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Cellular recycling system of autophagy likely to help in wound repair

In the fruit fly Drosophila, a team led by Maria Leptin discovered that autophagy, a stress response process in cells, plays a significant role in wound repair.

14 Mar 2022

New tools for measuring the biological ages of various organ systems

It's common to say that someone looks either younger or older than their chronological age, but aging is more than skin deep.

9 Mar 2022

Study takes a deep dive into the molecular biology of the brain in bipolar disorder patients

In a comprehensive study involving one of the largest-ever samples of post-mortem brains, scientists at the Lieber Institute for Brain Development, in collaboration with researchers at the Johns Hopkins School of Medicine and Bloomberg School of Public Health, have pinpointed significant differences in gene expression in two specific regions of the brains of hundreds of patients who had bipolar disorder.

8 Mar 2022

T cells sometimes remain in the skin for years, research finds

Human immune cells not only circulate in the blood, but can also occupy certain tissues and sometimes remain there for years.

8 Mar 2022

Researchers observe cellular rejuvenation therapy securely promoting reverse aging in mice

Researchers at Salk observed no rise in cancer or other health problems in mice treated with an anti-aging regimen at the beginning of their middle age.

8 Mar 2022

Research develops novel ways to recreate totipotency by cellular reprogramming

Adult cells in our bodies can only produce cells of the same type. A skin cell, for example, can only produce skin cells and not muscle cells. This restricts the therapeutic potential of mature cells.

8 Mar 2022

Researchers discover unusual exploitation of the human immune system by fungus Candida albicans

During infection, the yeast Candida albicans stimulates the release of tiny RNA fragments, which then stimulate its own growth.

3 Mar 2022

Study uncovers genomic drivers and therapeutic vulnerabilities of transformed cutaneous T-cell lymphoma

Cutaneous T-cell lymphoma (CTCL) is an incurable, rare cancer of skin-homing T cells that is highly disfiguring and lethal at advanced stages.

2 Mar 2022

Novel molecular pathway shared by ALS and frontotemporal dementia identified

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

1 Mar 2022

Microbes hindering cancer therapy seem to play a bigger role than helpful ones

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

1 Mar 2022

TGen collaborates with Deepcell to employ AI for analyzing single cell morphology

The Translational Genomics Research Institute, an affiliate of City of Hope, is partnering with a Silicon Valley firm to become one of the first research institutes in the world to employ a new Artificial Intelligence-powered imaging and sorting technology to classify and isolate individual diseased cells.

23 Feb 2022

Researchers elucidate how early embryo cells begin to independently produce proteins

It happens in the first hours after fertilization: The cells of the early embryo begin to independently produce proteins, the building blocks for cells and organs.

16 Feb 2022

Cancer driving protein plays crucial role in the development of lung cancer, study reveals

Lung cancer is the second leading cancer in the United States and the No. 1 cause of cancer-associated deaths.

15 Feb 2022

Experts identify the master regulator of Nodal signaling in human embryonic stem cells

A new study has led to the discovery that the Hippo signaling effector YAP1 is a master controller of Nodal signaling in hESCs for a process crucial to human development.

14 Feb 2022

Intracellular pathogens trick the host’s immune system to evade destruction

A signaling mechanism that enables bacteria like Salmonella to escape destruction by the immune system of the host was discovered by scientists.

From The University of California, Davis 14 Feb 2022

Pro-regenerative metabolite supports elevated tissue regeneration and delays aging, study reveals

Research recognizes uridine as a pro-regenerative metabolite that highlighted human stem cell activity and improved restructuring and tissue repair.

14 Feb 2022

P53 protein induces leader cell behavior, migration and clearance during epithelial tissue repair

New research led by the University of Bristol has found the protein p53 plays a key role in epithelial migration and tissue repair.

11 Feb 2022

Researchers decipher the genome of Steller’s sea cow from fossil bones

During the Ice Age, giant mammals such as mammoths, sabre-toothed cats and woolly rhinoceroses once roamed Northern Europe and America.

9 Feb 2022

Kras oncogenes use genetic reprogramming to drive tumorigenesis

Cancerous tumors are made up of rapidly growing, abnormally shaped, cells that can infiltrate and destroy healthy tissues, travel to other parts of the body, and form additional tumors.

8 Feb 2022

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

An international team led by the Case Western Reserve University School of Medicine has discovered novel properties of the protein Gasdermin B that promotes repair of cells lining the gastrointestinal tract in people with chronic inflammatory disorders like Crohn's disease and ulcerative colitis.

8 Feb 2022

Skin News and Research

Cellular recycling system of autophagy likely to help in wound repair

New tools for measuring the biological ages of various organ systems

Study takes a deep dive into the molecular biology of the brain in bipolar disorder patients

T cells sometimes remain in the skin for years, research finds

Researchers observe cellular rejuvenation therapy securely promoting reverse aging in mice

Research develops novel ways to recreate totipotency by cellular reprogramming

Researchers discover unusual exploitation of the human immune system by fungus Candida albicans

Study uncovers genomic drivers and therapeutic vulnerabilities of transformed cutaneous T-cell lymphoma

Novel molecular pathway shared by ALS and frontotemporal dementia identified

Microbes hindering cancer therapy seem to play a bigger role than helpful ones

TGen collaborates with Deepcell to employ AI for analyzing single cell morphology

Researchers elucidate how early embryo cells begin to independently produce proteins

Cancer driving protein plays crucial role in the development of lung cancer, study reveals

Experts identify the master regulator of Nodal signaling in human embryonic stem cells

Intracellular pathogens trick the host’s immune system to evade destruction

Pro-regenerative metabolite supports elevated tissue regeneration and delays aging, study reveals

P53 protein induces leader cell behavior, migration and clearance during epithelial tissue repair

Researchers decipher the genome of Steller’s sea cow from fossil bones

Kras oncogenes use genetic reprogramming to drive tumorigenesis

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

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