Preclinical News and Research

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Making opioids safer and more effective

Dr. John Streicher speaks to AZoLifeSciences about his research on improving opioid drugs to make them safer and more effective.

From University of Arizona 28 May 2020

A 'Switch' That Turns Autoimmunity Drugs Into Powerful Anti-Cancer Treatments

Scientists have discovered a way to transform antibody drugs into antibodies with powerful anti-cancer activity through a simple molecular "switch".

22 May 2020

Cell-culture based in vitro test systems for screening of antitumor drugs

As we know, a malignant tumor is a complex system of mutated cells which constantly interacts with and involves healthy cells in the body.

21 May 2020

Texas A&M lab produces 3D-bioprinted bone tissues

Dr. Akhilesh K. Gaharwar, associate professor, has developed a highly printable bioink as a platform to generate anatomical-scale functional tissues. This study was recently published in the American Chemical Society's Applied Materials and Interfaces.

20 May 2020

Breaking Down the DNA Behavior of Cancer Cells

Dr. Manel Esteller speaks to AZoLifeSciences about his ground-breaking cancer research in which he uncovered the behavior of DNA in 3D models.

From University of Barcelona 13 May 2020

New DNA study can revolutionize cancer treatment

In a new study, researchers have used 3D models to disintegrate the DNA behavior of tumor cells, paving the way for innovative treatment for the disease.

11 May 2020

Novel mechanism allows the immune system to control autoimmunity, cancer

Scientists at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) revealed a novel mechanism through which the immune system can control autoimmunity and cancer.

7 May 2020

Anti-cancer medicine could improve current therapy for ER+ breast cancer

The anti-cancer medicine venetoclax could improve the current therapy for estrogen receptor-positive (ER+) breast cancer - the most common form of breast cancer in Australia - according to preclinical studies led by Walter and Eliza Hall Institute researchers.

7 May 2020

Nanostimulators Boost Stem Cells For Muscle Repair

In medicine, a treatment for patients whose muscles are damaged from lack of oxygen would be to invigorate them with an injection of their own stem cells.

4 May 2020

Antibodies From Llamas Could Help In Fight Against COVID-19

The hunt for an effective treatment for COVID-19 has led one team of researchers to find an improbable ally for their work: a llama named Winter.

30 Apr 2020

New Type Of Immune Cell Discovered In Breast Ducts

Melbourne breast cancer researchers have discovered a new type of immune cell that helps to keep breast tissue healthy by regulating a vital process.

28 Apr 2020

Developing novel compounds that inhibit SARS-CoV-2 main protease

A research team from China has now created two novel compounds that block the SARS-CoV-2 main protease (Mpro).

23 Apr 2020

Autoimmunity Plays A Role In Parkinson's Disease

A new study co-led by scientists at the La Jolla Institute for Immunology (LJI) adds increasing evidence that Parkinson's disease is partly an autoimmune disease.

20 Apr 2020

Unlocking New Ways To Understanding Evolving Strains Of SARS-Cov-2

Researchers from CSIRO have unveiled a new approach to analyzing the genetic codes - or the blueprint - of the SARS-CoV-2 virus that causes COVID-19.

20 Apr 2020

Largest proteomic study reveals link between glucose metabolism proteins and AD biology

In the largest study to date of proteins related to Alzheimer's disease, a team of researchers has identified disease-specific proteins and biological processes that could be developed into both new treatment targets and fluid biomarkers.

13 Apr 2020