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Unraveling Lenacapavir's Impact on the HIV Life Cycle

A new anti-retroviral medication for the treatment of human immunodeficiency virus (HIV) infections was licensed by the US Food and Drug Administration and the European Union just over a year ago.

14 Feb 2024

Hi-C Sequencing Unveils Phage-Host Dynamics in Soil Ecosystems

Bacteriophages-;viruses that infect bacteria-;are common in soil ecosystems.

14 Feb 2024

Unleashing the Potential of CRISPR-COPIES

The last ten years have seen tremendous advancements in CRISPR/Cas systems. These precise genome editing tools can be used for more than just gene therapy and transgenic crop development.

13 Feb 2024

Unlocking RNA Secrets: New Method Exposes Gene Expression's Hidden Hurdles

A new study demonstrates that a method may identify, for the first time, the frequency and precise location of a molecular occurrence known as "backtracking" across the genetic material (genome) of any species.

12 Feb 2024

GWAS Identifies Key Genetic Factors for Lassa Fever Susceptibility and Severity

While combing through the human genome in 2007, computational geneticist Pardis Sabeti made a discovery that would transform her research career.

9 Feb 2024

Scientists Predict DNA Mutations Causing Extra Fingers, Hearts

Our genomes provide the instructions for proper growth and development. Millions of genomic switches, known as enhancers, control the location and timing of gene expression, which in turn ensures the correct proteins are made in the right cells at the right time throughout our lives.

7 Feb 2024

Study Suggests a Link Between DNA Methylation Disorder and Epigenetic Clocks

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation."

7 Feb 2024

Outsmarting Viruses: Scientists Rewire Bacteria for Biomanufacturing Revolution

Genome engineering allows scientists to modify the genetic code of microbes. Now, researchers have engineered the genome of the bacterium Escherichia coli (E. coli) to make it immune to viral infections.

6 Feb 2024

Fruit Flies Shed Light on Evolution Driven by Sexual Selection

Despite their small size, fruit flies have contributed much to the understanding of the genetic foundation of the fast evolution of male external genitalia through sexual selection

5 Feb 2024

New Model Predicts How Soil Microbes Impact Climate

Climate models are essential to predicting and addressing climate change, but can fail to adequately represent soil microbes, a critical player in ecosystem soil carbon sequestration that affects the global carbon cycle.

5 Feb 2024

Decoding Virus-Host Tug-of-War with RNA-Protein Interaction Mapping

The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host.

2 Feb 2024

Study Unveils Dual Role of 7-DHC in Ferroptosis and Cancer Cell Survival

Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, acute kidney injury and inflammation.

2 Feb 2024

Enhanc3D Genomics Appoints Dr Daniel Turner as Chief Scientific Officer

Enhanc3D Genomics, a company developing disruptive technologies to unlock the 3D spatial genome for target and biomarker discovery, today announced the appointment of Dr Daniel Turner as Chief Scientific Officer (CSO). Dan’s deep expertise in genomics technology development and commercialisation will be key to achieving the next phase of Enhanc3D Genomics’ growth.

1 Feb 2024

51 Vertebrate Genomes Sequenced Rapidly, Offering a New Perspective on Human Evolutionary History

The mapping of genetic blueprints for 51 species, such as sharks, turtles, kangaroos, cats, penguins, and dolphins, has advanced the knowledge of evolution and the relationships between animals and people.

30 Jan 2024

SYCE2 Gene Variant Disrupts Alignment of Chromosomes, Potentially Leading to Pregnancy Loss

Scientists at deCODE genetics, a subsidiary of Amgen and their collaborators from Iceland, Denmark and USA published a study today in Nature Structural and Molecular Biology titled "Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effects on recombination".

30 Jan 2024

Bio-Techne’s Advanced Cell Diagnostics (ACD) Sets New Standard in Spatial Biology with Protease-Free RNAscope Multiomics

Bio-Techne Corporation today announced that Advanced Cell Diagnostics (ACD), a Bio-Techne spatial biology brand, has set a new standard with the development of a next-generation, protease-free RNAscope spatial multiomics workflow.

From Bio-Techne 30 Jan 2024

“Free-from-Tree” Production of Vaccine Component QS-21

For the first time, a valuable chemical extracted from the soapbark tree and utilized as a major component in vaccinations has been duplicated in a different plant host, providing the vaccine industry with hitherto unheard-of potential.

29 Jan 2024

Promoter Mutations and Their Association with Autism Risk

The RIKEN Center for Brain Science (CBS) employed genome mutation analysis to investigate the genetics of autism spectrum disorder (ASD) in people and their families. They found that the way a certain type of genetic mutation contributes to the illness differs from that of ordinary mutations.

29 Jan 2024

Scientists Reveal HIV's Secret Weapon for Invading Cell Nucleus

Around one million individuals worldwide become infected with HIV, the virus that causes AIDS, each year.

27 Jan 2024

Lunaphore and Acd Revolutionize Spatial Biology Research With the Launch of the First Fully Automated, Same-Section, Hyperplex Multiomics Application

Bio-Techne Corporation (NASDAQ: TECH) today announced that its spatial biology brands, Lunaphore and Advanced Cell Diagnostics (ACD), will launch the first fully automated spatial multiomics workflow with same-section hyperplex detection of RNA and protein biomarkers.

From Bio-Techne 25 Jan 2024