in alzheimer's disease may be linked to tau protein modifications

A new study reveals a possible biological reason that Alzheimer's Disease (AD) progresses at different rates in different patients.

25 Jun 2020

Alzheimer's: New Gene May Drive Earliest Brain Changes

A newly discovered Alzheimer's gene may drive the first appearance of amyloid plaques in the brain, according to a study led by researchers.

23 Jun 2020

Biologists Unravel Tangled Mystery Of Plant Cell Growth

Scientists now understand how a protein called TANGLED1 can lead to accurate cell division in plants.

22 Jun 2020

Disrupted circadian rhythms in older adults linked to increased risk of Parkinson's disease

Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson's disease, according to a new study by scientists at the UC San Francisco Weill Institute for Neurosciences who analyzed 11 years of data for nearly 3,000 independently living older men.

16 Jun 2020

Researchers identify how certain gene mutations cause ALS

Researchers at the University of Maryland School of Medicine have identified how certain gene mutations cause amyotrophic lateral sclerosis, also known as Lou Gehrig's disease.

11 Jun 2020

'Fat burning' molecule holds promise for future treatment and prevention of obesity

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population.

9 Jun 2020

Research team discovers proteins that regulate interorganelle communication

Korea Brain Research Institute (KBRI headed by Suh Pann-ghill) announced on the 2nd that the joint research team of KBRI (team led by Dr. Mun Ji-young), Seoul National University, and Pohang University of Science and Technology discovered the proteins that engage in the formation of MAM, which is the cellular signaling hub.

4 Jun 2020

Stem cell model sheds new light on neurodegeneration process

A new study published today in Neuron led by The New York Stem Cell Foundation Research Institute's Valentina Fossati, Ph.D., creates astrocytes - an integral support cell in the brain - from stem cells and shows that in disease-like environments, these normally helpful cells can turn into neuron-killers.

2 Jun 2020

Toxic tau may spread in the brain via connected neurons

Toxic versions of the protein tau are believed to cause the death of neurons of the brain in Alzheimer's disease.

1 Jun 2020

Gene linked to dementia increases the risk of developing severe COVID-19

Having a faulty gene linked to dementia doubles the risk of developing severe COVID-19, according to a large-scale study.

From University of Exeter 28 May 2020

Researchers design antibody to identify pathogens of Alzheimer's disease

Researchers have found a way to design an antibody that can identify the toxic particles that destroy healthy brain cells - a potential advance in the fight against Alzheimer's disease.

26 May 2020

Innovative two-photon microscopy enables in vivo subcellular imaging of the retina

Retina is the only part of the central nervous system that can be visualized noninvasively with optical imaging approaches.

21 May 2020

Protein modification may cause long-term consequences

Sometimes proteins misfold. When that happens in the human brain, the pileup of misfolded proteins can lead to neurodegenerative diseases like Alzheimer's, Parkinson's and ALS.

20 May 2020

A New Imaging Approach To See Multiple Proteins Simultaneously

Degenerative diseases such as Alzheimer's often involve complex interactions between multiple proteins and other biomolecules.

19 May 2020

Aging neurons build up DNA damage, study finds

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.

18 May 2020

Lipid metabolism enzyme regulates brain stem cell activity

Neural stem cells play a major role in the early development of the brain and they also continue to remain active throughout the lifetime.

11 May 2020

More Berries, Apples And Tea May Have Protective Benefits Against Alzheimer's

Older adults who consumed small amounts of flavonoid-rich foods were two to four times more likely to develop Alzheimer's disease and related dementias.

7 May 2020