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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

Lasting nature of IBD linked to long-lived immune cell that causes persistent inflammation

Inflammatory bowel disease (IBD) is a group of intestinal disorders affecting an estimated six to eight million people worldwide.

25 Aug 2020

Fault in RNA quality control system causes haywire production of toxic proteins

Osaka, Japan - Researchers at Osaka University have identified a fault in the RNA quality control system of cells that leads to the haywire production of toxic proteins in frontotemporal lobar degeneration and amyotrophic lateral sclerosis (FTLD/ALS).

From Osaka University 25 Aug 2020

Lipid-based nanoparticles can help treat genetic disorders

Introducing genetic material into the body to treat diseases can work, but making sure that those materials are safely sent to the right location is complicated.

24 Aug 2020

Study shows Annexin molecule promotes resistance to anticancer drugs

Headed by Kumamoto University (Japan), a collaborative study has identified a novel mechanism for anticancer drug resistance in gastric cancer.

24 Aug 2020

Study shows how DUSP8 protein regulates glucose tolerance, insulin sensitivity

The brain plays a major role in controlling our blood glucose levels. In type 2 diabetics this glucose metabolism brain control is often dysfunctional. Genetic components for this phenomenon have so far remained elusive.

24 Aug 2020

Researchers develop multiplex genetic diagnostic device for early detection, prevention of crop diseases

A research group composed of Professor Takayuki Shibata and his colleagues at the Department of Mechanical Engineering, Toyohashi University of Technology has applied a microfluidic chip technology to develop a multiplex genetic diagnostic device for the early detection and prevention of crop diseases.

24 Aug 2020

Eliminating tumors with engineered ‘off-the-shelf’ therapeutic T cells

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors

21 Aug 2020

Master regulator genes of asthma identified

Researchers identify master regulator genes of asthma, provide new path forward in the study of asthma and the development of novel therapies.

21 Aug 2020

Genetic background influences cancer risk in individuals with single-gene variants

Life can change dramatically when someone learns they are genetically predisposed to a disease, such as a condition called familial hypercholesterolemia, where a mutated gene can lead to elevated cholesterol and increased risk for a premature heart attack.

21 Aug 2020

Study explains how epigenetic factors relate to aging

According to a study, headed by a psychologist at the University of California, genetic background may influence how people adapt to aging in late life.

20 Aug 2020

Small set of genes may help decide the identity of every neuron in worms

When it comes to brain cells, one size does not fit all. Neurons come in a wide variety of shapes, sizes, and contain different types of brain chemicals.

20 Aug 2020

Study reveals a mechanism for lower-quality immune response in patients with severe COVID-19

The release of massive amounts of proteins called cytokines can lead to some of the most severe symptoms of COVID-19.

From Harvard Medical School 20 Aug 2020

Cashew shell compound shows therapeutic potential for demyelinating diseases

In laboratory experiments, a chemical compound found in the shell of the cashew nut promotes the repair of myelin, a team from Vanderbilt University Medical Center reports today in the Proceedings of the National Academy of Sciences.

From Vanderbilt University 19 Aug 2020

Gene targeting could lead to better treatment of glioblastoma tumors

New insight into a gene that controls energy production in cancer stem cells could help in the search for a more effective treatment for glioblastoma.

19 Aug 2020

New tumor gene test could help predict survival of women with ovarian cancer

A global team of medical researchers led by UNSW have developed a test that could help to predict survival for women diagnosed with ovarian cancer, and pave the way towards personalised treatment.

From The University of New South Wales (UNSW) 19 Aug 2020

Researchers study how bacteria adapt to their host cells

In the environment, they are often found inside unicellular organisms. A research team led by Matthias Horn at the Centre for Microbiology and Environmental Systems Science at the University of Vienna has made use of laboratory experiments to gain a better understanding of how these bacteria adapt to their host cell over time.

19 Aug 2020