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Breakthrough Discovery on How TGF-Beta Communicates in Cells

Scientists discover how TGF-Beta, a crucial protein in development and cancer, sends its message even while tethered to the cell membrane.

17 Sep 2024

Innovative Approach Supercharges T Cells by Transferring Healthy Mitochondria

Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell exhaustion.

16 Sep 2024

Insights into Peptide Clumping Could Transform Drug Design and Material Science

Scientists from China have investigated how short peptide chains aggregate together in order to deepen our understanding of the process, which is crucial for drug stability and material development.

4 Sep 2024

New Insights into Python Cardiac Biology Could Inform Human Heart Disease Research

Study of python cardiac responses to feeding uncovers structural and epigenetic changes, enhancing understanding of heart disease and therapeutic applications.

2 Sep 2024

Bacterial Protein Utilizes DNA for Target Recognition and Plasmid Elimination

Scientists who have described in a new study the step-by-step details of a bacterial defense strategy see the mechanism as a promising platform for development of a new genome-editing method.

30 Aug 2024

High-Speed Atomic Force Microscopy Reveals Cofilin Binding Patterns in Actin Filaments

Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin.

29 Aug 2024

Cryo-EM Study Sheds Light on HSV Drug Resistance Mechanisms Through Protein Movement

All organisms -; from fungi to mammals -; have the capacity to evolve and adapt to their environments. But viruses are master shapeshifters with an ability to mutate greater than any other organism. As a result, they can evade treatments or acquire resistance to once-effective antiviral medications.

28 Aug 2024

High-Resolution Structures Illuminate the Chloroplast Protein Import Machinery in Plants

Two groundbreaking studies published in the journal Cell shed light on the assembly, function and evolutionary diversity of the chloroplast protein import system.

28 Aug 2024

Cryo-EM Reveals CDCA7's Hemimethylation Sensing in Nucleosome Core Particles

DNA methylation, a process by which methyl groups are added to DNA molecules, is essential for the maintenance of DNA and the overall health of an organism. Disruptions in the standard DNA methylation patterns can lead to immunodeficiency and diseases such as cancer.

27 Aug 2024

Understanding the Molecular Basis of Avian Influenza Host Shift

A recent study by the Cusack group clarifies how a crucial enzyme of the avian influenza virus can change, enabling the virus to spread to mammals.

20 Aug 2024

Mast Cells Recruit Neutrophils in Immune Response

Mast cells are well-known for their part in allergic reactions, but the immune system relies heavily on them. They release chemicals in response to allergens, which cause common allergy symptoms like tissue swelling and inflammation.

5 Aug 2024

Shared Mechanisms in Human and Yeast DNA Replication Revealed

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science and Proceedings of the National Academy of Sciences.

5 Aug 2024

Innovative Nanosensing Method Promises Safer Gene Therapy with Improved AAV Vector Quality

Over the past few decades, there has been remarkable progress in genetic manipulation technologies, bringing us closer to the point where genes can be modified in vivo.

2 Aug 2024

Novel Microscopy Method Revolutionizes Imaging with Reduced Radiation and Faster Results

An international team of scientists, led by Trinity College Dublin, has devised an innovative imaging method using state-of-the-art microscopes that significantly reduces the time and radiation required.

1 Aug 2024

Breakthrough in Understanding Brain's Master Protein

Proteins engage in intricate molecular movements to fulfill their biological roles. The NMDAR protein, crucial for brain function, performs a particularly complex dance.

1 Aug 2024

Cryo-EM Reveals Structural Differences in Fetal and Adult Muscle Receptors

The connections between the nervous system and muscles develop differently across the kingdom of life. It takes newborn humans roughly a year to develop the proper muscular systems that support the ability to walk, while cows can walk mere minutes after birth and run not long after.

1 Aug 2024

Harvard Researchers Crack the Code on Western Equine Encephalitis Decline

The story of the rise and fall of western equine encephalitis as a lethal disease offers essential lessons about how a pathogen can gain or lose its ability to jump from animals to humans.

29 Jul 2024

Probing Plasma Membrane Dynamics with Cryo-Electron Microscopy

Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood.

25 Jul 2024

High Performance SEM Helps Drive NZ Towards a Smart, Green Future

The existing electron microscopy capabilities have been improved with the installation of a TESCAN CLARA Scanning Electron Microscope (SEM).

24 Jul 2024

Flu Virus Exploits Immune System Weakness to Infect Cells

The majority of influenza viruses enter animal or human cells through particular surface-based pathways. It has recently been found by researchers at the University of Zurich that some influenza viruses, both human and avian, can also enter cells through a second entry point that involves an immune system protein complex.

18 Jul 2024

Electron News and Research

Breakthrough Discovery on How TGF-Beta Communicates in Cells

Innovative Approach Supercharges T Cells by Transferring Healthy Mitochondria

Insights into Peptide Clumping Could Transform Drug Design and Material Science

New Insights into Python Cardiac Biology Could Inform Human Heart Disease Research

Bacterial Protein Utilizes DNA for Target Recognition and Plasmid Elimination

High-Speed Atomic Force Microscopy Reveals Cofilin Binding Patterns in Actin Filaments

Cryo-EM Study Sheds Light on HSV Drug Resistance Mechanisms Through Protein Movement

High-Resolution Structures Illuminate the Chloroplast Protein Import Machinery in Plants

Cryo-EM Reveals CDCA7's Hemimethylation Sensing in Nucleosome Core Particles

Understanding the Molecular Basis of Avian Influenza Host Shift

Mast Cells Recruit Neutrophils in Immune Response

Shared Mechanisms in Human and Yeast DNA Replication Revealed

Innovative Nanosensing Method Promises Safer Gene Therapy with Improved AAV Vector Quality

Novel Microscopy Method Revolutionizes Imaging with Reduced Radiation and Faster Results

Breakthrough in Understanding Brain's Master Protein

Cryo-EM Reveals Structural Differences in Fetal and Adult Muscle Receptors

Harvard Researchers Crack the Code on Western Equine Encephalitis Decline

Probing Plasma Membrane Dynamics with Cryo-Electron Microscopy

High Performance SEM Helps Drive NZ Towards a Smart, Green Future

Flu Virus Exploits Immune System Weakness to Infect Cells

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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