Metabolites News and Research

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Genetic analysis reveals the inhibitory role of NSD2 enzyme in cellular senescence

Using a detailed genetic analysis, a research team from Japan-based Kumamoto University has discovered that the NSD2 enzyme, which controls the actions of several genes, also functions to block the aging of cells.

10 Aug 2020

Study may help identify women at risk of developing type 2 diabetes after pregnancy

Researchers have discovered that lipid metabolism is disrupted after childbirth in women suffering from gestational diabetes, who subsequently develop type 2 diabetes.

From University of Toronto 6 Aug 2020

Study uncovers molecular mechanism of metabolite-mediated epigenome involved in organismal aging

Scientists have recently demonstrated that acetyl-CoA connects mitochondrial stress to the nuclear epigenome through the NuRD complex.

4 Aug 2020

Researchers show how gut microbiomes change the nature of cancer mutations

It is a fact that has long baffled doctors: Cancer in the small intestine is quite rare, whereas colorectal cancer, a neighboring though much smaller organ, is one of the leading causes of cancer death for men and women. What is it about the colon that seems to "attract" cancer?

30 Jul 2020

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

Boosting metabolic resources in the brain could be a way to slow neurodegeneration

Researchers at Vanderbilt University Medical Center have shown for the first time that when one optic nerve in the eye is damaged, as in glaucoma, the opposite optic nerve comes to the rescue by sharing its metabolic energy.

From Vanderbilt University 22 Jul 2020

Environmental pollutants pose risks to finless porpoises

A new study has revealed that environmental pollutants pose toxicological risks to finless porpoises (Neophocaena asiaeorientalis).

21 Jul 2020

Study: Specific mechanism of Cyclocarya paliurus shows promise for treating type 2 diabetes

Type 1 diabetes mellitus and type 2 diabetes mellitus (T2DM) are the two main types of diabetes, while T2DM accounts for 90%-95% of those with diabetes.

14 Jul 2020

Metabolomics can help understand the impact of calorie-restricted diets on aging

Changes in a few small molecules involved in a cell's metabolism seem to indicate whether a restricted "life extension" diet will actually extend, shorten, or have no effect on lifespan, a study of fruit flies has found.

10 Jul 2020

Researchers solve a controversial question in photosynthesis

The research team has devised novel approaches to observe energy changes that occur in subcellular compartments in live plants.

1 Jul 2020

Pseudotargeted metabolomics method can help analyze bile and amino acids

A team of researchers has come up with a procedure through which the pseudotargeted metabolomics technique can be systematically summarized and upgraded.

29 Jun 2020

Researchers discover unknown enzyme activity towards human endogenous substrates

Scientists have identified an enzymatic activity towards common drugs as well as significant human endogenous substrates, that was previously not known.

24 Jun 2020

Five-minute urine test measures quality of people's diets

Scientists have completed large-scale tests on a new type of five-minute urine test that measures the health of a person's diet, and produces an individual's unique urine 'fingerprint'.

23 Jun 2020

Study reveals mechanism by which propionic acid induces brain disorders

Korea Brain Research Institute (KBRI, headed by Suh Pann-ghill) announced on the 11th that the research team led by Dr. Mun Ji-young revealed the mechanism of autism induced by an imbalance of human gut microorganisms.

19 Jun 2020

Camelina sativa oil and fatty fish have major positive effect on lipid metabolism

Camelina sativa oil and fatty fish are rich in polyunsaturated omega-3 fatty acids, but their health benefits seem to differ.

17 Jun 2020

Remodeling of gut microbiome strongly inhibits thickened-artery condition in mice

Scientists at Scripps Research have developed molecules that can remodel the bacterial population of intestines to a healthier state and they have shown--through experiments in mice--that this reduces cholesterol levels and strongly inhibits the thickened-artery condition known as atherosclerosis.

16 Jun 2020

Metabolites News and Research

Genetic analysis reveals the inhibitory role of NSD2 enzyme in cellular senescence

Study may help identify women at risk of developing type 2 diabetes after pregnancy

Study uncovers molecular mechanism of metabolite-mediated epigenome involved in organismal aging

Researchers show how gut microbiomes change the nature of cancer mutations

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

Boosting metabolic resources in the brain could be a way to slow neurodegeneration

Environmental pollutants pose risks to finless porpoises

Study: Specific mechanism of Cyclocarya paliurus shows promise for treating type 2 diabetes

Metabolomics can help understand the impact of calorie-restricted diets on aging

Researchers solve a controversial question in photosynthesis

Pseudotargeted metabolomics method can help analyze bile and amino acids

Researchers discover unknown enzyme activity towards human endogenous substrates

Five-minute urine test measures quality of people's diets

Study reveals mechanism by which propionic acid induces brain disorders

Camelina sativa oil and fatty fish have major positive effect on lipid metabolism

Remodeling of gut microbiome strongly inhibits thickened-artery condition in mice

High sodium intake affects health of gut microbiome

Study reveals new insight on vaccines and antimicrobials

New tool shows how microbes influence health and promote diseases

Chemists Develop Foolproof New Test To Track The Fats We Eat

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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