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The Influence of 'Silent' Mutations on Genetic Disorders

Genetic disorders -; like cystic fibrosis and Huntington's disease -; are considered incurable, with gene mutations occurring in essentially every cell of the body.

29 Aug 2024

Nutrient Deprivation Strategy Kills Breast Cancer Cells by Blocking Adaptive Pathways

Cancer cells have voracious appetites. And there are certain nutrients they can't live without. Scientists have long hoped they might stop tumors in their tracks by cutting off an essential part of cancer cells' diet. But these cells are crafty and often find a new way to get what they need. How? By reprogramming their metabolism and switching to backup food supplies.

29 Aug 2024

New Map Reveals Hidden Interactions Between Receptors and Proteins

A single superfamily of receptors found on the surface of human cells is the target of one out of every three FDA-approved medications.

28 Aug 2024

Stem Cell Research Sheds Light on Rare Pediatric Condition

Scientists have identified mutations in the DENND5A gene that cause severe neurodevelopmental issues in infants, leading to improper brain cell division during development.

28 Aug 2024

Cryo-EM Study Sheds Light on HSV Drug Resistance Mechanisms Through Protein Movement

All organisms -; from fungi to mammals -; have the capacity to evolve and adapt to their environments. But viruses are master shapeshifters with an ability to mutate greater than any other organism. As a result, they can evade treatments or acquire resistance to once-effective antiviral medications.

28 Aug 2024

CDCA7's Role in DNA Methylation Maintenance Revealed in Recent Study

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked. Epigenetic modifications can act as on-off switches to regulate gene expression and help generate diverse cell types without changing the underlying DNA sequence. It is how the body ensures that brain-related genes don't get turned on in heart cells, for example.

28 Aug 2024

Pesticide Exposure Strongly Correlated with Fewer Wild Bee Sightings

Whether you're strolling through a garden, wandering a park, or simply enjoying an open space in the United States, you're likely to notice bees buzzing about the flowers. While honeybees, imported from Europe in the 17th century to produce honey, are the most recognizable, they aren't the only bees at work. If you're a keen observer, you might spot some of the thousands of less familiar, native bee species that call these spaces home.

28 Aug 2024

EMBL Researchers Develop Novel Photoacoustic Probes to Monitor Brain Activity

To understand the brain better, we need new methods to observe its activity.

28 Aug 2024

High-Resolution Structures Illuminate the Chloroplast Protein Import Machinery in Plants

Two groundbreaking studies published in the journal Cell shed light on the assembly, function and evolutionary diversity of the chloroplast protein import system.

28 Aug 2024

NIR Spectroscopy Offers a New Frontier in Crop Analysis

In the agricultural and food industry, determining the chemical composition of raw materials is important for production efficiency, application, and price. Traditional laboratory testing is time-consuming, complicated, and expensive. New research from the University of Illinois Urbana-Champaign demonstrates that near-infrared (NIR) spectroscopy and machine learning can provide quick, accurate, and cost-effective product analysis.

28 Aug 2024

Unraveling the Molecular Mechanism Behind Neocapritermes taracua's Explosive Defense

Researchers from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, in cooperation with colleagues from the Faculty of Tropical AgriScience of the Czech University of Life Sciences in Prague, are unraveling the mysteries of the life of termites.

28 Aug 2024

A Breakthrough in RNA Therapy for Heart and Nervous System Diseases

Researchers at the University of California San Diego have developed new techniques to sculpt RNA molecules into circles that may result in more potent and long-lasting treatments.

27 Aug 2024

Innovative Stem Cell Research Unveils Glial Cell Dynamics in Multiple Sclerosis

Researchers from The New York Stem Cell Foundation (NYSCF) Research Institute and Case Western Reserve University have discovered novel ways in which glia, by using the largest known collection of stem cell models from MS patients, essential brain support cells contribute to the disease.

27 Aug 2024

New Screening Methods Uncover Antivirulence Compounds from Arctic Actinobacteria

Antibiotics are the linchpin of modern medicine: without them, anyone with open wounds or needing to undergo surgery would be at constant risk of dangerous infections.

27 Aug 2024

New HiQuad Neo Mass Spectrometer Delivers Advanced Performance and Flexibility

With its new HiQuad Neo mass spectrometer, Pfeiffer Vacuum combines powerful performance with flexibility and user-friendly operation.

27 Aug 2024

Nile Grass Rats Become New Model for CRISPR Genome Editing

A team of researchers at Michigan State University has discovered a set of methods that enabled the first successful CRISPR-based genome editing in Nile grass rats.

27 Aug 2024

Rare CCDC201 Genotype Significantly Affects Menopause Onset in Women

Scientists at deCODE genetics and collaborators, have identified a sequence variant in the CCDC201 gene that when inherited from both parents homozygous causes menopause on average nine years earlier.

27 Aug 2024

Insights into Hmmr's Role in Cognitive Decline and Lifespan

The authors investigate the physiological functions of Terc-53 by creating transgenic mice that overexpress this noncoding RNA. They observe that Terc-53 overexpression affects normal aging in mammals, contributing to cognitive decline and shortened lifespan.

27 Aug 2024

Computational Modeling and Experimental Findings on Nucleosome Constraining in Mitosis

Individual cells divide through a process called mitosis, during which the cell's copied DNA is separated between two resulting daughter cells. Despite recent advances in cell biology, the mechanism by which DNA condenses during mitosis is still poorly understood. Researchers recently tracked small stretches of DNA wound around histone proteins, called nucleosomes, to better characterize nucleosome behavior during cell division.

27 Aug 2024

Engineering Purple Bacteria for Enhanced Bioplastic Synthesis

In a world overrun by petroleum-based plastics, scientists are searching for alternatives that are more sustainable, more biodegradable and far less toxic to the environment.

27 Aug 2024

Research News and Research

The Influence of 'Silent' Mutations on Genetic Disorders

Nutrient Deprivation Strategy Kills Breast Cancer Cells by Blocking Adaptive Pathways

New Map Reveals Hidden Interactions Between Receptors and Proteins

Stem Cell Research Sheds Light on Rare Pediatric Condition

Cryo-EM Study Sheds Light on HSV Drug Resistance Mechanisms Through Protein Movement

CDCA7's Role in DNA Methylation Maintenance Revealed in Recent Study

Pesticide Exposure Strongly Correlated with Fewer Wild Bee Sightings

EMBL Researchers Develop Novel Photoacoustic Probes to Monitor Brain Activity

High-Resolution Structures Illuminate the Chloroplast Protein Import Machinery in Plants

NIR Spectroscopy Offers a New Frontier in Crop Analysis

Unraveling the Molecular Mechanism Behind Neocapritermes taracua's Explosive Defense

A Breakthrough in RNA Therapy for Heart and Nervous System Diseases

Innovative Stem Cell Research Unveils Glial Cell Dynamics in Multiple Sclerosis

New Screening Methods Uncover Antivirulence Compounds from Arctic Actinobacteria

New HiQuad Neo Mass Spectrometer Delivers Advanced Performance and Flexibility

Nile Grass Rats Become New Model for CRISPR Genome Editing

Rare CCDC201 Genotype Significantly Affects Menopause Onset in Women

Insights into Hmmr's Role in Cognitive Decline and Lifespan

Computational Modeling and Experimental Findings on Nucleosome Constraining in Mitosis

Engineering Purple Bacteria for Enhanced Bioplastic Synthesis

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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