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Scientists Discover Specific Genes Involved in Rare, Life-Threatening Heart Disease

By identifying genes in patients and testing their effects in fruit flies, researchers from Sanford Burnham Prebys have found new genes that contribute to hypoplastic left heart syndrome (HLHS), a rare, life-threatening heart disease that occurs in infants.

18 Jul 2023

Extrusion-Mediated Self-Renewal: A New Way for Kidney Cells to Stay Healthy

University of Texas at Dallas scientists have discovered a previously unknown "housekeeping" process in kidney cells that ejects unwanted content, resulting in cells that rejuvenate themselves and remain functioning and healthy.

14 Jul 2023

New P38 Inhibitors Selectively Target Cardiac Cell Death

The p38 protein regulates a wide variety of cellular functions and is related to diseases such as chronic inflammation, immunological disorders, or cancer.

14 Jul 2023

The Future of Nanobiotechnology: Ethical Considerations

Prosthetics moved by thoughts. Targeted treatments for aggressive brain cancer. Soldiers with enhanced vision or bionic ears.

13 Jul 2023

Glucose-Sensing Neurons May Play a Role in Regulating Blood Sugar

The body's blood glucose level needs to be maintained in a relatively narrow range. It cannot be too high, as it can lead to diabetes, and it cannot be too low because it can cause fainting or even death.

12 Jul 2023

Revolutionizing Drug Design with Light-Activated Molecular Machines

Cells “talk” to one another to coordinate crucial biological activities such as immune activation, muscle contraction, hormone release, neuronal firing, and digestion using calcium signaling as a primary mechanism.

11 Jul 2023

Research may Offer a New Way to Break Through Cancer's Hypoxia-Induced Defenses

For most of our tissues and cells, a lack of oxygen, or hypoxia, is bad news. Cancer cells, on the other hand, can thrive in these hypoxic conditions, which render tumors less susceptible to anti-cancer treatments, including radiation.

11 Jul 2023

New Culture System may Improve Efficiency and Safety of Genome Editing in HSCs

Hematopoietic stem cells (HSCs) are rare cells found in the bone marrow that produce red blood cells, white blood cells, and platelets.

11 Jul 2023

Unknown Membrane Proteins for Ovarian Cancer Diagnosis

Three previously undiscovered membrane proteins in ovarian cancer have been discovered by a study led by Nagoya University in Japan.

10 Jul 2023

T cells are Sensitive to Genetic Disturbances Within Mitochondrial Power Plants

All cells have their own power plants, called mitochondria. There are often more than 100 mitochondria per cell and each possesses their own genome, which in turn contains genes responsible for energy production.

7 Jul 2023

Study Reveals Key Insights Into the Evolution of Tumor Microenvironment in Gastric Cancer

A new study led by researchers at The University of Texas MD Anderson Cancer Center provides a deeper understanding of the evolution of the tumor microenvironment during gastric cancer progression.

7 Jul 2023

Glutaminase 2 Plays a Key Role in Glucose Homeostasis

Glutaminase 2 (GLS2) is a master regulator of glutaminolysis. GLS2 converts glutamine to glutamate, thereby playing a role in cellular energy production. GLS2 is abundant in the liver, and is also found in pancreatic β-cells. However, the role of GLS2 in pancreatic islets – in which both ɑ- and β- cells are present – associated with glucose metabolism is currently unknown.

6 Jul 2023

Understanding How Malaria Parasite Modulates Apicoplast Gene Expression

A recent study supported by Tokyo Tech’s World Research Hub Initiative discovered that gene expression within the apicoplast, an organelle in the malaria parasite Plasmodium falciparum, is controlled by melatonin (the circadian signaling hormone) in host blood and intrinsic parasite cues via a factor called ApSigma.

5 Jul 2023

Extraoral Bitter Taste Receptors Serve as Endogenous Sensors for Bile Acids

Taste receptors for bitter substances are not only observed on the tongue but also on cells outside of the oral cavity.

5 Jul 2023

Genetically Modified iPS Cell Applications for Fabry Disease

iPS cells have had a significant impact on biology and medicine, and they are expected to increase regenerative medicine. Clinical trials with various cell types derived from iPS cells have been performed since 2014 when a sheet of retinal pigment epithelial cells obtained from iPS cells was transplanted into patients with age-related macular degeneration.

4 Jul 2023

Ancient Virus-Like Transposons Found to Mediate Horizontal Gene Transfer in Worms

Scientists have known for decades that genes can be transferred from one species to another, both in animals and plants.

30 Jun 2023

Water Fasting Offers Short-Term Weight Loss, But No Long-Term Benefits

Water fasts -; where people consume nothing but water for several days -; might help you lose weight, but it's unclear how long you'll keep it off, according to research from the University of Illinois Chicago.

30 Jun 2023

Understanding Mammary Biology That May Help Find Therapeutic Targets for Breast Cancer

A new study led by researchers at The University of Texas MD Anderson Cancer, University of California, Irvine and Baylor College of Medicine has created the world's largest and most comprehensive map of normal breast tissue, providing an unprecedented understanding of mammary biology that may help identify therapeutic targets for diseases such as breast cancer.

29 Jun 2023

Cell Fate Conversion Plays Crucial Role in Cancer Research

Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin and the Centre for Genomic Regulation (CRG) in Barcelona have discovered how cells speed changes to their identity known as “cell fate conversion.”

28 Jun 2023

Immune Deficits in Space are Temporary

An increase in proof has been found that astronauts are highly vulnerable to infections while in space. For instance, astronauts on board the International Space Station (ISS) generally suffer from skin rashes, and also respiratory and non-respiratory diseases.

23 Jun 2023