Gene Silencing News and Research

RSS

Researchers take a deep dive in understanding “dark proteome”

Researchers predicted that there would be approximately 20,000 protein-coding genes when the human genome sequence was revealed two decades ago.

31 Jan 2022

Research establishes a new understanding of how DNA methylation begins in plants

Crop improvement often involves the transfer of genetic material from one organism to another to produce a valuable trait. Some major examples of crops with these so-called "transgenes" include disease-resistant cotton and beta-carotene-enhanced golden rice.

10 Nov 2021

Study reveals mechanisms promoting overall glioma tumor growth

Researchers from Northwestern Medicine unearthed the epigenetic processes involved in the regulation of multiple oncogenes in glioma cells.

31 Aug 2021

Researchers uncover cellular mechanisms by which the silencing therapies act in cells

Gene silencing therapies are used to interfere with, or "silence", the expression of genes that are associated with disorders. Now, a team at TMDU has uncovered some of the cellular mechanisms by which the silencing therapies act in cells.

7 Jul 2021

Study could help develop peptide siRNA carrier for human oral cancer

MUSC Hollings Cancer Center researchers are exploring the use of peptide carriers for the delivery of small RNA drugs as a novel treatment for cancer. The team's recent work, published online March 19 in the Molecular Therapy - Nucleic Acids journal, lays the foundation for developing a clinically relevant peptide carrier RNAi-based drug treatment strategy for human oral cancer.

25 May 2021

Study finds how SARS-CoV-2 hijacks human cell machinery to disrupt the immune response

SARS-CoV-2 hijacks human cell machinery to disrupt the immune response, enabling it to cause infection, replicate, and cause disease.

4 May 2021

New way to create eco-friendly fungicides that protect food crops

A new study has revealed an important phase in researchers’ quest to produce targeted and more eco-friendly fungicides that protect food crops.

5 Mar 2021

Scientists resolve long-standing debate over key mechanism involved in gene silencing

Scientists from Massachusetts General Hospital (MGH) have resolved a long-standing debate over how crucial gene-silencing protein detects its targets.

5 Jan 2021

Researchers identify evolutionarily conserved pathway responsible for "closing down" gene activity

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a new and evolutionarily conserved pathway responsible for "closing down" gene activity in the mammalian cell.

3 Nov 2020

Lessons from early embryo could increase the efficiency of cell reprogramming

Cell reprogramming provides an outstanding opportunity for the artificial generation of stem cells for regenerative medicine approaches in the clinic.

7 Jul 2020

Protein glycosylation plays a major role in DNA methylation

An underlying principle in molecular biology is that “DNA makes RNA makes protein.” The process of gene expression is firmly controlled in various ways.

12 Jun 2020

Scientists develop a new way to reactivate silenced genes

All cells in an organism are known to have the same genetic data but not all carry out the same function. This is because all the cells do not contain the same active genes.

19 May 2020

Geneticists can induce "stress memory" in plants

By manipulating the expression of one gene, geneticists can induce a form of "stress memory" in plants giving them the potential for more productive growth.

6 May 2020

DNA may not be the 'blueprint' for life, just a scrambled list of ingredients

The common view of heredity is that all information passed down from one generation to the next is stored in an organism's DNA. But Antony Jose, associate professor of cell biology and molecular genetics at the University of Maryland, disagrees.

23 Apr 2020