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Identification of genetic variant provides a big step for precision medicine in dialysis

Every day, the human kidneys clean about 1,500 liters of blood by producing approximately 1–2 liters of urine. Thereby, the body gets rid of excess water and toxic waste products of the metabolism or also drugs and maintains the balance of water and minerals in the tissues.

21 Oct 2021

New biomarker can help characterize specific types of asthma and COPD

Rutgers researchers have discovered that people with asthma and chronic obstructive pulmonary disease have a protein in their lungs that leaks a small molecule into their bloodstream that restricts their breathing instead of relaxing their airways.

From Rutgers University 21 Oct 2021

Novel technique shows molecule conformations in live cells

Comprehending how proteins twist, bend, and shape-shift, as they work in cells, is vital to gain insights into diseases and normal biology.

21 Oct 2021

'Switching on' Sight using Gene Therapy

AZoLifeSciences speaks to Dr. Raymond Wong about his latest research into eye health and we could potentially 'switch on' sight using gene therapy.

20 Oct 2021

Functional sperm cells can be made in a dish using primate embryonic stem cells, study shows

With global rates of male infertility continuing to rise, a new study in spermatogonial stem cell research led by researchers at the University of Georgia provides hope for future clinical therapies.

From University of Georgia 20 Oct 2021

MIT researchers discover new way to awaken the immune system to attack tumors

Immunotherapy is a promising strategy to treat cancer by stimulating the body's own immune system to destroy tumor cells, but it only works for a handful of cancers. MIT researchers have now discovered a new way to jump-start the immune system to attack tumors, which they hope could allow immunotherapy to be used against more types of cancer.

From Massachusetts Institute of Technology (MIT) 20 Oct 2021

Junk DNA' plays a crucial role in early embryonic development in all mammals, study shows

Nearly half of our DNA has been written off as junk, the discards of evolution: sidelined or broken genes, viruses that got stuck in our genome and were dismembered or silenced, none of it relevant to the human organism or human evolution.

19 Oct 2021

Scientists reveal the importance of circadian rhythm on the immune system

Circadian clocks, which regulate most of the physiological processes of living beings over a rhythm of about 24 hours, are one of the most fundamental biological mechanisms.

19 Oct 2021

High tumor-infiltrating lymphocytes could indicate a better chance of survival in esophageal cancer

Cancerous tumors are made up of many more components than just malignant cells from the tissue of origin. Immune cells can be recruited to the tumor site and form what is known as the tumor microenvironment.

From Osaka University 19 Oct 2021

Metabolic restoration could provide natural protection against HIV

The human immunodeficiency virus (HIV-1) particularly attacks CD4 lymphocytes, a type of white blood cell considered to be the conductor of the immune system.

19 Oct 2021

Study finds novel genes linked to fibromuscular dysplasia using genetic meta-analysis

Recent research identified that three novel genetic variants that control gene expression in the arteries are linked to fibromuscular dysplasia (FMD)—an arterial disease that induces threatening impacts for the heart and vessels.

19 Oct 2021

Experts discover effective means to design and build DNA nanostructures

Researchers recently identified the means to get the best DNA to communicate with membranes in the body.

From The University of New South Wales (UNSW) 19 Oct 2021

Study explains why shift workers are vulnerable to heart problems

Recent research demonstrates how circadian rhythms in heart cells help to change heart function.

19 Oct 2021

Researchers identify the best responding odorant receptors for furaneol

The aroma of caramel is liked by most, but to date, the olfactory receptor that contributes decisively to this sensory impression was not known.

19 Oct 2021

Study identifies highly potent monoclonal antibody against all SARS-CoV-2 variants

Researchers identified a greatly potent monoclonal antibody that aims at the spike protein of SARS-CoV-2.

19 Oct 2021

Novel computationally modeled proteins help control cellular processes

Doctoral assistant Sailan Shui loves to experiment with proteins, activating and deactivating them similar to turning on and off the light switches.

19 Oct 2021

Cellular environment impacts structure of the nuclear pore complex

Context matters. It's true for many facets of life, including the tiny molecular machines that perform vital functions inside our cells.

From Massachusetts Institute of Technology (MIT) 18 Oct 2021

Researchers develop chimeric exosomes that co-activate immune response and tumor microenvironment

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have developed macrophage–tumor chimeric exosomes that co-activate the immune response and tumor microenvironment to support cancer immunotherapy.

18 Oct 2021

Brain immune cells take up large amounts of sugar at the beginning of neurodegenerative disease

At the beginning of neurodegenerative disease, the immune cells of the brain – the "microglia" – take up glucose, a sugar molecule, to a much greater extent than hitherto assumed.

18 Oct 2021

Skin regeneration after an injury may be linked with motility of skin stem cells

Although sometimes hard to accept, with aging, many things in our bodies change. One of these is the ability of the skin to regenerate. Old skin is just not as good as young skin at healing wounds. However, the molecular and cellular mechanisms underlying this are largely unknown.

18 Oct 2021

Cell News and Research

Identification of genetic variant provides a big step for precision medicine in dialysis

New biomarker can help characterize specific types of asthma and COPD

Novel technique shows molecule conformations in live cells

'Switching on' Sight using Gene Therapy

Functional sperm cells can be made in a dish using primate embryonic stem cells, study shows

MIT researchers discover new way to awaken the immune system to attack tumors

Junk DNA' plays a crucial role in early embryonic development in all mammals, study shows

Scientists reveal the importance of circadian rhythm on the immune system

High tumor-infiltrating lymphocytes could indicate a better chance of survival in esophageal cancer

Metabolic restoration could provide natural protection against HIV

Study finds novel genes linked to fibromuscular dysplasia using genetic meta-analysis

Experts discover effective means to design and build DNA nanostructures

Study explains why shift workers are vulnerable to heart problems

Researchers identify the best responding odorant receptors for furaneol

Study identifies highly potent monoclonal antibody against all SARS-CoV-2 variants

Novel computationally modeled proteins help control cellular processes

Cellular environment impacts structure of the nuclear pore complex

Researchers develop chimeric exosomes that co-activate immune response and tumor microenvironment

Brain immune cells take up large amounts of sugar at the beginning of neurodegenerative disease

Skin regeneration after an injury may be linked with motility of skin stem cells

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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