Gene Editing News and Research

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Structural Insights into a Novel Gene-Editing Tool

Yutaro Shuto, Ryoya Nakagawa, and Osamu Nureki of the University of Tokyo conducted collaborative research to ascertain the spatial organization of different processes within a unique gene-editing instrument known as “prime editor.”

30 May 2024

CRISPR Screening Reveals Peptide in Human RNA Regulating Inflammation

UC Santa Cruz researchers have discovered a peptide in human RNA that regulates inflammation and may provide a new path for treating diseases such as arthritis and lupus.

27 May 2024

Multiplexed Orthogonal Base Editors for Precise Mutation Modeling

The human genome consists of around 3 billion base pairs and humans are all 99.6% identical in their genetic makeup.

23 May 2024

Colossal Biosciences and University of Melbourne Partner to Save Northern Quolls from Invasive Cane Toads

Today scientists from Colossal Biosciences, the world’s first de-extinction company, and the University of Melbourne announce a major step forward in the effort to save Australia’s endangered northern quoll (Dasyurus hallucatus) from the invasive cane toad.

11 May 2024

Small RNA-Binding Protein Promotes Prime Editing Efficiency

Through years of engineering gene-editing systems, researchers have developed a suite of tools that enable the modification of genomes in living cells, akin to 'genome surgery'.

23 Apr 2024

Enhancing Drug Discovery Through Automated Protein Labeling

Exact protein observation in cells is crucial for many scientific fields, but it has proven to be a difficult technical task, particularly in living cells where each protein needs to have its fluorescent label applied separately.

22 Apr 2024

Multi-Tailed Strucrure Expands the Horizons of mRNA Therapeutics

Messenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines

25 Mar 2024

Telomerase's Double-Edged Sword: Preventing DNA Repair Mishaps

The natural ends of chromosomes appear alarmingly like broken DNA, much as a snapped spaghetti strand is difficult to distinguish from its intact counterparts.

16 Feb 2024

Immune System Surprise: "Junk Cells" Show Ability to Fight Malaria

Researchers from The Australian National University (ANU) have discovered a previously unknown ability of a group of immune system cells, known as Atypical B cells (ABCs), to fight infectious diseases such as malaria.

9 Feb 2024

New Method Labels Viruses for Efficient Tracking and Tailoring

At the grocery store, barcodes make it quick and simple to identify products and frequently contain important details like quantity, location, and tracking.

22 Jan 2024

Gladstone Scientists Create Intricate Map of Human T Cell Function With Base Editing

In a study of historic scale, scientists at Gladstone Institutes have created an intricate map of how the immune system functions, examining the detailed molecular structures governing human T cells using the next-generation CRISPR tool known as base editing.

14 Dec 2023

CRISPR-Cas9 Enzyme's Magnesium Role Unraveled in DNA Cutting

The gene-editing technology known as CRISPR has led to revolutionary changes in agriculture, health research and more.

6 Nov 2023

Prime Editing and Base Editing Could Revolutionize Treatment for Phenylketonuria

Phenylketonuria (PKU) is a rare newborn genetic disease that impacts between 1 in 10,000 to 1 in 20,000 people, depending on the individuals' genetic ancestry. PKU causes an amino acid-;called phenylalanine (Phe)-;to build up in the bloodstream.

3 Nov 2023

Study Discovers Fanzors in Eukaryotic Organisms

Snails, algae, and amoebas all have programmable DNA-cutting enzymes called Fanzors, and a recent study from Massachusetts Institute of Technology’s (MIT) McGovern Institute for Brain Research has found hundreds of them.

16 Oct 2023

Gene-Edited Chickens in Fight Against Bird Flu

Scientists have used gene editing techniques to identify and change parts of chicken DNA that could limit the spread of the bird flu virus in the animals.

11 Oct 2023

Broken String Biosciences Strengthens Senior Leadership Team to Accelerate Product Development and Commercialization

Broken String Biosciences today announced the expansion of its senior leadership team with the appointments of Vincent Smith, PhD, as Chief Technology Officer and Jessica Rich as VP Business Development.

3 Oct 2023

PS Gene Editing Rebuilds Lost Neural Connections in Brain Disorder

A new study from the University of Minnesota is the first to show that gene therapy can mend neural connections in people with Hurler syndrome, a rare hereditary brain condition.

22 Aug 2023

Single Injection of CRISPR Gene-Editing Treatment Safely Removes SIV From Non-Human Primates

A single injection of a novel CRISPR gene-editing treatment safely and efficiently removes SIV – a virus related to the AIDS-causing agent HIV – from the genomes of non-human primates, scientists at the Lewis Katz School of Medicine at Temple University now report.

17 Aug 2023

New Gene Editing Technique Reduces Chalkiness in Rice

As global temperatures continue to rise, maintaining the quality and yield of crops adapted to lower temperatures will increasingly become a challenge.

31 Jul 2023

Using CRISPR to Improve Forest Resilience and Productivity

Researchers at North Carolina State University used a CRISPR gene-editing system to breed poplar trees with reduced levels of lignin, the major barrier to sustainable production of wood fibers, while improving their wood properties.

14 Jul 2023