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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

New report covers challenges and opportunities in gene therapies

Gene therapies are being approved for use in Canada but could strain healthcare budgets and exacerbate existing treatment inequities across the country.

4 Nov 2020

Novel computational method quantifies the coordination level between different genes

Although all humans share similar changes during aging such as gray hair, wrinkles, and a general decline in function, aging is considered to be the result of a cellular wear-and-tear process due to accumulated random damage, such as genetic mutations or DNA structural damage.

4 Nov 2020

Computational method reveals a new hallmark of aging

While all human beings share changes during aging, like wrinkles, gray hair, and a general drop in function, aging is assumed to be the outcome of a cellular process.

4 Nov 2020

Developing a new method to reduce antibiotic resistance in waterways

Dr. Aimee Murray speaks to AZoLifeSciences about her latest research that looks at a way of reducing antibiotic resistance build-up in waterways.

From University of Exeter 4 Nov 2020

Researchers identify evolutionarily conserved pathway responsible for "closing down" gene activity

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a new and evolutionarily conserved pathway responsible for "closing down" gene activity in the mammalian cell.

3 Nov 2020

Root microbiota may play a key role in optimal plant growth

Researchers from the Max Planck Institute for Plant Breeding Research have found that, faced with limiting iron, plants direct their microbiota to mobilize this essential nutrient for optimal growth.

3 Nov 2020

Study shows 1 in 8 cancer patients had inherited cancer-related gene mutation

Genetic testing can uncover inherited genetic mutations, and could individualize cancer therapies, improve survival, manage cancer in loved ones and push the boundaries of precision medicine.

3 Nov 2020

Study reveals proteins that enable SINEUPs to increase protein production

Scientists from an international group led by the RIKEN Center for Integrative Medical Sciences and Yokohama City University have discovered that a pair of proteins play a key role in allowing an important type of functional non-coding RNA, known as SINEUPs, to act to promote their target messenger RNA.

2 Nov 2020

Reducing food intake can reduce risk of liver cancer caused by fatty liver

Liver cancer from too much fat accumulation in the liver has been increasing in many countries including Japan. In order to change this unfortunate state of affairs, it is important to improve the prognosis of non-alcoholic fatty liver disease.

2 Nov 2020

Study identifies genes and molecular pathways most sensitive to chemical exposures

A University of Massachusetts Amherst environmental health scientist has used an unprecedented objective approach to identify which molecular mechanisms in mammals are the most sensitive to chemical exposures.

30 Oct 2020

Researchers find genetic correlations between inflammatory bowel disease and stress, depression

Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies (GWAS), researchers at Children's Hospital of Philadelphia (CHOP) have found significant genetic correlations between inflammatory bowel disease (IBD) and stress and depression.

30 Oct 2020

'Training’ the innate immunity may improve the success of immunotherapy

Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer. Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, the T cells and B cells that respond to specific threats to the body.

30 Oct 2020

Research projects receive BTCA awards to develop new drugs

Five research projects with exceptional promise to deliver new life-changing and health-altering therapies have received the inaugural Blavatnik Therapeutics Challenge Awards (BTCA) at Harvard Medical School.

From Harvard Medical School 30 Oct 2020

Scientists sequence full genome of ornamental variety of miscanthus

An international research team has sequenced the full genome of an ornamental variety of miscanthus, a wild perennial grass emerging as a prime candidate for sustainable bioenergy crops.

30 Oct 2020

Scientists discover link between two signaling pathways crucial to growth of colon cancer

In breakthrough colon cancer research, scientists at ChristianaCare's Helen F. Graham Cancer Center & Research Institute have discovered a link between two key signaling pathways crucial to the development and growth of colon cancer. The study is published today in the journal PLOS ONE.

29 Oct 2020

Genetic predispositions affect the efficacy of COVID-19 drugs

A paper recently uploaded to bioRxiv* aimed to utilize genome-wide CRISPR screening to identify genes involved in modulating the activity of COVID-19 drugs.

29 Oct 2020

Study shows how cancer remodels human chromosomes for its own purposes

Scientists have shown that cancer rebuilds the architecture of human chromosomes, which allows the disease to take hold and spread.

28 Oct 2020

RNA-centric mechanism regulates microRNAs linked to cancer, neurological disorders

MicroRNAs are small non-coding RNAs—that is, bits of genetic code that act as key gene regulators in various aspects of biological processes.

28 Oct 2020

Researchers map molecular structure of CV30 antibody to neutralize coronavirus

Scientists at Fred Hutchinson Cancer Research Center in Seattle have shown that a potent antibody from a COVID-19 survivor interferes with a key feature on the surface of the coronavirus's distinctive spikes and induces critical pieces of those spikes to break off in the process.

28 Oct 2020

Study shows genetic analysis with RNA sequencing can increase diagnostic yield

In the world of rare genetic diseases, exome and genome sequencing are two powerful tools used to make a diagnosis.

28 Oct 2020

Gene News and Research

Further Reading

New report covers challenges and opportunities in gene therapies

Novel computational method quantifies the coordination level between different genes

Computational method reveals a new hallmark of aging

Developing a new method to reduce antibiotic resistance in waterways

Researchers identify evolutionarily conserved pathway responsible for "closing down" gene activity

Root microbiota may play a key role in optimal plant growth

Study shows 1 in 8 cancer patients had inherited cancer-related gene mutation

Study reveals proteins that enable SINEUPs to increase protein production

Reducing food intake can reduce risk of liver cancer caused by fatty liver

Study identifies genes and molecular pathways most sensitive to chemical exposures

Researchers find genetic correlations between inflammatory bowel disease and stress, depression

'Training’ the innate immunity may improve the success of immunotherapy

Research projects receive BTCA awards to develop new drugs

Scientists sequence full genome of ornamental variety of miscanthus

Scientists discover link between two signaling pathways crucial to growth of colon cancer

Genetic predispositions affect the efficacy of COVID-19 drugs

Study shows how cancer remodels human chromosomes for its own purposes

RNA-centric mechanism regulates microRNAs linked to cancer, neurological disorders

Researchers map molecular structure of CV30 antibody to neutralize coronavirus

Study shows genetic analysis with RNA sequencing can increase diagnostic yield

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