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Unraveling the Rhizobia-Diatom Relationship in the Ocean

Nitrogen is an essential component of all living organisms. It is also the key element controlling the growth of crops on land, as well as the microscopic oceanic plants that produce half the oxygen on our planet.

10 May 2024

Understanding Genome Scrambling in Oikopleura Dioica

When two animals look the same, eat the same, behave the same way, and live in similar environments, one might expect that they belong to the same species.

10 May 2024

Decoding Aging: The Role of Stochastic Variation in Biological Clocks

Aging clocks can measure the biological age of humans with high precision. Biological age can be influenced by environmental factors such as smoking or diet, thus deviating from the chronological age that is calculated using the date of birth.

10 May 2024

New Tool Precisely Edits Epigenetic Modifications

Powerful epigenetic editing technology was developed as a result of research by the Hackett group at EMBL Rome. This technology allows for the precise programming of chromatin modifications.

10 May 2024

Researchers Uncover New Genetic Mutation Linked to Rare Form of Congenital Thyroid Abnormality

A team of researchers from the University of Chicago, in collaboration with the Free University of Brussels and the University of Washington, have uncovered a genetic mutation in a non-coding region of DNA that alters the regulation of the thyroid, leading to a rare form of congenital thyroid abnormality.

9 May 2024

Cooperative Synthesis of Vitamin B12 by Marine Bacterial Partners

A German-American research team led by microbiologist Dr Gerrit Wienhausen from the University of Oldenburg (Germany) has come an important step closer to a better understanding of highly complex interactions between marine microorganisms.

9 May 2024

Rice University Develops AI-Powered Tools for Unraveling Microbial Genomes

Since the first microbial genome was sequenced in 1995, scientists have reconstructed the genomic makeup of hundreds of thousands of microorganisms and have even devised methods to take a census of bacterial communities on the skin, in the gut, or in soil, water and elsewhere based on bulk samples, leading to the emergence of a relatively new field of study known as metagenomics.

8 May 2024

New Insights Into PARP1 Biology Could Open Avenues to Improve Cancer Treatments

A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of chromosomes, and that impairing this process can lead to telomere shortening and genomic instability that can cause cancer.

8 May 2024

Unlocking Glucose-Driven Mechanisms of Immunosuppression in Glioblastoma

The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma -; a serious and often fatal brain cancer -; suppresses the immune system so that the tumor can grow unimpeded by the body's defenses.

6 May 2024

Epigenomic Analysis Reveals Potential Treatment Avenues for ALS

For most patients, it's unknown exactly what causes amyotrophic lateral sclerosis (ALS), a disease characterized by degeneration of motor neurons that impairs muscle control and eventually leads to death.

3 May 2024

New Study Sheds Light on Genetic Adaptations of Papua New Guinean Populations

Papua New Guinea (PNG) has a wide range of environments, each presenting unique challenges to human survival. Highlanders and lowlanders of PNG are striking examples of populations facing distinct environmental stress.

2 May 2024

St. Jude Scientists Reveal Role of Non-Coding DNA Variants in Childhood Leukemia

St. Jude Children's Research Hospital scientists have identified specific DNA variants in the non-coding regions of the genome contributing to chemotherapy resistance in acute lymphoblastic leukemia (ALL).

2 May 2024

New Method Sheds Light on How Protein Modifications Power T Cells

Imagine riding a bike. Now imagine riding a bike with an enormous beach ball stuck on your handlebars. That "modification" might change your experience quite a bit.

30 Apr 2024

Investigating Enhancer Function in Pluripotent Stem Cells

As embryos, all complex organisms are partially made up of pluripotent stem cells, a term for cells that have the capacity to differentiate into any kind of cell: nerve cells, muscle cells, blood cells, skin cells, and the like.

30 Apr 2024

UNC Researchers Create Key Tool for Kaposi Sarcoma Drug Development

Researchers at UNC Lineberger Comprehensive Cancer Center, after decades of research efforts, have developed a mouse model of Kaposi sarcoma that could be key to the development of new drugs to treat the disease.

30 Apr 2024

AI Models Predict Plant Gene Activity with Unprecedented Precision

Genome sequencing technology provides thousands of new plant genomes annually. In agriculture, researchers merge this genomic information with observational data (measuring various plant traits) to identify correlations between genetic variants and crop traits like seed count, resistance to fungal infections, fruit color, or flavor.

30 Apr 2024

Genetic Insights: Safflower Genome Assembly Unlocks Key Traits for Crop Improvement

A research team completes a high-quality chromosome-scale assembly of the 'Chuanhonghua 1' safflower genome.

30 Apr 2024

Study Reveals Molecular Assembly of One of the Most Common Anti-Phage Systems

One of the many secrets to bacteria's success is their ability to defend themselves from viruses, called phages, that infect bacteria and use their cellular machinery to make copies of themselves.

29 Apr 2024

Research Reveals Surprising Insights Into Yeast Evolution

University of North Carolina at Charlotte Assistant Professor of Bioinformatics Abigail Leavitt LaBella has co-led an ambitious research study -; published this week in the widely influential journal Science -; that reports intriguing findings made through innovative artificial intelligence analysis about yeasts, the small fungi that are key contributors to biotechnology, food production and human health.

29 Apr 2024