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Harbour BioMed and Insilico Collaborate on Advanced AI-Driven Antibody Discovery

Harbour BioMed (HKEX: 02142, the "Company"), a global biopharmaceutical company committed to the discovery, development and commercialization of novel antibody therapeutics focusing on immunology and oncology, and Insilico Medicine ("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, today announced a strategic collaboration to accelerate the discovery and development of innovative therapeutic antibodies, leveraging their respective technological strengths in antibody discovery and artificial intelligence.

22 Feb 2025

Zinc-Carrying Proteins Activate Proton Pump Inhibitors in Neutral Environments

Acid reducing medicines from the group of proton pump inhibitors (PPIs) are best-selling drugs that prevent and alleviate stomach problems.

22 Feb 2025

LUC7 Proteins Play Key Role in RNA Splicing Control

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut out and the coding portions are spliced back together.

21 Feb 2025

Targeting NMDA Receptor Subunit Shows Promise for Fragile X Syndrome

Building on more than two decades of research, a study by MIT neuroscientists at The Picower Institute for Learning and Memory reports a new way to treat pathology and symptoms of fragile X syndrome, the most common genetically-caused autism spectrum disorder.

21 Feb 2025

New 3D Lung Model Offers Personalized Aerosol Therapeutic Insights

Respiratory diseases are a challenging problem to treat. Inhalable medicines are a promising solution that depend on the ability to deliver tiny particles known as aerosols to the correct location in the lungs at the correct dosage.

21 Feb 2025

Can Bacteria Left Behind During Intercourse Serve as Forensic Evidence?

Microbial signatures transferred during intercourse offer a new forensic tool, detectable even with condom use, enhancing evidence in sexual assault cases.

21 Feb 2025

Researchers Unveil Process Behind Cellular Recycling and Waste Removal

A new discovery from an international collaborative research team has solved the mystery of how cells turn on their recycling process and create ‘garbage bags’ to remove proteins.

21 Feb 2025

New Discoveries Challenge Textbook Knowledge of Mitochondrial Respiration

In an article published in the journal Trends in Biochemical Sciences, Alicia Kowaltowski, full professor at the University of São Paulo's Institute of Chemistry (IQ-USP) in Brazil, advocates the "rewriting" of textbooks on the location of the electron transport chain in mitochondria and the role of sodium in mitochondrial respiration.

20 Feb 2025

Immunotherapy Breakthrough Targets Jumbled Proteins in Glioma

Immune therapy has transformed how cancer is treated, but many tumors continue to evade these treatments, thanks to their resemblance to healthy tissue.

20 Feb 2025

Study Reveals How the Brain Gauges Risk and Reward in Decision-Making

Every day, our brain makes thousands of decisions, big and small. Any of these decisions - from the least consequential such as picking a restaurant to the more important such as pursuing a different career or moving to a new city - may result in better or worse outcomes.

20 Feb 2025

Dysfunctional Memory B Cells Identified as Key Cancer Therapy Target

University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood – known as the tertiary lymphoid structure – where they become frustratingly dysfunctional when in close contact with tumors.

20 Feb 2025

Novel Mechanism of mRNA Transfer via Tunneling Nanotubes Discovered

Cell-to-cell communication is crucial in all forms and stages of life, and various communication mechanisms have been extensively researched.

20 Feb 2025

New Approach to Cancer Treatment Through Nutrient Deprivation

Scientists had previously ignored the cooperative method by which cancer cells obtain nutrients from their surroundings, but it may be a promising target for cancer treatment.

20 Feb 2025

CRISPR Unlocks the Secrets of Flowering in Plants

For generations, humans have loved the beauty of flowers. However, flowers are more than just visually appealing. They also play an important role in plant reproduction.

20 Feb 2025

CRISPR Unlocks ‘Sleeping’ Genes—A Potential Cure for Prader-Willi Syndrome?

CRISPR epigenome editing successfully reactivates silenced genes in Prader-Willi Syndrome, highlighting potential for targeted therapies in genetic disorders.

20 Feb 2025

New Insights into How MicroRNA Affects Bird Flu in Wildlife

Previously, researchers thought that microRNA was a kind of useless residue in cells and blood. But these tiny threads are far more important than some imagined. Also for those who study wildlife.

19 Feb 2025

Blocking Cholesterol Metabolite May Prevent Parkinson's Disease Progression

Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice.

19 Feb 2025

Genetic Factors Play a Key Role in Eye Aging and Disease

Vision changes are an inevitable part of aging, but why are some more susceptible to age-related eye diseases and why do some individuals experience more severe decline than others?

19 Feb 2025

Unlocking the Genetic Secrets Behind Human Vocal Communication

The origins of human language remain mysterious. Are we the only animals truly capable of complex speech? Are Homo sapiens the only hominids who could give detailed directions to a far-off freshwater source or describe the nuanced purples and reds of a dramatic sunset?

19 Feb 2025

Study Explores Genetic Predictors of Prostate Cancer Progression

A recent study published in the Journal of Cancer Research and Clinical Oncology explored genetic predictors of prostate cancer progression to help identify its clinical outcomes.

19 Feb 2025