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Rare inherited mutation in TP53 gene predisposes to a wide range of cancers

Rare inherited mutations in the body's master regulator of the DNA repair system – the TP53 gene – can leave people at a higher risk of developing multiple types of cancer over the course of their lives.

17 Jul 2020

New, promising CAR T cell therapy results in exceptional patient recovery

In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of cancerthe cells.

16 Jul 2020

New study can help treat metabolic and genetic bone diseases

A team of researchers, headed by Kanazawa University, has demonstrated that a tiny fish can potentially stop painful genetic and metabolic bone diseases. The study was recently published in the Communications Biology journal.

15 Jul 2020

Umbilical cord blood treats children born with non-cancerous genetic disorders

Researchers at UPMC Children's Hospital of Pittsburgh found that infusing umbilical cord blood -- a readily available source of stem cells -- safely and effectively treated 44 children born with various non-cancerous genetic disorders, including sickle cell, thalassemia, Hunter syndrome, Krabbe disease, metachromatic leukodystrophy (MLD) and an array of immune deficiencies.

15 Jul 2020

PET radiotracer is safe and effective for imaging malignant brain tumors

A first-in-human study presented at the Society of Nuclear Medicine and Molecular Imaging 2020 Annual Meeting has demonstrated the safety, favorable pharmacokinetic and dosimetry profile of 64Cu-EBRGD, a new, relatively long-lived PET tracer, in patients with glioblastomas.

14 Jul 2020

Researchers develop bioink to print tissue-mimicking material in 3D printers

A research group led by Daniel Aili, associate professor at Linköping University, has developed a bioink to print tissue-mimicking material in 3D printers.

14 Jul 2020

UTMB researchers uncover new mechanism for designing dengue therapeutics

A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered a new mechanism for designing antiviral drugs for dengue virus. The study is currently available in Proceedings of the National Academy of Sciences.

14 Jul 2020

Functional bone imaging technique reveals the progression of knee osteoarthritis

A new approach to functional bone imaging has established that bone metabolism is abnormally elevated in patients with knee osteoarthritis.

14 Jul 2020

uEXPLORER TB-PET/CT scanner captures complete picture of systemic inflammatory arthritis

For the first time, physicians can examine the systemic burden of inflammatory arthritis simultaneously across all joints and organ systems, using the high-sensitivity, high-resolution uEXPLORER total-body positron emission tomography/computed tomography (TB-PET/CT) scanner.

14 Jul 2020

Total-body dynamic PET scans can produce high-quality images of metastatic cancer

Results from the first study using uEXPLORER to conduct total-body dynamic positron emission tomography (PET) scans in cancer patients show that it can be used to generate high-quality images of metastatic cancer.

14 Jul 2020

Study confirms the efficacy of PSMA PET/CT in detection and management of recurrent prostate cancer

New research confirms the high impact of PSMA PET/CT in the detection and management of recurrent disease in prostate cancer patients.

14 Jul 2020

Study reveals the key role of adiponectin in muscle regeneration

Mesenchymal stem cells, or MSCs, have the ability to differentiate into an array of different types of cells, such as fat, bone, and muscle cells.

From Osaka University 13 Jul 2020

New drug enables the immune system to attack ovarian cancer, TGen study shows

A drug known as SP-2577 could help enable the body's own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

13 Jul 2020

Study highlights the role of hematopoietic immune cells in gene regulation

More often, the human body is viewed as a “machine” containing specialized components: immune cells protect against pathogens, organs contribute physiological functions, and soft tissue and bones give structure.

6 Jul 2020

Mineral-coated microparticles are better vehicles for promising mRNA-based therapy

University of Wisconsin-Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination -- including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans.

3 Jul 2020

Importance of Sustainable Food

AZoLifeSciences speaks to Iñigo Charola about the importance of sustainable food production, and how the development of cultured meat can help.

From Biotech Foods 3 Jul 2020

Developments in Engineered T Cells for Type 1 Diabetes

AZoLifeSciences speaks to Professor David J. Rawlings from the Seattle children's hospital about recent developments in engineered T cells for type 1 diabetes.

23 Jun 2020

Study shows MMR vaccine may protect against COVID-19 symptoms

According to a group of experts, the administration of the MMR vaccine could act as a preventive measure to reduce inflammation linked to COVID-19 infection.

22 Jun 2020

New system of gene editing allows for targeted, super-fast DNA repair

In a series of experiments using human cancer cell lines, scientists at Johns Hopkins Medicine say they have successfully used light as a trigger to make precise cuts in genomic material rapidly, using a molecular scalpel known as CRISPR, and observe how specialized cell proteins repair the exact spot where the gene was cut.

18 Jun 2020

New X-ray technique reveals inner architecture of human bones

An international research team has used new X-ray techniques to describe how the architecture of healthy human bones is built up. The team has uncovered a hitherto unknown structure in healthy bones.

16 Jun 2020