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Latest CRISPR-Cas Gene Editing Can Eliminate All Traces of HIV Virus From Infected Cells

New research presented early ahead of this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024, Barcelona, 27-30 April) from a team of researchers in the Netherlands shows how the latest CRISPR-Cas gene editing technology can be used to eliminate all traces of the HIV virus from infected cells in the laboratory, raising hopes of a cure.

20 Mar 2024

Cells Harvested From Urine May Have Diagnostic Potential for Kidney Disease

Genes expressed in human cells harvested from urine are remarkably similar to those of the kidney itself, suggesting they could be an important non-invasive source of information on the kidney.

20 Mar 2024

Using Genomic Methods to Track Pesticide Resistance

Pesticides are used by farmers to manage agricultural pests. However, pesticide-resistant insects frequently become immune to their toxins.

19 Mar 2024

Soil Bacteria Gene Discovery Offers Hope for Bioremediation Efforts

Some soil bacteria can acquire sets of genes that enable them to pump the heavy metal nickel out of their systems, a study has found.

19 Mar 2024

Students Work with Experts to Create a High-Quality Pear Genome Assembly

Pears are big business in the Pacific Northwest US. But did you know that traditional pear breeding has remained largely unchanged for centuries?

18 Mar 2024

Adhesion GPCR Mayo Plays Key Role in Midgut Development of Fruit Flies

Adhesion GPCRs belong to the large family of G protein-coupled receptors (GPCRs). There are about 700 variants in humans, which are responsible for sensory impressions, hormonal cycles, controlling the cardiovascular system and more.

18 Mar 2024

Transcriptome Profiling Reveals Age-Associated Changes in the Human Brain

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 5, entitled, "Genome-wide transcriptome profiling and development of age prediction models in the human brain."

18 Mar 2024

Study Deciphers Mechanism That Helps Viruses Choose to Turn Nasty or Stay Friendly

Researchers from the Shmunis School of Biomedicine and Cancer Research at Tel Aviv University have deciphered a novel complex decision-making process that helps viruses choose to turn nasty or stay friendly to their bacterial host.

14 Mar 2024

Machine Learning Reveals Cancer-Causing DNA Repeats

It has been difficult to identify and characterize repeats of DNA sequences, also known as “junk DNA” or “dark matter,” that are found in chromosomes and may be involved in cancer or other diseases.

14 Mar 2024

Researchers Unveil Simple Trick to Improve Accuracy Of Plant Genetics Research

Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables – such as temperature – affect gene activity in plants.

14 Mar 2024

Widespread Gene Flow Marks Unique Evolutionary History in Giraffes

Evolutionary biologists and non-experts alike have always held a special place in their minds for giraffes, with their bizarre body plans.

13 Mar 2024

New CRISPR Method Allows Comprehensive Screening of Cancer Mutations

Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways -; some mutations simply replace one DNA nucleotide with another, while others insert or delete larger sections of DNA.

13 Mar 2024

Study Identifies Protein Key to Preserving Neuronal Identity

Epigenetic processes allow different cell types to emerge from a single genome. Throughout development, cells differentiate and acquire distinct characteristics by expressing the same genome in different ways.

13 Mar 2024

AI Research Gives Unprecedented Insight Into Heart Genetics and Structure

A ground-breaking research study has used AI to understand the genetic underpinning of the heart’s left ventricle, using three-dimensional images of the organ.

12 Mar 2024

Multiresolution DNA Simulation in Viral Genome Packaging

Researchers at the University of Illinois Urbana-Champaign stated in the journal Nature that a computational model of the more than 26 million atoms in a DNA-packed viral capsid broadens the knowledge of virus structure and DNA dynamics, discoveries that potentially open up new research directions and therapeutic targets.

7 Mar 2024

The Secrets of Toxic Algal Blooms: A Deep Dive into Prorocentrum cordatum's Cell Biology

Professor Dr Ralf Rabus of the University of Oldenburg has carried out the first comprehensive analyses of the peculiar cell biology of Prorocentrum cordatum, a globally distributed species of the dinoflagellates group.

6 Mar 2024

CSHL Researchers Unravel Why Some Splicing-Based Drugs Tend to Work Better Than Others

Spinal muscular atrophy, or SMA, is the leading genetic cause of infant death. Less than a decade ago, Cold Spring Harbor Laboratory (CSHL) Professor Adrian Krainer showed this brutal disease can be treated by tweaking a process called RNA splicing.

6 Mar 2024

First Whole Genome Sequencing of Male Breast Cancer Reveals Potential Treatment Targets

Male breast cancer has distinct alterations in the tumor genome that may suggest potential treatment targets, according to a study by Weill Cornell Medicine investigators.

5 Mar 2024

'lncREST' RNA Unveiled as Key Player in DNA Replication Stress Response

Researchers at Cima Universidad de Navarra have discovered that a ribonucleic acid that does not contain information to make proteins (long non-coding RNA) plays a crucial role in signalling and repairing errors in DNA replication during cell division.

5 Mar 2024

Researchers Identify Proteins to Reprogram Fibroblasts into Limb Progenitor Cells

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or "reprogram" fibroblasts -; the most commonly found cells in skin and connective tissue -; into cells with similar properties to limb progenitor cells.

5 Mar 2024