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Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.

29 Mar 2023

Determining the structure of protein pumps using cryo-EM

A rare, genetic disorder known as Hailey-Hailey disease causes patches of blisters to develop mainly in the folds of skin under the breasts, in the groin, and the armpits.

29 Mar 2023

Human cells shed light on basic squid biology

Squids and octopuses are masters of camouflage, blending into their environment to evade predators or surprise prey.

28 Mar 2023

No more needles? Future vaccines could be delivered by a puff of air

In the future, vaccines may be delivered with a puff of air rather than a needle, according to the promising results of new research presented at a meeting of the American Chemistry Society this March.

27 Mar 2023

Innovative new approach to constructing a nose in young patients with arhinia

Congenital arhinia (meaning patients born without a nose) is a rare condition associated with high mortality if not identified.

24 Mar 2023

Immunity adaptation found in genomes of Stone Age farmers

New research suggests that diversity in genes implicated in immunity might have facilitated the shift from hunter-gatherer lifestyles to agriculture that occurred in prehistoric Europe over the course of around 1,500 years.

23 Mar 2023

Single mechanosensitive protein shown to contribute to fibrosis in multiple organs

Researchers from Kyushu University have found how a single mechanosensitive protein induces the process that thickens and scars tissue, known as fibrosis. The protein, called VGLL3, was shown to contribute to fibrosis in multiple organs.

23 Mar 2023

Researchers discover a new intracellular "smoke detector"

Researchers at the Universities of Bonn and Singapore have discovered a new intracellular "smoke detector." The sensor warns of damage to the mitochondria - the microscopic power plants that supply the cell with energy.

22 Mar 2023

Emergence and spread of a deadly fungus among African amphibians

For the past few years, how a virus triggered a global pandemic has dominated conversations. Now, thanks to the TV show "The Last of Us" (about an apocalypse triggered by brain-eating 'shrooms), fungi have infected popular culture.

16 Mar 2023

Influence of molecular component of caffeine on gut health

Certain microbes are considered to play a role in the development of inflammatory disorders such as inflammatory bowel disease (IBD).

16 Mar 2023

Study examines the role of dietary vitamin A in preventing or treating AAP

Consuming a diet rich in vitamin A or its analogs may help prevent children and young adults with acute lymphoblastic leukemia (ALL) reduce their risk of developing painful pancreas inflammation during chemotherapy treatment.

16 Mar 2023

Study evaluates the risk posed by the fungus Bd to amphibians across the continent of Africa

Mass fungus infections that drive populations worldwide to near-collapse don't just occur in science fiction. Chytridiomycosis, the worst vertebrate disease in recorded history, has already wiped out hundreds of species of amphibians around the world. Due to a large part to this fungal disease, 41% of amphibians are currently threatened with extinction. Only species living in Africa seemed to have been relatively spared from the scourge of chytridiomycosis – at least so far.

15 Mar 2023

Novel technology easily detects active Mycobacterium tuberculosis infection antibodies

A team of faculty from Wayne State University has discovered new technology that will quickly and easily detect active Mycobacterium tuberculosis (TB) infection antibodies.

14 Mar 2023

Study identifies previously unknown cell types that drive the onset of osteoarthritis

A Michigan Medicine study has identified a new potential target for treating osteoarthritis – a debilitating joint disease that affects over 31 million Americans and is a leading cause of disability worldwide.

10 Mar 2023

Study shows mothers provide necessary microbes to babies born via cesarean

Can newborns delivered by cesarean surgery lack vital microbes? Recent data suggests that “no” could be the answer. Mothers are able to transmit bacteria to their babies through alternative, compensating channels, according to research published in the journal Cell Host & Microbe on March 8th, 2023.

10 Mar 2023

Study identifies a novel rare mutation in gene linked to Harlequin Ichthyosis

Harlequin ichthyosis (HI) is a severe genetic skin disorder characterized by thick white, brown, or dark brown patches on the skin covering a newborn's entire body. HI has a low incidence of 1 per 300,000 live births but comes with the highest mortality rate among skin conditions. It is caused by a mutation in the ABCA12 gene, which codes for a protein involved in transporting lipids necessary for the formation of the skin barrier. Such protein shortage leads to a weaker epidermal barrier.

9 Mar 2023

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Using nanoparticles to carry drugs across the blood-brain barrier

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023

Novel way to block the death of nerve cells in MND

Scientists have found a novel way to block the transportation of mutant RNA and subsequent production of toxic repeat proteins which lead to the death of nerve cells in the most common subtypes of motor neurone disease (MND) and frontotemporal dementia (FTD).

2 Mar 2023

Disinfecting water with peptide-coated silver sulfide quantum dots

Water contaminated with bacteria poses a serious threat to global health. In the scientific publication Angewandte Chemie, a Chinese research team developed a simple new technique for disinfection.

1 Mar 2023

Skin News and Research

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Determining the structure of protein pumps using cryo-EM

Human cells shed light on basic squid biology

No more needles? Future vaccines could be delivered by a puff of air

Innovative new approach to constructing a nose in young patients with arhinia

Immunity adaptation found in genomes of Stone Age farmers

Single mechanosensitive protein shown to contribute to fibrosis in multiple organs

Researchers discover a new intracellular "smoke detector"

Emergence and spread of a deadly fungus among African amphibians

Influence of molecular component of caffeine on gut health

Study examines the role of dietary vitamin A in preventing or treating AAP

Study evaluates the risk posed by the fungus Bd to amphibians across the continent of Africa

Novel technology easily detects active Mycobacterium tuberculosis infection antibodies

Study identifies previously unknown cell types that drive the onset of osteoarthritis

Study shows mothers provide necessary microbes to babies born via cesarean

Study identifies a novel rare mutation in gene linked to Harlequin Ichthyosis

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Using nanoparticles to carry drugs across the blood-brain barrier

Novel way to block the death of nerve cells in MND

Disinfecting water with peptide-coated silver sulfide quantum dots

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