Efficacy News and Research

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Yeast platform for the production of plant-derived anti-cancer drug

The supply of a plant-derived anti-cancer drug can finally meet global demand after a team of scientists from Denmark and the U.S. engineered yeast to produce the precursor molecules, which could previously only be obtained in trace concentrations in the native plant.

1 Sep 2022

Therapeutic mRNAs do not significantly impact translational fidelity

Synthetic mRNA therapeutics for the treatment and prevention of disease has attracted a lot of interest due to the exceptional efficacy of mRNA vaccinations against SARS-CoV-2.

30 Aug 2022

Researchers identify microbes that influence sorghum development during drought

Drought is one of the greatest threats to agricultural systems, resulting in unpredictable crop yields, declines in farm revenue, and an increase in disease outbreaks.

24 Aug 2022

Extract from the roots of Rhodiola rosea may be effective for managing type 2 diabetes

A team of researchers led by the University of California, Irvine has discovered that treatment with an extract from the roots of the Rhodiola rosea plant might be effective for helping manage type 2 diabetes, showing promise as a safe and effective non-pharmaceutical alternative.

16 Aug 2022

Evonetix commences early access program for DNA synthesised by thermal control on its semiconductor chip

Researchers are invited to apply to receive DNA that has been synthesised using Evonetix’s platform.

From Evonetix 16 Aug 2022

Study finds a nutrition-based solution to restore milk production during warm weather

Rising temperatures pose major challenges to the dairy industry – a Holstein's milk production can decline 30 to 70% in warm weather – but a new Cornell University-led study has found a nutrition-based solution to restore milk production during heat-stress events, while also pinpointing the cause of the decline.

8 Aug 2022

New sample pre-treatment method enables efficient protein recovery

The cells’ proteins contain a huge world of information that, when unlocked, can shed light on the causes of many fundamental biological occurrences. To observe the properties of individual cells at the protein level, a single-cell analysis method known as “single-cell proteomics” is used.

8 Aug 2022

Researchers develop targeted immunotherapy to destroy tumor cells

A minimally invasive technique was created and improved by scientists at Terasaki Institute for Biomedical Innovation (TIBI) to develop immunotherapeutic cancer treatments.

3 Aug 2022

A Retro-Cascorder device records a cell’s genetic activity in DNA for days at a time

If you want to keep track of someone’s activities for a day, contact them every 10 minutes and inquire what they are up to. It would be simpler, though, to equip them with a journal in which to record their own acts.

1 Aug 2022

Researchers propose a solution to delayed molecular diagnosis and therapy in childhood genetic diseases

Rady Children’s Institute for Genomic Medicine (RCIGM®) recently announced the publication in Nature Communications of research that describes and examines the efficiency of Genome-to-Treatment (GTRxTM), a computer-controlled, virtual disease management system that combines a quick Whole Genome Sequencing (rWGS®) diagnosis accomplished in 13.5 hours with a custom lab management information system and analysis pipeline.

28 Jul 2022

Study finds broadly neutralizing antibodies might help to treat or cure HIV infection

According to research, carefully formulated combinations of broadly neutralizing antibodies might effectively cure HIV while reducing the chance that the virus would evade therapy.

22 Jul 2022

Researchers work on DNA-delivered antibodies to stop COVID-19

A new COVID-19 antibody delivery approach has progressed to clinical trials, thanks to funding from the Defense Advanced Research Projects Agency (DARPA) and the Joint Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (JPEO-CBRND).

11 Jul 2022

A new study analyzes antimicrobial detergents and textile chemicals in homes

The use of less bleach and lower temperatures over washing machine cycles is promoted as a result of shifting societal attitudes toward the environment.

8 Jul 2022

How Important is the European Ecosystem to Life Sciences Research?

As part of our SLAS Europe 2022 coverage, we speak to Jan Lichtenberg, vice president of SLAS, about the role Europe plays within life sciences research.

From Society for Laboratory Automation and Screening (SLAS) 7 Jul 2022

Study shows how drugs help to treat hepatitis A virus replication using an animal model

A virus must go through the viral replication cycle in order to propagate throughout the body and cause disease.

5 Jul 2022

Small, flexible implant relieves pain on demand and without the use of drugs

A Northwestern University-led team of researchers has developed a small, soft, flexible implant that relieves pain on demand and without the use of drugs.

4 Jul 2022

Researchers discover effective therapy for pediatric T-acute leukemia

The most frequent type of malignancy in kids is acute lymphoblastic leukemia (ALL).

27 Jun 2022

Researchers reveal how blood serum impacts the survival and metabolism of bacteria

In hospitals, the Staphylococcus aureus bacteria can be transported from the skin or nasal cavity into open wounds and, possibly, the bloodstream, posing a fatal hazard. Staph infections killed over 20,000 Americans in 2017, according to the Centers for Disease Control and Prevention.

20 Jun 2022

Spirea raises £2.4M ($3M) to develop antibody drug conjugates in cancer

Funding will enable the development of Spirea’s pipeline of antibody drug conjugate therapeutics for the treatment of solid tumours.

From Spirea 14 Jun 2022

Researchers discover a new interferon-gamma receptor signaling pathway

The interferon-gamma receptor (IFNgR) signaling pathway has been identified to be crucial for the vulnerability of glioblastoma tumors to death by CAR T-cell immunotherapy, according to researchers at Massachusetts General Hospital (MGH).

10 Jun 2022