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First Humanized Mouse Model for Congenital Adrenal Hyperplasia Developed

Mice with a defected human gene responsible for a rare genetic disease, called congenital adrenal hyperplasia, have been developed for the first time.

16 May 2023

Fecal Microbiota Transplantation to Help in Clostridioides difficile Infection

In Europe, Clostridioides difficile infection results in severe diarrhea and leads to the death of around 20,000 patients, every year. It is one of the most common hospital-acquired infections.

16 May 2023

Infections with the Fungus Candida auris on the Rise in Germany

Candida auris is an extremely new species among yeasts from the Candida genus that cause infections in humans: it was only reported in 2009, and no evidence has been found prior to the 1990s.

16 May 2023

Discovery of Shanghai APP Mutation Offers New Avenues for Treatment of Alzheimer's Disease

Alzheimer's disease (AD) is a progressive neurodegenerative disorder affecting tens of millions of people worldwide, and it is the most common cause of dementia.

15 May 2023

Increase in Certain Bacterial Species Indicates Intestinal Candida Fungi Overgrowth

The bacteria present in the intestine provide information about the quantities of fungi of the potentially disease-causing Candida genus.

15 May 2023

Understanding How Cell-to-Cell Communication Networks Drive Pancreatic Cancer Development

Discussions of cancer often stress the genetic mutations that drive disease by altering the normal function of cellular proteins.

12 May 2023

Patient-Derived Organoids can Help Identify Effective Personalized Cancer Therapies

Researchers created organoids from cancer cells to reduce the need for trial and error in identifying effective cancer treatments in one of many cancer studies scheduled for presentation this week at Digestive Disease Week (DDW) 2023.

9 May 2023

Manipulating Brain Cells via Light Irradiation

An international research team, comprising scientists from DZNE, University Hospital Bonn, the Netherlands, and the US has been awarded a US$ 1.3 million grant by the "Human Frontier Science Program" to investigate brain immune cells and manipulate them via light irradiation.

8 May 2023

Researchers Create a Computational Tool to Gain New Insights From Multi-Omics Data

Despite the astounding advances made in understanding the biologic underpinnings of cancer, many cancers are missing obvious genetic drivers.

5 May 2023

Innate Tumor Suppression Mechanism Uncovered

The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it.

5 May 2023

Immune Evasion Mechanism of TNBC Cells Discovered

Freiburg researchers discover a mechanism by which cancer cells escape the immune system.

5 May 2023

Study Reveals an Immunological Strategy to Overcome Microbiome-Related Immunotherapy Resistance

Cancer immunotherapy has transformed the treatment of many types of cancer. Yet, for reasons that remain poorly understood, not all patients get the same benefit from these powerful therapies.

4 May 2023

Study Reveals That Transcriptional Buffering Occurs in Rett Syndrome Nerve Cells

Every cell in our body is able to turn genes (DNA) on or off, producing RNA, but when genes are 'turned on' to the wrong level it can result in a variety of health conditions.

3 May 2023

New Bio-Inspired Molecules can Enhance Bone Regeneration in Mice

People's ability to regenerate bones declines with age and is further decreased by diseases such as osteoporosis.

2 May 2023

Study Uncovers Somatic Mutations That Play a Role in Common Form of Adult Epilepsy

Epilepsy affects approximately 1-in-26 people and the most common form, known as temporal lobe epilepsy (TLE), often cannot be adequately treated with anti-seizure medications.

2 May 2023

3D Genome Mapping may Lead to Targeted Therapeutic Options for Ependymoma

Researchers led by Sanford Burnham Prebys assistant professor Lukas Chavez, Ph.D., are leveraging the latest technology to take a never-before-seen look at ependymoma, one of the deadliest pediatric brain tumors.

28 Apr 2023

High-Throughput Screening of Existing Drugs to Fight Multiple Myeloma More Effectively

Multiple myeloma is a rare blood cancer caused by the uncontrolled multiplication of abnormal plasma cells.

28 Apr 2023

Novel Genetic Disorder Associated With Neurodevelopmental Differences Discovered

Researchers from Children's Hospital of Philadelphia and Princeton University have discovered a novel genetic disorder associated with neurodevelopmental differences.

27 Apr 2023

A Study on Gene Silencing Through a Recent Trial

Dr Catherine Mummery, a consultant neurologist at UCL Queen Square Institute of Neurology & the National Hospital for Neurology and Neurosurgery, has led a trial. The trial signifies for the first time that a “gene silencing” method has been taken in Alzheimer’s and dementia disease.

From University College London 27 Apr 2023

Capturing Viruses in a Lipid Trap

Viruses like influenza A and Ebola invade human cells in a number of steps. In an interdisciplinary approach, research teams from Heidelberg University and Heidelberg University Hospital investigated the final stages of viral penetration using electron tomography and computer simulations.

26 Apr 2023

Hospital News and Research

First Humanized Mouse Model for Congenital Adrenal Hyperplasia Developed

Fecal Microbiota Transplantation to Help in Clostridioides difficile Infection

Infections with the Fungus Candida auris on the Rise in Germany

Discovery of Shanghai APP Mutation Offers New Avenues for Treatment of Alzheimer's Disease

Increase in Certain Bacterial Species Indicates Intestinal Candida Fungi Overgrowth

Understanding How Cell-to-Cell Communication Networks Drive Pancreatic Cancer Development

Patient-Derived Organoids can Help Identify Effective Personalized Cancer Therapies

Manipulating Brain Cells via Light Irradiation

Researchers Create a Computational Tool to Gain New Insights From Multi-Omics Data

Innate Tumor Suppression Mechanism Uncovered

Immune Evasion Mechanism of TNBC Cells Discovered

Study Reveals an Immunological Strategy to Overcome Microbiome-Related Immunotherapy Resistance

Study Reveals That Transcriptional Buffering Occurs in Rett Syndrome Nerve Cells

New Bio-Inspired Molecules can Enhance Bone Regeneration in Mice

Study Uncovers Somatic Mutations That Play a Role in Common Form of Adult Epilepsy

3D Genome Mapping may Lead to Targeted Therapeutic Options for Ependymoma

High-Throughput Screening of Existing Drugs to Fight Multiple Myeloma More Effectively

Novel Genetic Disorder Associated With Neurodevelopmental Differences Discovered

A Study on Gene Silencing Through a Recent Trial

Capturing Viruses in a Lipid Trap

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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