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Researchers discover how specific molecules promote cancer progression

The development of cancer is a highly complicated process, involving multiple genes and signaling pathways that become upregulated or downregulated throughout different stages of tumor growth and spread. Two of the most commonly altered genes in cancer are p53 and AKT.

16 Oct 2020

Researchers identify potential drugs that could be repurposed as pan-coronavirus treatments

A large international consortium of almost 200 researchers from 14 leading institutions in six countries has studied three different coronaviruses - SARS-CoV-1, SARS-CoV-2, and MERS-CoV - with the aim of finding vulnerabilities shared by these three pathogens.

16 Oct 2020

Peptide therapy prevents overreaction of the immune system against infections

Individuals require enough action to remove offensive viruses or bacteria, but not so much that their body suffer a considerable damage.

From UC San Diego 15 Oct 2020

Researchers identify drug that could overcome tumor resistance

Scientists have discovered that a drug that may make some melanoma tumors perceptible to the immune system, enabling them to be better targeted.

15 Oct 2020

Researchers demonstrate healing power of extracellular vesicles on a heart-on-a-chip

Extracellular vesicles (EVs) -- nanometer sized messengers that travel between cells to deliver cues and cargo -- are promising tools for the next generation of therapies for everything from autoimmune and neurodegenerative diseases to cancer and tissue injury.

15 Oct 2020

Virus-mimicking drugs may overcome immunotherapy resistance in tumors

Researchers at the UCLA Jonsson Comprehensive Cancer Center have found that a drug that activates the body's natural defenses by behaving like a virus may also make certain stealthy melanoma tumors visible to the immune system, allowing them to be better targeted by immunotherapy.

15 Oct 2020

DNA structural changes play key role in the recovery phase after DNA damage

A research team from Cologne has discovered that a change in the DNA structure - more precisely in the chromatin - plays a decisive role in the recovery phase after DNA damage. The key is a double occupation by two methyl groups on the DNA packaging protein histone H3 (H3K4me2).

15 Oct 2020

Novel mechanism restores cell function after DNA damage

Scientists have found that a modification in the DNA structure— specifically in the chromatin—plays a key role in the recovery stage following DNA damage.

15 Oct 2020

Scientists identify heart cells responsible for repairing damaged heart after infarction

A global study has discovered the heart cells responsible for repairing the damage induced to this vital organ following infarction.

15 Oct 2020

Climate change-driven wildfires cause devastating health impacts

Immediate actions are needed to limit the greenhouse gas emissions that are driving climate change that helps fuel wildfires, a Monash University study says.

14 Oct 2020

Scientists discover key parameters to better predict cancer-killing effect of neoantigens

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

14 Oct 2020

Researchers unravel molecular factors that drive severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

14 Oct 2020

Study shows lasting immunity offered by SARS-CoV-2 antibodies

One of the most significant questions about the novel coronavirus is whether people who are infected are immune from reinfection and, if so, for how long.

14 Oct 2020

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

Natural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have been developed into a novel form of immunotherapy to treat patients with cancer.

14 Oct 2020

Study could explain why some people are severely affected by Bardet-Biedl syndrome

Geneticists usually split disorders into “simple”, where mutations in several genes contribute modest quantities.

13 Oct 2020

Treatment using immune system T cells preserves vision of mice with retinoblastoma

A treatment that uses immune system T cells, combined with an immune-boosting drug packaged in an injectable gel, was found to preserve the vision of mice implanted with tissue from a human eye cancer known as retinoblastoma.

13 Oct 2020

New computational biology algorithm may enable more effective cellular therapies

Cellular therapy is a powerful strategy to produce patient-specific, personalised cells to treat many diseases, including heart disease and neurological disorders. But a major challenge for cell therapy applications is keeping cells alive and well in the lab.

13 Oct 2020

Scientists develop new antimicrobial molecules from toxic proteins in wasp venom

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has engineered powerful new antimicrobial molecules from toxic proteins found in wasp venom.

13 Oct 2020

Research focuses on understanding production of memory B cells and immune responses

The current COVID-19 climate has made vaccines, antibodies, and immune responses topics of everyday conversation. Now, it isn't just immunologists who want to know how our bodies respond to re-infections months, years, or sometimes decades after an initial immune response.

From Osaka University 13 Oct 2020

Gene variations that regulate dopamine levels may influence the mobility of elders

Variations in a gene that regulates dopamine levels in the brain may influence the mobility of elderly and frail adults, according to new research from the University of Pittsburgh Graduate School of Public Health.

13 Oct 2020

Medicine News and Research

Researchers discover how specific molecules promote cancer progression

Researchers identify potential drugs that could be repurposed as pan-coronavirus treatments

Peptide therapy prevents overreaction of the immune system against infections

Researchers identify drug that could overcome tumor resistance

Researchers demonstrate healing power of extracellular vesicles on a heart-on-a-chip

Virus-mimicking drugs may overcome immunotherapy resistance in tumors

DNA structural changes play key role in the recovery phase after DNA damage

Novel mechanism restores cell function after DNA damage

Scientists identify heart cells responsible for repairing damaged heart after infarction

Climate change-driven wildfires cause devastating health impacts

Scientists discover key parameters to better predict cancer-killing effect of neoantigens

Researchers unravel molecular factors that drive severity of COVID-19

Study shows lasting immunity offered by SARS-CoV-2 antibodies

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

Study could explain why some people are severely affected by Bardet-Biedl syndrome

Treatment using immune system T cells preserves vision of mice with retinoblastoma

New computational biology algorithm may enable more effective cellular therapies

Scientists develop new antimicrobial molecules from toxic proteins in wasp venom

Research focuses on understanding production of memory B cells and immune responses

Gene variations that regulate dopamine levels may influence the mobility of elders

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