Diagnostics News and Research

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Scientists Develop AI-Powered Tool to Optimize Gene Delivery

Scientists Develop AI-Powered Tool to Optimize Gene Delivery

Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of the most commonly used gene-delivery vehicles, adeno-associated viruses (AAV), are often slow and inefficient.

9 Aug 2024

Highly Reactive RNA Building Blocks for Enhanced Chip Production

Highly Reactive RNA Building Blocks for Enhanced Chip Production

A multinational research team under the direction of the University of Vienna has been successful in creating new RNA building blocks that exhibit increased photosensitivity and chemical reactivity. In biotechnological and medical research, RNA chips can be produced much faster as a result of this.

1 Aug 2024

New CRISPR-Based Test Achieves Rapid Detection of Tuberculosis

New CRISPR-Based Test Achieves Rapid Detection of Tuberculosis

The rapid detection of Mycobacterium tuberculosis, the etiological agent of tuberculosis.

1 Aug 2024

Rapid Parkinson's Model Opens Door to Personalized Treatments

Rapid Parkinson's Model Opens Door to Personalized Treatments

Scientists at Brigham and Women’s Hospital, a key member of the Mass General Brigham healthcare system, have created a model that swiftly transforms stem cells into brain cells exhibiting protein structures associated with Parkinson’s disease (PD).

30 Jul 2024

Innovative Model Creates Personalized Parkinson's Disease Brain Cells for Drug Testing

Innovative Model Creates Personalized Parkinson's Disease Brain Cells for Drug Testing

A new model developed by Brigham researchers rapidly converts stem cells to brain cells characteristic of Parkinson’s disease to create personalized stem cell models with opportunities to test treatments

29 Jul 2024

Machine Learning and Infrared Light Unlock Health Insights

Machine Learning and Infrared Light Unlock Health Insights

Researchers at Ludwig-Maximilians-Universität München (LMU) and the Max Planck Institute of Quantum Optics (MPQ), in collaboration with Helmholtz Zentrum München, are pioneering a new approach to health screening.

22 Jul 2024

PUMA: A Breakthrough in CRISPR-Cas12 for RNA Biomarker Detection

PUMA: A Breakthrough in CRISPR-Cas12 for RNA Biomarker Detection

CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics.

17 Jul 2024

Surface Plasmon Resonance Sensors: Transforming Drug Development and Clinical Diagnostics

Surface Plasmon Resonance Sensors: Transforming Drug Development and Clinical Diagnostics

The latest developments in SPR-based biosensors and their applications in drug discovery.

15 Jul 2024

Enhancing Precision and Versatility in Genetic Sensor Design

Enhancing Precision and Versatility in Genetic Sensor Design

Genetic sensors play a crucial role within organisms by regulating gene expression in response to environmental stimuli.

2 Jul 2024

Mapping Gene Targets of HNF4A and HNF1A in Human Pancreatic Beta Cells and Liver Cells

Mapping Gene Targets of HNF4A and HNF1A in Human Pancreatic Beta Cells and Liver Cells

Scientists have generated a comprehensive map of the gene targets regulated by the transcription factors HNF4A and HNF1A in human pancreatic beta cells and liver cells.

26 Jun 2024

New Cold-Sensing Protein Discovery Could Revolutionize Pain Management

New Cold-Sensing Protein Discovery Could Revolutionize Pain Management

The only available treatments for millions of people with chronic pain worldwide frequently involve the use of opioids, which pose the risk of addiction and overdose.

24 Jun 2024

Ancestry Bias can Cause CRISPR Screens to Miss Cancer Dependencies

Ancestry Bias can Cause CRISPR Screens to Miss Cancer Dependencies

CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow.

17 Jun 2024

New Method Offers Rapid and Accurate Blood Infection Detection

New Method Offers Rapid and Accurate Blood Infection Detection

Researchers have shown that a novel method could identify bloodstream infections precisely and swiftly. The study findings were presented at ASM Microbe, the annual meeting of the American Society for Microbiology.

17 Jun 2024

Whole Genome Sequencing Provides Answers Where Exome Sequencing Falls Short

Whole Genome Sequencing Provides Answers Where Exome Sequencing Falls Short

Genetic mutations in human DNA can prevent proteins that perform important functions in the body from being formed correctly.

11 Jun 2024

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Advancements in Direct MS with Plasmion’s SICRIT®.

From Plasmion 11 Jun 2024

AMPLON Simplifies DNA Amplification for Diverse Medical Applications

AMPLON Simplifies DNA Amplification for Diverse Medical Applications

A team of researchers from Case Western Reserve University School of Medicine has created a novel method for target DNA sequence amplification, testing, and analysis.

6 Jun 2024

Graph Neural Networks: A Novel Approach to Deciphering Gene-Enhancer Interactions

Graph Neural Networks: A Novel Approach to Deciphering Gene-Enhancer Interactions

Scientists at La Jolla Institute for Immunology (LJI) have developed a new computational method for linking molecular marks on our DNA to gene activity.

4 Jun 2024

"Cervix-on-a-Chip" Offers Promise for New Bacterial Vaginosis Treatments

"Cervix-on-a-Chip" Offers Promise for New Bacterial Vaginosis Treatments

Bacterial Vaginosis (BV) has been identified as one of the many unmet needs in women's health and affects more than 25% of reproductive-aged women.

3 Jun 2024

Protein Imbalance Linked to Rare Developmental Disorder

Protein Imbalance Linked to Rare Developmental Disorder

According to a recent study from the University of Lausanne, serious intellectual impairments can result from both an excess or a shortage of a single protein.

31 May 2024

Genetic Analysis Sheds Light on the Role of Ribosomal DNA Copy Number in Inflammation and Disease

Genetic Analysis Sheds Light on the Role of Ribosomal DNA Copy Number in Inflammation and Disease

Ribosomal DNA (rDNA) is present in hundreds of copies in the genome, but has not previously been part of genetic analyses.

16 May 2024

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