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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

New Strategy Reinvigorates Exhausted T Cells to Fight Cancer

As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T cells -; which have lost their cancer-fighting oomph -; consume this lactic acid, which further saps their energy, according to new research from the University of Pittsburgh and UPMC Hillman Cancer Center.

11 Nov 2024

Researchers Provide Genetic Diagnosis for 30 Long-Term Undiagnosed Cases

An international team of researchers has provided a genetic diagnosis for 30 individuals whose condition was undiagnosed for years despite extensive clinical or genetic testing.

11 Nov 2024

New Insights into the Molecular Basis of Mitochondrial Diseases

A significant finding about the energy production process of human cells has been made by researchers at the Karolinska Institute's Department of Cell and Molecular Biology.

11 Nov 2024

Drug Adsorption on Nano-Plastics: Could Plastic Particles Reduce Antibiotic Efficacy?

Interactions between tetracycline and nano-plastics alter drug stability and bioavailability, raising concerns about antibiotic resistance in ecosystems.

11 Nov 2024

Using Machine Learning to Understand Gene Interactions

By examining changes in gene expression, researchers gain insights into how cells operate at a molecular level, which can contribute to a better understanding of the onset of various diseases.

8 Nov 2024

CRISPR Reveals Hidden Functions of Noncoding RNA

Genes contain instructions for protein production, with the central dogma of biology stating that this information flows from DNA to RNA to proteins.

8 Nov 2024

UAB Develops a Polygenic Score to Predict Cancer Drug Resistance

In 1937, President Franklin Roosevelt signed the National Cancer Act, launching a nationwide effort to combat the disease.

8 Nov 2024

Astrocytes Play Key Role in Memory Storage and Recall, Study Shows

A study published in Nature by researchers at Baylor College of Medicine changes the way we understand memory.

7 Nov 2024

MIT Engineers Develop Model to Decode Complex Biological Systems

Over the past two decades, new technologies have helped scientists generate a vast amount of biological data. Large-scale experiments in genomics, transcriptomics, proteomics, and cytometry can produce enormous quantities of data from a given cellular or multicellular system.

6 Nov 2024

Study Reveals How Chronic Immune Signaling Can Promote Cancer

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways -; ways that have important implications for the development of cancer, researchers at Memorial Sloan Kettering Cancer Center (MSK) are discovering.

6 Nov 2024

16 Types of Nerve Cells Found to be Involved in Human Sense of Touch

No less than 16 different types of nerve cells have been identified by scientists in a new study on the human sense of touch.

6 Nov 2024

AI and Bioinformatics Reveal Genes Linked to Rheumatoid Arthritis and Osteoporosis

Rheumatoid arthritis is a common disease affecting an estimated 17 million people worldwide. The disease is caused by immune cells attacking the joints and can result in pain, swelling, and damage to the cartilage and bone.

6 Nov 2024

Novel Mechanism of Resistance to Bt Crops in a Major Agricultural Pest

Insect pests can destroy crops if they are not controlled. Crops that produce bacterial proteins that kill important pests without endangering humans or wildlife have been genetically modified to limit damage and lessen the need for insecticide sprays.

5 Nov 2024

Researchers Develop Synthetic Genes for Self-Assembling Biomaterials

Researchers from the UCLA Samueli School of Engineering and the University of Rome Tor Vergata in Italy have developed synthetic genes that function like the genes in living cells.

5 Nov 2024

APOE4 and Microglia Together Drive Alzheimer's Protein Deposits

In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein-;the most important genetic risk factor for Alzheimer's disease-;the same cells cause harmful inflammation and clumps of misfolded proteins, according to a new study by scientists at Gladstone Institutes.

5 Nov 2024

A Genomic Blueprint for Sustainable Macadamia Production

The genomes of all four Macadamia species have been successfully sequenced and combined by a research team, which represents a major breakthrough in crop development efforts for this commercially valuable nut.

4 Nov 2024

3D Tumor Microenvironment Model Highlights Role of Ischemia and Acidification in Cancer Spread

Developed 3MIC model simulates tumor microenvironments, enabling direct observation of ischemic effects on cancer cell invasiveness and drug resistance.

4 Nov 2024

New Genome Assembly Supports Climate-Smart Breeding

An international research collaboration has completed the most detailed genome assembly to date of grass pea (Lathyrus sativus).

4 Nov 2024

ALDH3A2 Enzyme Controls Red-Yellow Pigment Balance in Parrots

A single enzyme fine-tunes red and yellow pigments in parrots' polychromatic plumage, according to a new study. The findings reveal new insights into the molecular mechanisms underlying the evolution and display of color variation in one of nature's most colorful birds. Colors play a central role in ecological adaptation and communication in the natural world.

4 Nov 2024

Genetically Enhanced Black Soldier Fly Larvae Provide Superior Protein Source for Livestock Feed

With the rapid increase in the global population, a "protein crisis" is expected in the near future, where the supply of protein will not be able to meet the rising demand. Fishmeal is the most common protein source that supports the production of livestock and aquaculture products, which are key protein sources for human consumption.

4 Nov 2024